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  • Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease
    2010
    Summary Details
    OPEN
    Title: Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease
    Author(s): Taye H. Hamza, Cyrus P. Zabetian, Albert Tenesa, Alain Laederach, Jennifer S. Montimurro, Dora Yearout, Denise M. Kay, Kimberly F. Doheny, Justin Paschall, Elizabeth Pugh, Victoria I. Kusel, Randall V. Collura, John W. Roberts, Alida Griffith, Ali Samii, William K. Scott, John G. Nutt, Stewart A. Factor, Haydeh Payami
    Journal Name: Nature Genetics
    Publisher: Springer Science and Business Media LLC
    Vol: 42
    Issue #: 9
    Start Page: 781
    End Page: 785
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/ng.642
    Best OA location URL: http://hdl.handle.net/20.500.11820/b0e35720-bc0d-43af-818b-6597947a050f
    Citation Count: 810
  • CaMKII regulates diacylglycerol lipase-α and striatal endocannabinoid signaling
    2013
    Summary Details
    OPEN
    Title: CaMKII regulates diacylglycerol lipase-α and striatal endocannabinoid signaling
    Author(s): Brian C. Shonesy, Xiaohan Wang, Kristie L. Rose, Teniel S Ramikie, Victoria S. Cavener, Tyler J. Rentz, Anthony J. Baucum, Nidhi Jalan‐Sakrikar, Ken Mackie, Danny G. Winder, Sachin Patel, Roger Colbran
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 16
    Issue #: 4
    Start Page: 456
    End Page: 463
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nn.3353
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3636998
    Citation Count: 82
  • Mind matters: placebo enhances reward learning in Parkinson's disease
    2014
    Summary Details
    OPEN
    Title: Mind matters: placebo enhances reward learning in Parkinson's disease
    Author(s): Liane Schmidt, Erin Kendall Braun, Tor D. Wager, Daphna Shohamy
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 17
    Issue #: 12
    Start Page: 1793
    End Page: 1797
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nn.3842
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4503317
    Citation Count: 82
  • A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology
    2018
    Summary Details
    OPEN
    Title: A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology
    Author(s): Hongjun Fu, Andrea Possenti, Rosie Freer, Yoshikazu Nakano, Nancy C. Hernandez Villegas, Maoping Tang, Paula Victoria Maglio Cauhy, Benjamin Lassus, Shuo Chen, Stephanie L. Fowler, Helen Y. Figueroa, Edward D. Huey, Gail V.W. Johnson, Michele Vendruscolo, Karen Duff
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 22
    Issue #: 1
    Start Page: 47
    End Page: 56
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41593-018-0298-7
    Citation Count: 273
  • Mutant LRRK2R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's disease
    2009
    Summary Details
    OPEN
    Title: Mutant LRRK2R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's disease
    Author(s): Yanping Li, Wencheng Liu, Tinmarla F. Oo, Lei Wang, Yi Ling Tang, Vernice Jackson‐Lewis, Chun Hui Zhou, Kindiya D. Geghman, Mikhail Bogdanov, Serge Przedborski, M. Flint Beal, Robert E. Burke, Chenjian Li
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 12
    Issue #: 7
    Start Page: 826
    End Page: 828
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nn.2349
    Best OA location URL: http://doi.org/10.1038/nn.2349
    Citation Count: 538
  • Integrating whole-genome sequencing with multi-omic data reveals the impact of structural variants on gene regulation in the human brain
    2022
    Summary Details
    OPEN
    Title: Integrating whole-genome sequencing with multi-omic data reveals the impact of structural variants on gene regulation in the human brain
    Author(s): Ricardo A. Vialle, Kátia de Paiva Lopes, David A. Bennett, John F. Crary, Towfique Raj
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 25
    Issue #: 4
    Start Page: 504
    End Page: 514
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41593-022-01031-7
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/9245608
    Citation Count: 70
  • Brain proteome-wide association study implicates novel proteins in depression pathogenesis
    2021
    Summary Details
    OPEN
    Title: Brain proteome-wide association study implicates novel proteins in depression pathogenesis
    Author(s): Thomas S. Wingo, Yue Liu, Ekaterina S. Gerasimov, Jake Gockley, Benjamin A. Logsdon, Duc M. Duong, Eric B. Dammer, Adriana Lori, Paul J. Kim, Kerry J. Ressler, Thomas G. Beach, Eric M. Reiman, Michael P. Epstein, Philip L. De Jager, James J. Lah, David A. Bennett, Nicholas T. Seyfried, Allan I. Levey, Aliza P. Wingo
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 24
    Issue #: 6
    Start Page: 810
    End Page: 817
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41593-021-00832-6
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8530461
    Citation Count: 170
  • A causal link between prediction errors, dopamine neurons and learning
    2013
    Summary Details
    OPEN
    Title: A causal link between prediction errors, dopamine neurons and learning
    Author(s): Elizabeth E. Steinberg, Ronald Keiflin, Josiah R. Boivin, Ilana B. Witten, Karl Deisseroth, Patricia H. Janak
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 16
    Issue #: 7
    Start Page: 966
    End Page: 973
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nn.3413
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3705924
    Citation Count: 936
  • Preparation of biogenic gas vesicle nanostructures for use as contrast agents for ultrasound and MRI
    2017
    Summary Details
    OPEN
    Title: Preparation of biogenic gas vesicle nanostructures for use as contrast agents for ultrasound and MRI
    Author(s): Anupama Lakshmanan, George J. Lu, Arash Farhadi, Suchita P. Nety, Martin Kunth, Audrey Lee‐Gosselin, David Maresca, Raymond W. Bourdeau, Melissa Yin, Judy Yan, Christopher Witte, Dina Malounda, F. Stuart Foster, Leif Schröder, Mikhail G. Shapiro
    Journal Name: Nature Protocols
    Publisher: Springer Science and Business Media LLC
    Vol: 12
    Issue #: 10
    Start Page: 2050
    End Page: 2080
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nprot.2017.081
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6185898
    Citation Count: 180
  • Mechanism and regulation of the Lys6-selective deubiquitinase USP30
    2017
    Summary Details
    OPEN
    Title: Mechanism and regulation of the Lys6-selective deubiquitinase USP30
    Author(s): Malte Gersch, Christina Gladkova, Alexander F. Schubert, Martin A. Michel, Sarah Maslen, David Komander
    Journal Name: Nature Structural & Molecular Biology
    Publisher: Springer Science and Business Media LLC
    Vol: 24
    Issue #: 11
    Start Page: 920
    End Page: 930
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nsmb.3475
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5757785
    Citation Count: 223
  • Activation mechanism of PINK1
    2021
    Summary Details
    OPEN
    Title: Activation mechanism of PINK1
    Author(s): Zhong Yan Gan, Sylvie Callegari, Simon A. Cobbold, Thomas R. Cotton, Michael J. Mlodzianoski, Alexander F. Schubert, Niall D. Geoghegan, Kelly L. Rogers, Andrew Leis, Grant Dewson, Alisa Glukhova, David Komander
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 602
    Issue #: 7896
    Start Page: 328
    End Page: 335
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41586-021-04340-2
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8828467
    Citation Count: 190
  • Brain-restricted mTOR inhibition with binary pharmacology
    2022
    Summary Details
    OPEN
    Title: Brain-restricted mTOR inhibition with binary pharmacology
    Author(s): Ziyang Zhang, Qi-Wen Fan, Xujun Luo, Kevin Lou, William A. Weiss, Kevan M. Shokat
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 609
    Issue #: 7928
    Start Page: 822
    End Page: 828
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41586-022-05213-y
    Best OA location URL: https://www.nature.com/articles/s41586-022-05213-y.pdf
    Citation Count: 81
  • Mechanism of parkin activation by PINK1
    2018
    Summary Details
    OPEN
    Title: Mechanism of parkin activation by PINK1
    Author(s): Christina Gladkova, Sarah Maslen, Mark Skehel, David Komander
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 559
    Issue #: 7714
    Start Page: 410
    End Page: 414
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41586-018-0224-x
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6071873
    Citation Count: 397
  • Structure of PINK1 in complex with its substrate ubiquitin
    2017
    Summary Details
    OPEN
    Title: Structure of PINK1 in complex with its substrate ubiquitin
    Author(s): Alexander F. Schubert, Christina Gladkova, Els Pardon, Jane L. Wagstaff, Stefan M.V. Freund, Jan Steyaert, Sarah Maslen, David Komander
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 552
    Issue #: 7683
    Start Page: 51
    End Page: 56
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nature24645
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6020998
    Citation Count: 189
  • Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
    2013
    Summary Details
    OPEN
    Title: Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
    Author(s): Shireen A. Sarraf, Malavika Raman, Virginia Guarani‐Pereira, Mathew E. Sowa, Edward L. Huttlin, Steven P. Gygi, J. Wade Harper
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 496
    Issue #: 7445
    Start Page: 372
    End Page: 376
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nature12043
    Best OA location URL: http://nrs.harvard.edu/urn-3:HUL.InstRepos:11878916
    Citation Count: 1020
  • Disruption of mitochondrial complex I induces progressive parkinsonism
    2021
    Summary Details
    OPEN
    Title: Disruption of mitochondrial complex I induces progressive parkinsonism
    Author(s): Patricia González‐Rodríguez, Enrico Zampese, Kristen A. Stout, Jaime N. Guzmán, Ema Ilijić, Ben Yang, Tatiana Tkatch, Mihaela Stavarache, David L. Wokosin, Lin Gao, Michael G. Kaplitt, José López‐Barneo, Paul T. Schumacker, D. James Surmeier
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 599
    Issue #: 7886
    Start Page: 650
    End Page: 656
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41586-021-04059-0
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/9189968
    Citation Count: 532
  • Within-host evolution of a gut pathobiont facilitates liver translocation
    2022
    Summary Details
    OPEN
    Title: Within-host evolution of a gut pathobiont facilitates liver translocation
    Author(s): Yi Yang, Mytien Nguyen, Varnica Khetrapal, Nicole Sonnert, Anjelica Martin, Haiwei Chen, Martin Kriegel, Noah W. Palm
