4551 - 4600 of 5832 Results
Title
Year
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OPENTitle: Digitized Spiral Drawing: A Possible Biomarker for Early Parkinson’s DiseaseJournal Name: PLOS ONEPublisher: Public Library of Science (PLoS)Vol: 11Issue #: 10Start Page: e0162799End Page: e0162799Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0162799Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0162799&type=printableCitation Count: 95
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OPENTitle: mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1Journal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep35106Best OA location URL: https://doi.org/10.1038/srep35106Citation Count: 73
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OPENTitle: Additional rare variant analysis in Parkinson’s disease cases with and without known pathogenic mutations: evidence for oligogenic inheritanceJournal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol:Issue #:Start Page: ddw348End Page: ddw348Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1093/hmg/ddw348Best OA location URL: https://academic.oup.com/hmg/article-pdf/25/24/5483/10408585/ddw348.pdfCitation Count: 50
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OPENTitle: Cognitive function in 1736 participants in NINDS Exploratory Trials in PD Long-term Study-1Journal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 33Issue #:Start Page: 127End Page: 133Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2016.10.005Best OA location URL: https://europepmc.org/articles/pmc6091572?pdf=renderCitation Count: 10
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OPENTitle: Machine Learning Interface for Medical Image AnalysisJournal Name: Journal of Digital ImagingPublisher: Springer Science and Business Media LLCVol: 30Issue #: 5Start Page: 615End Page: 621Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s10278-016-9910-0Best OA location URL: https://europepmc.org/articles/pmc5603426?pdf=renderCitation Count: 58
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OPENTitle: Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseasesJournal Name: Scientific DataPublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/sdata.2016.89Best OA location URL: https://www.nature.com/articles/sdata201689.pdfCitation Count: 393
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OPENTitle: Impaired contrast sensitivity is associated with more severe cognitive impairment in Parkinson diseaseJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 34Issue #:Start Page: 15End Page: 19Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2016.10.006Best OA location URL: https://europepmc.org/articles/pmc5222688?pdf=renderCitation Count: 32
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OPENTitle: N-acetylaspartate supports the energetic demands of developmental myelination via oligodendroglial aspartoacylaseJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 96Issue #:Start Page: 323End Page: 334Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2016.10.001Best OA location URL: https://europepmc.org/articles/pmc5102763?pdf=renderCitation Count: 32
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OPENTitle: Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegansJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep34477Best OA location URL: https://www.nature.com/articles/srep34477.pdfCitation Count: 397
- Study of LRRK2 variation in tauopathy: Progressive supranuclear palsy and corticobasal degeneration2016OPENTitle: Study of LRRK2 variation in tauopathy: Progressive supranuclear palsy and corticobasal degenerationJournal Name: Movement DisordersPublisher: WileyVol: 32Issue #: 1Start Page: 115End Page: 123Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26815Best OA location URL: https://europepmc.org/articles/pmc5269612?pdf=renderCitation Count: 53
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OPENTitle: Computer keyboard interaction as an indicator of early Parkinson’s diseaseJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep34468Best OA location URL: https://doi.org/10.1038/srep34468Citation Count: 95
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OPENTitle: Perspective: Data sharing for discoveryJournal Name: NaturePublisher: Springer Science and Business Media LLCVol: 538Issue #: 7626Start Page: S4End Page: S4Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/538s4aBest OA location URL: https://www.nature.com/articles/538S4a.pdfCitation Count: 6
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OPENTitle: Cognitive impairment in Parkinson's disease: Association between patient-reported and clinically measured outcomesJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 33Issue #:Start Page: 107End Page: 114Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2016.09.025Best OA location URL: https://europepmc.org/articles/pmc5154808?pdf=renderCitation Count: 24
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OPENTitle: Integrative transcriptomic meta-analysis of Parkinson’s disease and depression identifies NAMPT as a potential blood biomarker for de novo Parkinson’s diseaseJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep34579Best OA location URL: https://www.nature.com/articles/srep34579.pdfCitation Count: 35
