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MJFF Publications

551 - 600 of 6466 Results
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  • Summary Details
    OPEN
    Title: Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0605208103
    Citation Count: 599
  • Summary Details
    OPEN
    Title: Physiology versus pathology in Parkinson's disease
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0704254104
    Citation Count: 11
  • Summary Details
    OPEN
    Title: Slow progressive degeneration of nigral dopaminergic neurons in postnatal Engrailed mutant mice
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0602116103
    Citation Count: 139
  • Summary Details
    OPEN
    Title: Selective inhibition of NF-κB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0704908104
    Citation Count: 432
  • Summary Details
    OPEN
    Title: GATA transcription factors directly regulate the Parkinson's disease-linked gene α-synuclein
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0802437105
    Citation Count: 268
  • Summary Details
    OPEN
    Title: Hypothesis-based RNAi screening identifies neuroprotective genes in a Parkinson's disease model
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0711018105
    Citation Count: 292
  • Summary Details
    OPEN
    Title: The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasis
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0710685105
    Citation Count: 540
  • Summary Details
    OPEN
    Title: Derivation of midbrain dopamine neurons from human embryonic stem cells
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0404700101
    Citation Count: 974
  • Summary Details
    OPEN
    Title: Highly pathogenic H5N1 influenza virus can enter the central nervous system and induce neuroinflammation and neurodegeneration
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0900096106
    Citation Count: 459
  • Summary Details
    OPEN
    Title: Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0810996106
    Citation Count: 142
  • Summary Details
    OPEN
    Title: Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0704091104
    Citation Count: 343
  • Summary Details
    OPEN
    Title: Unexpected expression of α- and β-globin in mesencephalic dopaminergic neurons and glial cells
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0813216106
    Citation Count: 265
  • Summary Details
    OPEN
    Title: Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0902396106
    Citation Count: 231
  • Summary Details
    OPEN
    Title: In vivo demonstration that α-synuclein oligomers are toxic
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1100976108
    Citation Count: 1480
  • Summary Details
    OPEN
    Title: Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1203223109
    Citation Count: 98
  • Summary Details
    OPEN
    Title: Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1205102109
    Citation Count: 87
  • Summary Details
    OPEN
    Title: Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegeneration
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1217296110
    Citation Count: 121
  • Summary Details
    OPEN
    Title: Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivo
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1309991110
    Citation Count: 211
  • Summary Details
    OPEN
    Title: Impaired dopamine release and synaptic plasticity in the striatum of PINK1 -deficient mice
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0702717104
    Citation Count: 537
  • Summary Details
    OPEN
    Title: R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0906334106
    Citation Count: 309
  • Summary Details
    OPEN
    Title: Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1312701111
    Citation Count: 125
  • Summary Details
    OPEN
    Title: Abrogation of α-synuclein–mediated dopaminergic neurodegeneration in LRRK2-deficient rats
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1403215111
    Citation Count: 224
  • Summary Details
    OPEN
    Title: Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1321785111
    Citation Count: 342
  • Summary Details
    OPEN
    Title: Parkinson disease-associated mutation R1441H in LRRK2 prolongs the “active state” of its GTPase domain
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1323285111
    Citation Count: 116
  • Summary Details
    OPEN
    Title: Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1321845111
    Citation Count: 213
  • Summary Details
    OPEN
    Title: α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1417883112
    Citation Count: 150
  • Summary Details
    OPEN
    Title: CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivo
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1519430112
    Citation Count: 30
  • Summary Details
    OPEN
    Title: Stochastic electrotransport selectively enhances the transport of highly electromobile molecules
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1510133112
    Citation Count: 264
  • Summary Details
    OPEN
    Title: Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson’s disease
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1509742112
    Citation Count: 192
  • Summary Details
    OPEN
    Title: Caspase-1 causes truncation and aggregation of the Parkinson’s disease-associated protein α-synuclein
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1610099113
    Citation Count: 265
  • Summary Details
    OPEN
    Title: Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1220399110
    Citation Count: 207
  • Summary Details
    OPEN
    Title: Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neurons
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1608784113
    Citation Count: 59
  • Summary Details
    OPEN
    Title: Nrf2 mitigates LRRK2- and α-synuclein–induced neurodegeneration by modulating proteostasis
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1522872114
    Citation Count: 120
  • Summary Details
    OPEN
    Title: Alterations of p11 in brain tissue and peripheral blood leukocytes in Parkinson’s disease
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1621218114
    Citation Count: 40
  • Summary Details
    OPEN
    Title: Identification of a highly neurotoxic α-synuclein species inducing mitochondrial damage and mitophagy in Parkinson’s disease
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1713849115
    Citation Count: 227
  • Summary Details
    OPEN
    Title: Regulation of myeloid cell phagocytosis by LRRK2 via WAVE2 complex stabilization is altered in Parkinson’s disease
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1718946115
    Citation Count: 117
  • Summary Details
    OPEN
    Title: On the fallacy of quantitative segmentation for T1-weighted MRI
    Journal Name: SPIE Proceedings
    Publisher: SPIE
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1117/12.2216994
    Citation Count: 5
  • Summary Details
    OPEN
    Title: Improving cerebellar segmentation with statistical fusion
    Journal Name: SPIE Proceedings
    Publisher: SPIE
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1117/12.2216966
    Citation Count: 7
  • Summary Details
    OPEN
    Title: Maladaptive striatal plasticity in l-DOPA-induced dyskinesia
    Journal Name: Progress in Brain Research
    Publisher: Elsevier
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/s0079-6123(10)83011-0
    Citation Count: 214
  • Summary Details
    OPEN
    Title: Pharmacologically distinct pramipexole-mediated akinesia vs. risk-taking in a rat model of Parkinson's disease
    Journal Name: Progress in Neuro-Psychopharmacology and Biological Psychiatry
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.pnpbp.2016.05.004
    Citation Count: 26
  • Summary Details
    OPEN
    Title: Physico-chemical determinants of soluble intrabody expression in mammalian cell cytoplasm
    Journal Name: Protein Engineering, Design and Selection
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/protein/gzq022
    Citation Count: 63
  • Summary Details
    OPEN
    Title: mzStudio: A Dynamic Digital Canvas for User-Driven Interrogation of Mass Spectrometry Data
    Journal Name: Proteomes
    Publisher: MDPI AG
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3390/proteomes5030020
    Citation Count: 26
  • Summary Details
    OPEN
    Title: Why Do We Need Multifunctional Neuroprotective and Neurorestorative Drugs for Parkinson’s and Alzheimer’s Disorders?
    Journal Name: Rambam Maimonides Medical Journal
    Publisher: Rambam Health Corporation
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.5041/rmmj.10011
    Citation Count: 8
  • Summary Details
    OPEN
    Title: Identification of extracellular miRNA in human cerebrospinal fluid by next-generation sequencing
    Journal Name: RNA
    Publisher: Cold Spring Harbor Laboratory
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1261/rna.036863.112
    Citation Count: 189
  • Summary Details
    OPEN
    Title: CNTRICS Imaging Biomarkers Final Task Selection: Long-Term Memory and Reinforcement Learning
    Journal Name: Schizophrenia Bulletin
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/schbul/sbr168
    Citation Count: 28
  • Summary Details
    OPEN
    Title: Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseases
    Journal Name: Scientific Data
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/sdata.2016.89
    Citation Count: 529
  • Summary Details
    OPEN
    Title: Global quantitative analysis of the human brain proteome in Alzheimer’s and Parkinson’s Disease
    Journal Name: Scientific Data
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/sdata.2018.36
    Citation Count: 264
  • Summary Details
    OPEN
    Title: Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-sa
    DOI - Digital Object Identifier: 10.1038/srep00700
    Citation Count: 504
  • Summary Details
    OPEN
    Title: Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson disease
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1038/srep01393
    Citation Count: 160
  • Summary Details
    OPEN
    Title: Quantitative Measurement of Intact Alpha-Synuclein Proteoforms from Post-Mortem Control and Parkinson's Disease Brain Tissue by Intact Protein Mass Spectrometry
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-sa
    DOI - Digital Object Identifier: 10.1038/srep05797
    Citation Count: 171
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