To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson’s disease research.
Find a Research Tool
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GPNMB Edited iPSC Lines
Human iPS Cell
KOLF2.1J human iPSC line with CRISPR-engineered mutations in GPNMB, including heterozygous and homozygous knockout. These lines were generated within the iPSC Neurodegeneration Initiative for Parkinson’s Disease (iNDI-PD) which is supported by the Aligning Science Across Parkinson’s (ASAP) Initiative.
VPS13C Antibody
Antibody
Rabbit monoclonal antibody directed against human/mouse/rat VPS13C. Suitable for use in immunoblotting applications. This antibody development project is part of the Aligning Science Across Parkinson’s (ASAP) Initiative.
INPP5F Antibody
Antibody
Rabbit monoclonal antibody directed against human/mouse/rat INPP5F. Suitable for use in immunoblotting applications.
ATP10B Antibody
Antibody
Rabbit monoclonal antibody directed against human ATP10B for immunoblotting applications. This antibody development project is part of the Aligning Science Across Parkinson’s (ASAP) Initiative.
Ubiquitin pS65 Phosphospecific Antibody (WB/ICC/ELISA)
Antibody
Chicken anti-pS65 Ubiquitin antibody that has undergone Fc species switching to develop a chicken reagent from the original rabbit antibody (30H3K1). The new chimeric antibody is approved for immunoblotting, immunostaining, and immunoassay use.
ATP13A2 Antibody (Hu - WB)
Antibody
Rabbit monoclonal antibody directed against human ATP13A2 for immunoblotting applications. The epitope of this antibody was mapped to AA581-586. This antibody development project is part of the Aligning Science Across Parkinson’s (ASAP) Initiative.
ATP13A2 Antibody (Hu - WB, ICC, IP)
Antibody
Rabbit monoclonal antibody directed against human ATP13A2 for immunoblotting, immunostaining, and immunoprecipitation applications. This antibody development project is part of the Aligning Science Across Parkinson’s (ASAP) Initiative.
ATP13A2 Antibody (Ms - WB, IHC, ICC, IP)
Antibody
Rabbit monoclonal antibody directed against mouse ATP13A2 for for immunoblotting, immunostaining, and immunoprecipitation applications. The epitope of this antibody was mapped to AA1029-1036. This antibody development project is part of the Aligning Science Across Parkinson’s (ASAP) Initiative.
TMEM192 Antibody (Hu)
Antibody
Rabbit monoclonal antibody directed against human TMEM192 for immunoprecipitation of lysosomes. A version of this antibody conjugated to magnetic beads is also available. This antibody was generated by Dr. Dario Alessi at the University of Dundee and deposited through the MJFF Sponsored Tools Program as part of the Aligning Science Across Parkinson’s (ASAP) Initiative.
DJ1 Exon 1-5 Deletion
Immortalized Cell
Modified WIBR3 Human ES cell line with DJ-1 Exon 1-5 deletion. This line was generated as part of the iSCORE-PD (Isogenic Stem Cell Collection to Research Parkinson’s Disease) collection created through a collaboration between the Soldner Lab, Albert Einstein College of Medicine, Hockemeyer Lab, University of California, Berkeley, Bateup Lab, University of California, Berkeley, and Rio Lab, University of California, Berkeley, and developed under the Aligning Science Across Parkinson’s (ASAP) initiative.
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"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic