601 - 650 of 6403 Results
Title
Year
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OPENTitle: Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neuronsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 106Issue #: 7Start Page: 2429End Page: 2434Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0810996106Best OA location URL: http://doi.org/10.1073/pnas.0810996106Citation Count: 141
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OPENTitle: Neurologist-associated reduction in PD-related hospitalizations and health care expendituresJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 79Issue #: 17Start Page: 1774End Page: 1780Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0b013e3182703f92Citation Count: 98
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OPENTitle: Do Stable Patients With a Premorbid Depression History Have a Worse Outcome After Deep Brain Stimulation for Parkinson Disease?Journal Name: NeurosurgeryPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 69Issue #: 2Start Page: 357End Page: 361Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1227/neu.0b013e3182160456Citation Count: 23
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OPENTitle: Use of a self-rating scale of the nature and severity of symptoms in Parkinson’s Disease (PRO-PD): Correlation with quality of life and existing scales of disease severityJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-017-0021-5Best OA location URL: https://www.nature.com/articles/s41531-017-0021-5.pdfCitation Count: 42
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OPENTitle: Loss of Thr286 phosphorylation disrupts synaptic CaMKIIα targeting, NMDAR activity and behavior in pre-adolescent miceJournal Name: Molecular and Cellular NeurosciencePublisher: Elsevier BVVol: 47Issue #: 4Start Page: 286End Page: 292Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.mcn.2011.05.006Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3149813Citation Count: 47
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OPENTitle: Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotypingJournal Name: Nature ProtocolsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 11Start Page: 1860End Page: 1896Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nprot.2015.122Citation Count: 258
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OPENTitle: Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S miceJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 41Issue #: 3Start Page: 706End Page: 716Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2010.12.008Citation Count: 185
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OPENTitle: Neuromelanin Activates Microglia and Induces Degeneration of Dopaminergic Neurons: Implications for Progression of Parkinson’s DiseaseJournal Name: Neurotoxicity ResearchPublisher: Springer Science and Business Media LLCVol: 19Issue #: 1Start Page: 63End Page: 72Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s12640-009-9140-zCitation Count: 234
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OPENTitle: LRRK2 levels in immune cells are increased in Parkinson’s diseaseJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-017-0010-8Best OA location URL: https://doi.org/10.1038/s41531-017-0010-8Citation Count: 237
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OPENTitle: The alpha-synuclein 5′untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and PosiphenJournal Name: Journal of Neural TransmissionPublisher: Springer Science and Business Media LLCVol: 118Issue #: 3Start Page: 493End Page: 507Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s00702-010-0513-5Citation Count: 71
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OPENTitle: Elevated 5hmC levels characterize DNA of the cerebellum in Parkinson’s diseaseJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-017-0007-3Best OA location URL: https://www.nature.com/articles/s41531-017-0007-3.pdfCitation Count: 32
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OPENTitle: Vascular endothelial growth factor is upregulated by l-dopa in the parkinsonian brain: implications for the development of dyskinesiaJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 134Issue #: 8Start Page: 2339End Page: 2357Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/brain/awr165Best OA location URL: https://academic.oup.com/brain/article-pdf/134/8/2339/13735225/awr165.pdfCitation Count: 134
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OPENTitle: Discovery of Potent, Novel Nrf2 Inducers Via Quantum Modeling, Virtual Screening, and In Vitro Experimental ValidationJournal Name: Chemical Biology & Drug DesignPublisher: WileyVol: 80Issue #: 6Start Page: 810End Page: 820Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/cbdd.12040Citation Count: 16
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OPENTitle: Radiosynthesis and in Vivo Evaluation of Two PET Radioligands for Imaging α-SynucleinJournal Name: Applied SciencesPublisher: MDPI AGVol: 4Issue #: 1Start Page: 66End Page: 78Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3390/app4010066Best OA location URL: https://www.mdpi.com/2076-3417/4/1/66/pdf?version=1395063831Citation Count: 55
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OPENTitle: Chromosomal amplification of leucine-rich repeat kinase-2 (LRRK2) is required for oncogenic MET signaling in papillary renal and thyroid carcinomasJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 108Issue #: 4Start Page: 1439End Page: 1444Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1012500108Citation Count: 88
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OPENTitle: Increasing the use of mobile technology–derived endpoints in clinical trialsJournal Name: Clinical TrialsPublisher: SAGE PublicationsVol: 15Issue #: 3Start Page: 313End Page: 315Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1177/1740774518755393Best OA location URL: https://journals.sagepub.com/doi/pdf/10.1177/1740774518755393Citation Count: 23
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OPENTitle: Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathwayJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 34Issue #: 1Start Page: 95End Page: 106Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2008.12.007Best OA location URL: http://doi.org/10.1016/j.nbd.2008.12.007Citation Count: 222
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OPENTitle: Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's diseaseJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 34Issue #: 8Start Page: 2077.e11End Page: 2077.e18Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2013.02.016Best OA location URL: http://doi.org/10.1016/j.neurobiolaging.2013.02.016Citation Count: 141
- Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases2017OPENTitle: Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseasesJournal Name: Alzheimer's & DementiaPublisher: WileyVol: 14Issue #: 3Start Page: 352End Page: 366Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.jalz.2017.09.012Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.jalz.2017.09.012Citation Count: 140
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OPENTitle: Dysrhythmia of timed movements in Parkinson׳s disease and freezing of gaitJournal Name: Brain ResearchPublisher: Elsevier BVVol: 1624Issue #:Start Page: 222End Page: 231Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.brainres.2015.07.041Best OA location URL: http://doi.org/10.1016/j.brainres.2015.07.041Citation Count: 27
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OPENTitle: The microbiome of the human lower airways: a next generation sequencing perspectiveJournal Name: World Allergy Organization JournalPublisher: Elsevier BVVol: 8Issue #:Start Page: 23End Page: 23Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1186/s40413-015-0074-zBest OA location URL: http://www.worldallergyorganizationjournal.org/article/S1939455119302200/pdfCitation Count: 43
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OPENTitle: Analysis of Mitochondrial haemoglobin in Parkinson's disease brainJournal Name: MitochondrionPublisher: Elsevier BVVol: 29Issue #:Start Page: 45End Page: 52Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1016/j.mito.2016.05.001Best OA location URL: https://doi.org/10.1016/j.mito.2016.05.001Citation Count: 26
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OPENTitle: Is the N-Back Task a Valid Neuropsychological Measure for Assessing Working Memory?Journal Name: Archives of Clinical NeuropsychologyPublisher: Oxford University Press (OUP)Vol: 24Issue #: 7Start Page: 711End Page: 717Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/arclin/acp063Best OA location URL: https://academic.oup.com/acn/article-pdf/24/7/711/11189/acp063.pdfCitation Count: 210
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OPENTitle: Light sensitization of DNA nanostructures via incorporation of photo-cleavable spacersJournal Name: Chemical CommunicationsPublisher: Royal Society of Chemistry (RSC)Vol: 51Issue #: 26Start Page: 5747End Page: 5750Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1039/c5cc00082cBest OA location URL: http://doi.org/10.1039/c5cc00082cCitation Count: 55
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OPENTitle: Aberrant intracellular localization of H3k4me3 demonstrates an early epigenetic phenomenon in Alzheimer's diseaseJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 36Issue #: 12Start Page: 3121End Page: 3129Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2015.08.017Best OA location URL: http://doi.org/10.1016/j.neurobiolaging.2015.08.017Citation Count: 54
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OPENTitle: Placebo effect of medication cost in Parkinson diseaseJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 84Issue #: 8Start Page: 794End Page: 802Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0000000000001282Best OA location URL: https://n.neurology.org/content/neurology/84/8/794.full.pdfCitation Count: 129
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OPENTitle: Quantification of brain cholinergic denervation in dementia with Lewy bodies using PET imaging with [18F]-FEOBVJournal Name: Molecular PsychiatryPublisher: Springer Science and Business Media LLCVol: 24Issue #: 3Start Page: 322End Page: 327Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/s41380-018-0130-5Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6363916Citation Count: 64
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OPENTitle: Reduced RAN Expression and Disrupted Transport between Cytoplasm and Nucleus; A Key Event in Alzheimer’s Disease PathophysiologyJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 8Issue #: 1Start Page: e53349End Page: e53349Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0053349Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0053349&type=printableCitation Count: 72
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OPENTitle: SMG1 Identified as a Regulator of Parkinson’s Disease-Associated alpha-Synuclein through siRNA ScreeningJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 8Issue #: 10Start Page: e77711End Page: e77711Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0077711Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0077711&type=printableCitation Count: 17
- Quantitative neuropathology associated with chronic manganese exposure in South African mine workers2014OPENTitle: Quantitative neuropathology associated with chronic manganese exposure in South African mine workersJournal Name: NeuroToxicologyPublisher: Elsevier BVVol: 45Issue #:Start Page: 260End Page: 266Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neuro.2013.12.008Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4072755Citation Count: 45
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OPENTitle: Bapineuzumab Alters Aβ Composition: Implications for the Amyloid Cascade Hypothesis and Anti-Amyloid ImmunotherapyJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 8Issue #: 3Start Page: e59735End Page: e59735Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0059735Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0059735&type=printableCitation Count: 34
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OPENTitle: Use of Florbetapir-PET for Imaging β-Amyloid PathologyJournal Name: JAMAPublisher: American Medical Association (AMA)Vol: 305Issue #: 3Start Page: 275End Page: 275Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/jama.2010.2008Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7041965Citation Count: 1029
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OPENTitle: M1-positive allosteric modulators lacking agonist activity provide the optimal profile for enhancing cognitionJournal Name: NeuropsychopharmacologyPublisher: Springer Science and Business Media LLCVol: 43Issue #: 8Start Page: 1763End Page: 1771Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/s41386-018-0033-9Best OA location URL: https://www.nature.com/articles/s41386-018-0033-9.pdfCitation Count: 73
- Clinician versus machine: Reliability and responsiveness of motor endpoints in Parkinson's disease2014OPENTitle: Clinician versus machine: Reliability and responsiveness of motor endpoints in Parkinson's diseaseJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 20Issue #: 6Start Page: 590End Page: 595Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2014.02.022Citation Count: 147
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OPENTitle: Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4). Part II: Challenges in hit-to-leadJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 19Issue #: 3Start Page: 962End Page: 966Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2008.11.104Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3787871Citation Count: 55
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OPENTitle: Parkinson’s disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structuresJournal Name: Journal of Neural TransmissionPublisher: Springer Science and Business Media LLCVol: 118Issue #: 5Start Page: 795End Page: 808Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s00702-011-0653-2Citation Count: 265
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OPENTitle: Discovery, Characterization, and Antiparkinsonian Effect of Novel Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4Journal Name: Molecular PharmacologyPublisher: Elsevier BVVol: 74Issue #: 5Start Page: 1345End Page: 1358Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1124/mol.108.049551Best OA location URL: http://doi.org/10.1124/mol.108.049551Citation Count: 185
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OPENTitle: Extra‐nigral pathological conditions are common in Parkinson's disease with freezing of gait: An in vivo positron emission tomography studyJournal Name: Movement DisordersPublisher: WileyVol: 29Issue #: 9Start Page: 1118End Page: 1124Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.25929Best OA location URL: https://hdl.handle.net/2027.42/108363Citation Count: 112
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OPENTitle: Screening for Novel LRRK2 Inhibitors Using a High-Throughput TR-FRET Cellular Assay for LRRK2 Ser935 PhosphorylationJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 7Issue #: 8Start Page: e43580End Page: e43580Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0043580Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0043580&type=printableCitation Count: 38
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OPENTitle: 4-amino-7-chloroquinoline derivatives for treating Parkinson’s disease: implications for drug discoveryJournal Name: Expert Opinion on Drug DiscoveryPublisher: Informa UK LimitedVol: 11Issue #: 4Start Page: 337End Page: 341Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1517/17460441.2016.1154529Best OA location URL: https://www.tandfonline.com/doi/pdf/10.1517/17460441.2016.1154529?needAccess=trueCitation Count: 18
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OPENTitle: Sensitivity to change and prediction of global change for the Alzheimer’s QuestionnaireJournal Name: Alzheimer's Research & TherapyPublisher: Springer Science and Business Media LLCVol: 7Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13195-014-0092-zBest OA location URL: https://alzres.biomedcentral.com/track/pdf/10.1186/s13195-014-0092-zCitation Count: 129
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OPENTitle: Autonomic complaints in patients with restless legs syndromeJournal Name: Sleep MedicinePublisher: Elsevier BVVol: 14Issue #: 12Start Page: 1413End Page: 1416Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.sleep.2013.08.781Citation Count: 31
- LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP62012OPENTitle: LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6Journal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 21Issue #: 22Start Page: 4966End Page: 4979Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/hmg/dds342Best OA location URL: https://academic.oup.com/hmg/article-pdf/21/22/4966/17257652/dds342.pdfCitation Count: 101
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OPENTitle: Quinazolin-4-one Derivatives: A Novel Class of Noncompetitive NR2C/D Subunit-SelectiveN-Methyl-d-aspartate Receptor AntagonistsJournal Name: Journal of Medicinal ChemistryPublisher: American Chemical Society (ACS)Vol: 53Issue #: 15Start Page: 5476End Page: 5490Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/jm100027pCitation Count: 84
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OPENTitle: Discovery, Synthesis, and Structure–Activity Relationship Development of a Series of N-4-(2,5-Dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): Characterization of a Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 (mGlu4) with Oral Efficacy in an Antiparkinsonian Animal ModelJournal Name: Journal of Medicinal ChemistryPublisher: American Chemical Society (ACS)Vol: 54Issue #: 21Start Page: 7639End Page: 7647Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/jm200956qCitation Count: 59
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OPENTitle: Characterization of TAE684 as a potent LRRK2 kinase inhibitorJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 22Issue #: 5Start Page: 1864End Page: 1869Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2012.01.084Best OA location URL: http://hdl.handle.net/10871/35667Citation Count: 85
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OPENTitle: Administration and Scoring Variance on the ADAS-CogJournal Name: Journal of Alzheimer's DiseasePublisher: SAGE PublicationsVol: 15Issue #: 3Start Page: 461End Page: 464Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3233/jad-2008-15312Citation Count: 83
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OPENTitle: Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neuronsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 104Issue #: 4Start Page: 1325End Page: 1330Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0605208103Best OA location URL: http://doi.org/10.1073/pnas.0605208103Citation Count: 578
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OPENTitle: Balancing the basal ganglia circuitry: A possible new role for dopamine D2 receptors in health and diseaseJournal Name: Movement DisordersPublisher: WileyVol: 30Issue #: 7Start Page: 895End Page: 903Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26282Citation Count: 47
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OPENTitle: Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS)Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 20Issue #: 17Start Page: 5175End Page: 5178Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2010.07.007Citation Count: 29