4601 - 4625 of 5832 Results
Title
Year
- Loss of FBXO7 (PARK15) results in reduced proteasome activity and models a parkinsonism‐like phenotype in mice2016OPENTitle: Loss of FBXO7 (PARK15) results in reduced proteasome activity and models a parkinsonism‐like phenotype in miceJournal Name: The EMBO JournalPublisher: Springer Science and Business Media LLCVol: 35Issue #: 18Start Page: 2008End Page: 2025Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.15252/embj.201593585Best OA location URL: https://europepmc.org/articles/pmc5282834?pdf=renderCitation Count: 63
- Predictive Big Data Analytics: A Study of Parkinson’s Disease Using Large, Complex, Heterogeneous, Incongruent, Multi-Source and Incomplete Observations2016OPENTitle: Predictive Big Data Analytics: A Study of Parkinson’s Disease Using Large, Complex, Heterogeneous, Incongruent, Multi-Source and Incomplete ObservationsJournal Name: PLOS ONEPublisher: Public Library of Science (PLoS)Vol: 11Issue #: 8Start Page: e0157077End Page: e0157077Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0157077Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0157077&type=printableCitation Count: 122
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OPENTitle: Commentary: XBP-1 Is a Cell-Nonautonomous Regulator of Stress Resistance and LongevityJournal Name: Frontiers in Aging NeurosciencePublisher: Frontiers Media SAVol: 8Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnagi.2016.00182Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnagi.2016.00182/pdfCitation Count: 5
- Caspase-1 causes truncation and aggregation of the Parkinson’s disease-associated protein α-synuclein2016OPENTitle: Caspase-1 causes truncation and aggregation of the Parkinson’s disease-associated protein α-synucleinJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 113Issue #: 34Start Page: 9587End Page: 9592Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1610099113Best OA location URL: https://www.pnas.org/content/pnas/113/34/9587.full.pdfCitation Count: 231
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OPENTitle: LRRK2 variation and dementia with Lewy bodiesJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 31Issue #:Start Page: 98End Page: 103Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2016.07.015Best OA location URL: https://europepmc.org/articles/pmc5048558?pdf=renderCitation Count: 36
- Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors2016OPENTitle: Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitorsJournal Name: Biochemical JournalPublisher: Portland Press Ltd.Vol: 473Issue #: 17Start Page: 2671End Page: 2685Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1042/bcj20160557Best OA location URL: https://portlandpress.com/biochemj/article-pdf/473/17/2671/687564/bj4732671.pdfCitation Count: 156
- Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein‐specific antibodies2016OPENTitle: Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein‐specific antibodiesJournal Name: Aging CellPublisher: WileyVol: 15Issue #: 5Start Page: 953End Page: 963Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1111/acel.12508Best OA location URL: https://www.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/acel.12508Citation Count: 23
- Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson’s disease patients2016OPENTitle: Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson’s disease patientsJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep30793Best OA location URL: https://www.nature.com/articles/srep30793.pdfCitation Count: 32
- miR-27a and miR-27b regulate autophagic clearance of damaged mitochondria by targeting PTEN-induced putative kinase 1 (PINK1)2016OPENTitle: miR-27a and miR-27b regulate autophagic clearance of damaged mitochondria by targeting PTEN-induced putative kinase 1 (PINK1)Journal Name: Molecular NeurodegenerationPublisher: Springer Science and Business Media LLCVol: 11Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13024-016-0121-4Best OA location URL: https://molecularneurodegeneration.biomedcentral.com/track/pdf/10.1186/s13024-016-0121-4Citation Count: 118
- Development and Antiparkinsonian Activity of VU0418506, a Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor 4 Homomers without Activity at mGlu2/4 Heteromers2016OPENTitle: Development and Antiparkinsonian Activity of VU0418506, a Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor 4 Homomers without Activity at mGlu2/4 HeteromersJournal Name: ACS Chemical NeurosciencePublisher: American Chemical Society (ACS)Vol: 7Issue #: 9Start Page: 1201End Page: 1211Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/acschemneuro.6b00036Best OA location URL: https://europepmc.org/articles/pmc5073817?pdf=renderCitation Count: 55
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OPENTitle: Arm swing as a potential new prodromal marker of Parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 31Issue #: 10Start Page: 1527End Page: 1534Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26720Best OA location URL: https://europepmc.org/articles/pmc5053872?pdf=renderCitation Count: 157
- Loss of SYNJ1 dual phosphatase activity leads to early onset refractory seizures and progressive neurological decline2016OPENTitle: Loss of SYNJ1 dual phosphatase activity leads to early onset refractory seizures and progressive neurological declineJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 139Issue #: 9Start Page: 2420End Page: 2430Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/brain/aww180Best OA location URL: https://academic.oup.com/brain/article-pdf/139/9/2420/17944760/aww180.pdfCitation Count: 74
- Manual-Protocol Inspired Technique for Improving Automated MR Image Segmentation during Label Fusion2016OPENTitle: Manual-Protocol Inspired Technique for Improving Automated MR Image Segmentation during Label FusionJournal Name: Frontiers in NeurosciencePublisher: Frontiers Media SAVol: 10Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnins.2016.00325Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnins.2016.00325/pdfCitation Count: 11
- LRRK2 and RAB7L1 coordinately regulate axonal morphology and lysosome integrity in diverse cellular contexts2016OPENTitle: LRRK2 and RAB7L1 coordinately regulate axonal morphology and lysosome integrity in diverse cellular contextsJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep29945Best OA location URL: https://doi.org/10.1038/srep29945Citation Count: 125
- Atrophy and structural covariance of the cholinergic basal forebrain in primary progressive aphasia2016OPENTitle: Atrophy and structural covariance of the cholinergic basal forebrain in primary progressive aphasiaJournal Name: CortexPublisher: Elsevier BVVol: 83Issue #:Start Page: 124End Page: 135Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.cortex.2016.07.004Best OA location URL: https://doi.org/10.1016/j.cortex.2016.07.004Citation Count: 20
- Comparison of the ligand binding site of CYP2C8 with CYP26A1 and CYP26B1: a structural basis for the identification of new inhibitors of the retinoic acid hydroxylases2016OPENTitle: Comparison of the ligand binding site of CYP2C8 with CYP26A1 and CYP26B1: a structural basis for the identification of new inhibitors of the retinoic acid hydroxylasesJournal Name: Journal of Enzyme Inhibition and Medicinal ChemistryPublisher: Informa UK LimitedVol: 31Issue #: sup2Start Page: 148End Page: 161Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1080/14756366.2016.1193734Best OA location URL: https://www.tandfonline.com/doi/pdf/10.1080/14756366.2016.1193734?needAccess=trueCitation Count: 12
- Levels of tau protein in plasma are associated with neurodegeneration and cognitive function in a population‐based elderly cohort2016OPENTitle: Levels of tau protein in plasma are associated with neurodegeneration and cognitive function in a population‐based elderly cohortJournal Name: Alzheimer's & DementiaPublisher: WileyVol: 12Issue #: 12Start Page: 1226End Page: 1234Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.jalz.2016.06.001Best OA location URL: https://europepmc.org/articles/pmc5148697?pdf=renderCitation Count: 114
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OPENTitle: Nilotinib – Differentiating the Hope from the HypeJournal Name: Journal of Parkinson’s DiseasePublisher: SAGE PublicationsVol: 6Issue #: 3Start Page: 519End Page: 522Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.3233/jpd-160904Best OA location URL: https://content.iospress.com:443/download/journal-of-parkinsons-disease/jpd160904?id=journal-of-parkinsons-disease%2Fjpd160904Citation Count: 29
- Subcortical Volumes Differ in Parkinson’s Disease Motor Subtypes: New Insights into the Pathophysiology of Disparate Symptoms2016OPENTitle: Subcortical Volumes Differ in Parkinson’s Disease Motor Subtypes: New Insights into the Pathophysiology of Disparate SymptomsJournal Name: Frontiers in Human NeurosciencePublisher: Frontiers Media SAVol: 10Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnhum.2016.00356Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnhum.2016.00356/pdfCitation Count: 52
- Using Qualitative Methods to Understand Physical Activity and Weight Management Among Bangladeshis in New York City, 20132016OPENTitle: Using Qualitative Methods to Understand Physical Activity and Weight Management Among Bangladeshis in New York City, 2013Journal Name: Preventing Chronic DiseasePublisher: Centers for Disease Control and Prevention (CDC)Vol: 13Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: public-domainDOI - Digital Object Identifier: 10.5888/pcd13.160077Best OA location URL: https://www.cdc.gov/pcd/issues/2016/pdf/16_0077.pdfCitation Count: 19
- Semisynthetic and in Vitro Phosphorylation of Alpha-Synuclein at Y39 Promotes Functional Partly Helical Membrane-Bound States Resembling Those Induced by PD Mutations2016OPENTitle: Semisynthetic and in Vitro Phosphorylation of Alpha-Synuclein at Y39 Promotes Functional Partly Helical Membrane-Bound States Resembling Those Induced by PD MutationsJournal Name: ACS Chemical BiologyPublisher: American Chemical Society (ACS)Vol: 11Issue #: 9Start Page: 2428End Page: 2437Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/acschembio.6b00539Best OA location URL: https://europepmc.org/articles/pmc5240779?pdf=renderCitation Count: 69
- Structural model of the dimeric Parkinson’s protein LRRK2 reveals a compact architecture involving distant interdomain contacts2016OPENTitle: Structural model of the dimeric Parkinson’s protein LRRK2 reveals a compact architecture involving distant interdomain contactsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 113Issue #: 30Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1523708113Best OA location URL: https://www.pnas.org/content/pnas/113/30/E4357.full.pdfCitation Count: 146
- Hepatitis B Virus-Induced Parkin-Dependent Recruitment of Linear Ubiquitin Assembly Complex (LUBAC) to Mitochondria and Attenuation of Innate Immunity2016OPENTitle: Hepatitis B Virus-Induced Parkin-Dependent Recruitment of Linear Ubiquitin Assembly Complex (LUBAC) to Mitochondria and Attenuation of Innate ImmunityJournal Name: PLOS PathogensPublisher: Public Library of Science (PLoS)Vol: 12Issue #: 6Start Page: e1005693End Page: e1005693Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.ppat.1005693Best OA location URL: https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1005693&type=printableCitation Count: 74
- Which patients with epilepsy are at risk for psychogenic nonepileptic seizures (PNES)? A multicenter case–control study2016OPENTitle: Which patients with epilepsy are at risk for psychogenic nonepileptic seizures (PNES)? A multicenter case–control studyJournal Name: Epilepsy & BehaviorPublisher: Elsevier BVVol: 61Issue #:Start Page: 180End Page: 184Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.yebeh.2016.05.032Best OA location URL: http://hdl.handle.net/20.500.11820/76be0ff3-49d1-475b-bca4-98873900529fCitation Count: 31
- Evolution of neurodegeneration-imaging biomarkers from clinically normal to dementia in the Alzheimer disease spectrum2016OPENTitle: Evolution of neurodegeneration-imaging biomarkers from clinically normal to dementia in the Alzheimer disease spectrumJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 46Issue #:Start Page: 32End Page: 42Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2016.06.003Best OA location URL: https://europepmc.org/articles/pmc5018437?pdf=renderCitation Count: 22