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OPENTitle: PREFACE: Divergent roles of ER stress in neurodegeneration and brain disordersJournal Name: Brain ResearchPublisher: Elsevier BVVol: 1648Issue #:Start Page: 527End Page: 529Publication Date:Open Access(OA) Status: OPENLicense: publisher-specific-oaDOI - Digital Object Identifier: 10.1016/j.brainres.2016.09.014Best OA location URL: http://manuscript.elsevier.com/S0006899316306229/pdf/S0006899316306229.pdfCitation Count: 1
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OPENTitle: Ade novocompound targeting α-synuclein improves deficits in models of Parkinson’s diseaseJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 139Issue #: 12Start Page: 3217End Page: 3236Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/brain/aww238Best OA location URL: https://academic.oup.com/brain/article-pdf/139/12/3217/24173157/aww238.pdfCitation Count: 131
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OPENTitle: SWATH-MS proteome profiling data comparison of DJ-1, Parkin, and PINK1 knockout rat striatal mitochondriaJournal Name: Data in BriefPublisher: Elsevier BVVol: 9Issue #:Start Page: 589End Page: 593Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1016/j.dib.2016.09.031Best OA location URL: https://doi.org/10.1016/j.dib.2016.09.031Citation Count: 12
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OPENTitle: Self-Reported Symptoms of Parkinson’s Disease by Sex and Disease DurationJournal Name: Western Journal of Nursing ResearchPublisher: SAGE PublicationsVol: 39Issue #: 11Start Page: 1412End Page: 1428Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1177/0193945916670904Best OA location URL: https://europepmc.org/articles/pmc5505809?pdf=renderCitation Count: 13
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OPENTitle: Specifically neuropathic Gaucher's mutations accelerate cognitive decline in Parkinson'sJournal Name: Annals of NeurologyPublisher: WileyVol: 80Issue #: 5Start Page: 674End Page: 685Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1002/ana.24781Best OA location URL: https://doi.org/10.1002/ana.24781Citation Count: 240
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OPENTitle: Hippocampal shape alterations are associated with regional Aβ load in cognitively normal elderly individualsJournal Name: European Journal of NeurosciencePublisher: WileyVol: 45Issue #: 10Start Page: 1241End Page: 1251Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/ejn.13408Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ejn.13408Citation Count: 9
- Characterization of a novel adeno-associated viral vector with preferential oligodendrocyte tropism2016OPENTitle: Characterization of a novel adeno-associated viral vector with preferential oligodendrocyte tropismJournal Name: Gene TherapyPublisher: Springer Science and Business Media LLCVol: 23Issue #: 11Start Page: 807End Page: 814Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/gt.2016.62Best OA location URL: https://www.nature.com/articles/gt201662.pdfCitation Count: 72
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OPENTitle: Ruminative brooding is associated with salience network coherence in early pubertal youthJournal Name: Social Cognitive and Affective NeurosciencePublisher: Oxford University Press (OUP)Vol: 12Issue #: 2Start Page: 298End Page: 310Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1093/scan/nsw133Best OA location URL: https://academic.oup.com/scan/article-pdf/12/2/298/27104291/nsw133.pdfCitation Count: 36
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OPENTitle: Functional Impairment in Miro Degradation and Mitophagy Is a Shared Feature in Familial and Sporadic Parkinson’s DiseaseJournal Name: Cell Stem CellPublisher: Elsevier BVVol: 19Issue #: 6Start Page: 709End Page: 724Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.stem.2016.08.002Best OA location URL: https://europepmc.org/articles/pmc5135570?pdf=renderCitation Count: 419
- Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies2016OPENTitle: Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodiesJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 49Issue #:Start Page: 214.e13End Page: 214.e15Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2016.08.023Best OA location URL: https://europepmc.org/articles/pmc5154872?pdf=renderCitation Count: 14
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OPENTitle: Identification of small molecules that bind to the mitochondrial protein mitoNEETJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 26Issue #: 21Start Page: 5350End Page: 5353Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2016.09.009Best OA location URL: https://europepmc.org/articles/pmc5482219?pdf=renderCitation Count: 36
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OPENTitle: Structural insights into Parkin substrate lysine targeting from minimal Miro substratesJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep33019Best OA location URL: https://www.nature.com/articles/srep33019.pdfCitation Count: 49
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OPENTitle: Dysregulation of protein phosphatase 2A in parkinson disease and dementia with lewy bodiesJournal Name: Annals of Clinical and Translational NeurologyPublisher: WileyVol: 3Issue #: 10Start Page: 769End Page: 780Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/acn3.337Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.337Citation Count: 57
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OPENTitle: No diurnal variation of classical and candidate biomarkers of Alzheimer’s disease in CSFJournal Name: Molecular NeurodegenerationPublisher: Springer Science and Business Media LLCVol: 11Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13024-016-0130-3Best OA location URL: https://molecularneurodegeneration.biomedcentral.com/track/pdf/10.1186/s13024-016-0130-3Citation Count: 20
- Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer's disease2016OPENTitle: Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer's diseaseJournal Name: The FASEB JournalPublisher: WileyVol: 30Issue #: 12Start Page: 4141End Page: 4148Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1096/fj.201600816rBest OA location URL: https://www.fasebj.org/doi/pdf/10.1096/fj.201600816RCitation Count: 336
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OPENTitle: Lack of Antiparkinsonian Effects of Systemic Injections of the Specific T-Type Calcium Channel Blocker ML218 in MPTP-Treated MonkeysJournal Name: ACS Chemical NeurosciencePublisher: American Chemical Society (ACS)Vol: 7Issue #: 11Start Page: 1543End Page: 1551Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/acschemneuro.6b00186Best OA location URL: https://europepmc.org/articles/pmc5510653?pdf=renderCitation Count: 9
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OPENTitle: Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissueJournal Name: Acta Neuropathologica CommunicationsPublisher: Springer Science and Business Media LLCVol: 4Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s40478-016-0371-yBest OA location URL: https://actaneurocomms.biomedcentral.com/track/pdf/10.1186/s40478-016-0371-yCitation Count: 65
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OPENTitle: Neuropsychiatric characteristics of GBA-associated Parkinson diseaseJournal Name: Journal of the Neurological SciencesPublisher: Elsevier BVVol: 370Issue #:Start Page: 63End Page: 69Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.jns.2016.08.059Best OA location URL: https://europepmc.org/articles/pmc5268078?pdf=renderCitation Count: 54
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OPENTitle: Associations between Performance on an Abbreviated CogState Battery, Other Measures of Cognitive Function, and Biomarkers in People at Risk for Alzheimer’s DiseaseJournal Name: Journal of Alzheimer's DiseasePublisher: SAGE PublicationsVol: 54Issue #: 4Start Page: 1395End Page: 1408Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3233/jad-160528Best OA location URL: https://europepmc.org/articles/pmc5074904?pdf=renderCitation Count: 49
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OPENTitle: Integration of transcriptomic and genomic data suggests candidate mechanisms for APOE4-mediated pathogenic action in Alzheimer’s diseaseJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep32583Best OA location URL: https://www.nature.com/articles/srep32583.pdfCitation Count: 20
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OPENTitle: Multicenter Assessment of Immunohistochemical Methods for Pathological Alpha-Synuclein in Sigmoid Colon of Autopsied Parkinson’s Disease and Control SubjectsJournal Name: Journal of Parkinson’s DiseasePublisher: SAGE PublicationsVol: 6Issue #: 4Start Page: 761End Page: 770Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3233/jpd-160888Best OA location URL: https://europepmc.org/articles/pmc5501392?pdf=renderCitation Count: 85
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OPENTitle: The polarity protein Par3 regulates APP trafficking and processing through the endocytic adaptor protein NumbJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 93Issue #:Start Page: 1End Page: 11Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2016.03.022Best OA location URL: https://europepmc.org/articles/pmc4930744?pdf=renderCitation Count: 24
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OPENTitle: Association ofGBAMutations and the E326K Polymorphism With Motor and Cognitive Progression in Parkinson DiseaseJournal Name: JAMA NeurologyPublisher: American Medical Association (AMA)Vol: 73Issue #: 10Start Page: 1217End Page: 1217Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/jamaneurol.2016.2245Best OA location URL: https://jamanetwork.com/journals/jamaneurology/articlepdf/2546252/noi160057.pdfCitation Count: 197
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OPENTitle: Loss of Pink1 modulates synaptic mitochondrial bioenergetics in the rat striatum prior to motor symptoms: concomitant complex I respiratory defects and increased complex II‐mediated respirationJournal Name: PROTEOMICS – Clinical ApplicationsPublisher: WileyVol: 10Issue #: 12Start Page: 1205End Page: 1217Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/prca.201600005Best OA location URL: https://europepmc.org/articles/pmc5810131?pdf=renderCitation Count: 29