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 607
    Issue #: 7919
    Start Page: 563
    End Page: 570
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41586-022-04949-x
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/9308686
    Citation Count: 158
  • Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression
    2009
    Summary Details
    OPEN
    Title: Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression
    Author(s): Kambiz N. Alavian, Paola Sgadó, Lavinia Albéri, Srinivasa Subramaniam, Horst H. Simon
    Journal Name: Neural Development
    Publisher: Springer Science and Business Media LLC
    Vol: 4
    Issue #: 1
    Start Page: 11
    End Page: 11
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/1749-8104-4-11
    Best OA location URL: https://neuraldevelopment.biomedcentral.com/counter/pdf/10.1186/1749-8104-4-11
    Citation Count: 41
  • Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease
    2013
    Summary Details
    OPEN
    Title: Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease
    Author(s): Margarita Giraldo, Francisco Lopera, Ashley L. Siniard, Jason J. Corneveaux, Isabelle Schrauwen, Julian Carvajal, Claudia Muñoz, Manuel Ramirez‐Restrepo, Chris Gaiteri, Amanda Myers, Richard J. Caselli, Kenneth S. Kosik, Eric M. Reiman, Matthew J. Huentelman
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 34
    Issue #: 8
    Start Page: 2077.e11
    End Page: 2077.e18
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2013.02.016
    Best OA location URL: http://doi.org/10.1016/j.neurobiolaging.2013.02.016
    Citation Count: 145
  • Mutational analysis of parkin and PINK1 in multiple system atrophy
    2010
    Summary Details
    OPEN
    Title: Mutational analysis of parkin and PINK1 in multiple system atrophy
    Author(s): Janet Brooks, Henry Houlden, Anna Melchers, Ansha J. Islam, Jinhui Ding, Abi Li, Reema Paudel, Tamás Révész, Janice L. Holton, Nick Wood, Andrew J. Lees, Andrew Singleton, Sonja W. Scholz
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 32
    Issue #: 3
    Start Page: 548.e5
    End Page: 548.e7
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2009.11.020
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3934211
    Citation Count: 21
  • Aberrant intracellular localization of H3k4me3 demonstrates an early epigenetic phenomenon in Alzheimer's disease
    2015
    Summary Details
    OPEN
    Title: Aberrant intracellular localization of H3k4me3 demonstrates an early epigenetic phenomenon in Alzheimer's disease
    Author(s): Diego Mastroeni, Elaine Delvaux, Jennifer Nolz, Yuyan Tan, Andrew Grover, Salvatore Oddo, Paul D. Coleman
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 36
    Issue #: 12
    Start Page: 3121
    End Page: 3129
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2015.08.017
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4838454
    Citation Count: 61
  • Multiple system atrophy is not caused by C9orf72 hexanucleotide repeat expansions
    2014
    Summary Details
    OPEN
    Title: Multiple system atrophy is not caused by C9orf72 hexanucleotide repeat expansions
    Author(s): Sonja W. Scholz, Elisa Majounie, Tamás Révész, Janice L. Holton, Michael S. Okun, Henry Houlden, Andrew Singleton
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 36
    Issue #: 2
    Start Page: 1223.e1
    End Page: 1223.e2
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2014.08.033
    Best OA location URL: http://doi.org/10.1016/j.neurobiolaging.2014.08.033
    Citation Count: 30
  • Isolation and characterization of antibody fragments selective for toxic oligomeric tau
    2014
    Summary Details
    OPEN
    Title: Isolation and characterization of antibody fragments selective for toxic oligomeric tau
    Author(s): Huilai Tian, Eliot J. Davidowitz, Patricia López, Ping He, Philip Schulz, James G. Moe, Michael R. Sierks
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 36
    Issue #: 3
    Start Page: 1342
    End Page: 1355
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2014.12.002
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4346425
    Citation Count: 27
  • MRI-based brain atrophy rates in ADNI phase 2: acceleration and enrichment considerations for clinical trials
    2015
    Summary Details
    OPEN
    Title: MRI-based brain atrophy rates in ADNI phase 2: acceleration and enrichment considerations for clinical trials
    Author(s): Xue Hua, Christopher R. K. Ching, Adam Mezher, Boris A. Gutman, Derrek P. Hibar, Priya Bhatt, Alex Leow, Clifford R. Jack, Matt A. Bernstein, Michael W. Weiner, Paul M. Thompson
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 37
    Issue #:
    Start Page: 26
    End Page: 37
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2015.09.018
    Best OA location URL: https://www.sciencedirect.com/science/article/am/pii/S0197458015004753
    Citation Count: 50
  • Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1
    2017
    Summary Details
    OPEN
    Title: Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1
    Author(s): Miao Sun, Huaye Zhang
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 60
    Issue #:
    Start Page: 129
    End Page: 140
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2017.08.024
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5653456
    Citation Count: 28
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