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OPENTitle: Alpha‐synuclein RT‐QuIC in the CSF of patients with alpha‐synucleinopathiesJournal Name: Annals of Clinical and Translational NeurologyPublisher: WileyVol: 3Issue #: 10Start Page: 812End Page: 818Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/acn3.338Best OA location URL: https://doi.org/10.1002/acn3.338Citation Count: 417
- Large-Scale Wearable Sensor Deployment in Parkinson’s Patients: The Parkinson@Home Study Protocol2016OPENTitle: Large-Scale Wearable Sensor Deployment in Parkinson’s Patients: The Parkinson@Home Study ProtocolJournal Name: JMIR Research ProtocolsPublisher: JMIR Publications Inc.Vol: 5Issue #: 3Start Page: e172End Page: e172Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.2196/resprot.5990Best OA location URL: https://www.researchprotocols.org/2016/3/e172/PDFCitation Count: 64
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OPENTitle: Structural connectivity profile of scans without evidence of dopaminergic deficit (SWEDD) patients compared to normal controls and Parkinson’s disease patientsJournal Name: SpringerPlusPublisher: Springer Science and Business Media LLCVol: 5Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s40064-016-3110-8Best OA location URL: https://springerplus.springeropen.com/track/pdf/10.1186/s40064-016-3110-8Citation Count: 11
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OPENTitle: Relative vascular permeability and vascularity across different regions of the rat nasal mucosa: implications for nasal physiology and drug deliveryJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep31732Best OA location URL: https://www.nature.com/articles/srep31732.pdfCitation Count: 43
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OPENTitle: Impairment of cocaine-mediated behaviours in mice by clinically relevant Ras-ERK inhibitorsJournal Name: eLifePublisher: eLife Sciences Publications, LtdVol: 5Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.7554/elife.17111Best OA location URL: https://doi.org/10.7554/elife.17111Citation Count: 50
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OPENTitle: A novel multiplex assay for simultaneous quantification of total and S129 phosphorylated human alpha-synucleinJournal Name: Molecular NeurodegenerationPublisher: Springer Science and Business Media LLCVol: 11Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13024-016-0125-0Best OA location URL: https://molecularneurodegeneration.biomedcentral.com/track/pdf/10.1186/s13024-016-0125-0Citation Count: 38
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OPENTitle: Analysis of number needed to treat for droxidopa in patients with symptomatic neurogenic orthostatic hypotensionJournal Name: BMC NeurologyPublisher: Springer Science and Business Media LLCVol: 16Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s12883-016-0665-5Best OA location URL: https://bmcneurol.biomedcentral.com/track/pdf/10.1186/s12883-016-0665-5Citation Count: 4
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OPENTitle: LRRK2 deficiency impacts ceramide metabolism in brainJournal Name: Biochemical and Biophysical Research CommunicationsPublisher: Elsevier BVVol: 478Issue #: 3Start Page: 1141End Page: 1146Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bbrc.2016.08.082Best OA location URL: https://discovery.ucl.ac.uk/1508867/1/Plotegher.pdfCitation Count: 58
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OPENTitle: Cargo proteins of plasma astrocyte‐derived exosomes in Alzheimer's diseaseJournal Name: The FASEB JournalPublisher: WileyVol: 30Issue #: 11Start Page: 3853End Page: 3859Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1096/fj.201600756rBest OA location URL: https://www.fasebj.org/doi/pdf/10.1096/fj.201600756RCitation Count: 330
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OPENTitle: Inhibitor treatment of peripheral mononuclear cells from Parkinson’s disease patients further validates LRRK2 dephosphorylation as a pharmacodynamic biomarkerJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep31391Best OA location URL: https://www.nature.com/articles/srep31391.pdfCitation Count: 258
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OPENTitle: Parkinson's disease is ready for precision medicineJournal Name: Personalized MedicinePublisher: Informa UK LimitedVol: 13Issue #: 5Start Page: 405End Page: 407Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.2217/pme-2016-0052Best OA location URL: https://www.futuremedicine.com/doi/pdf/10.2217/pme-2016-0052Citation Count: 7
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OPENTitle: Widespread transneuronal propagation of α-synucleinopathy triggered in olfactory bulb mimics prodromal Parkinson’s diseaseJournal Name: Journal of Experimental MedicinePublisher: Rockefeller University PressVol: 213Issue #: 9Start Page: 1759End Page: 1778Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1084/jem.20160368Best OA location URL: https://rupress.org/jem/article-pdf/213/9/1759/1134774/jem_20160368.pdfCitation Count: 327