Title:Allosteric Inhibition of Parkinson’s-Linked LRRK2 by Constrained Peptides
Author(s):Leah G. Helton, Ahmed Soliman, Felix von Zweydorf, Michalis Kentros, Jascha T. Manschwetus, Scotty Hall, Bernd K. Gilsbach, Franz Y. Ho, Panagiotis S. Athanasopoulos, Ranjan K. Singh, Timothy J. LeClair, Wim Versées, Francesco Raimondi, Friedrich W. Herberg, Christian Johannes Gloeckner, Hardy J. Rideout, Arjan Kortholt, Eileen J. Kennedy
Journal Name:ACS Chemical Biology
Publisher:American Chemical Society (ACS)
Vol:16
Issue #:11
Start Page:2326
End Page:2338
Publication Date:
Open Access(OA) Status:OPEN
License:cc-by-nc-nd
DOI - Digital Object Identifier:10.1021/acschembio.1c00487
Title:Crowdsourcing digital health measures to predict Parkinson’s disease severity: the Parkinson’s Disease Digital Biomarker DREAM Challenge
Author(s):Solveig K. Sieberts, Jennifer Schaff, Marlena Duda, Bálint Pataki, Ming Sun, Phil Snyder, Jean‐François Daneault, Federico Parisi, Gianluca Costante, Udi Rubin, Peter Banda, Yooree Chae, Elias Chaibub Neto, E. Ray Dorsey, Zafer Aydın, Aipeng Chen, Laura L. Elo, Carlos Lodeiro, Enrico Glaab, Ethan Goan, Fatemeh Noushin Golabchi, Yasin Görmez, Maria K. Jaakkola, Jitendra Jonnagaddala, Riku Klén, Dongmei Li, Christian McDaniel, Dimitri Perrin, Thanneer M. Perumal, Nastaran Mohammadian Rad, Erin Rainaldi, Stefano Sapienza, Patrick Schwab, Nikolai Shokhirev, Mikko S. Venäläinen, Gloria Vergara‐Diaz, Yuqian Zhang, Avner Abrami, Aditya Adhikary, Carla Agurto, Sherry Bhalla, Halil Bilgin, Vittorio Caggiano, Jun Cheng, Eden Deng, Qiwei Gan, Rajan Girsa, Zhi Han, Stephen Heisig, Kun Huang, Samad Jahandideh, Wolfgang Kopp, Christoph Kurz, Gregor Lichtner, Raquel Norel, Gajendra P. S. Raghava, Tavpritesh Sethi, Nicholas Shawen, Vaibhav Tripathi, Matthew Tsai, Tongxin Wang, Yi Wu, Jie Zhang, Xinyu Zhang, Yuanjia Wang, Yuanfang Guan, Daniela Brunner, Paolo Bonato, Lara M. Mangravite, Larsson Omberg
Journal Name:npj Digital Medicine
Publisher:Springer Science and Business Media LLC
Vol:4
Issue #:1
Start Page:
End Page:
Publication Date:
Open Access(OA) Status:OPEN
License:cc-by, cc-by
DOI - Digital Object Identifier:10.1038/s41746-021-00414-7
Title:African ancestry neurodegeneration risk variant disrupts an intronic branchpoint in GBA1
Author(s):Pilar Álvarez Jerez, Peter Wild Crea, Daniel M. Ramos, Emil K. Gustavsson, Mandy Radefeldt, Andrey Damianov, Mary B. Makarious, Oluwadamilola O. Ojo, Kimberley J. Billingsley, Laksh Malik, Kensuke Daida, Sarah Bromberek, Fangle Hu, Zachary Schneider, Aditya Surapaneni, Julia T. Stadler, Mie Rizig, Huw R. Morris, Caroline B. Pantazis, Hampton L. Leonard, Laurel A. Screven, Yue Qi, Mike A. Nalls, Sara Bandrés‐Ciga, John Hardy, Henry Houlden, Celeste Eng, Esteban G. Burchard, Linda Kachuri, Chia-Ho Lin, Douglas L. Black, Mike A. Nalls, Andrew B. Singleton, Steffen Fischer, Peter Bauer, Xylena Reed, Mina Ryten, Christian Beetz, Michael E. Ward, Njideka Okubadejo, Cornelis Blauwendraat
Title:Remote smartphone monitoring of Parkinson’s disease and individual response to therapy
Author(s):Larsson Omberg, Elias Chaibub Neto, Thanneer M. Perumal, Abhishek Pratap, Aryton Tediarjo, Jamie Adams, Bastiaan R. Bloem, Brian M. Bot, Molly J. Elson, Samuel M. Goldman, Michael Kellen, Karl Kieburtz, Arno Klein, Max A. Little, Ruth B. Schneider, Christine Suver, Christopher G. Tarolli, Caroline M. Tanner, Andrew D. Trister, John Wilbanks, E. Ray Dorsey, Lara M. Mangravite
Journal Name:Nature Biotechnology
Publisher:Springer Science and Business Media LLC
Vol:40
Issue #:4
Start Page:480
End Page:487
Publication Date:
Open Access(OA) Status:OPEN
License:
DOI - Digital Object Identifier:10.1038/s41587-021-00974-9
Title:New insights into the genetic etiology of Alzheimer’s disease and related dementias
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Journal Name:Nature Genetics
Publisher:Springer Science and Business Media LLC
Vol:54
Issue #:4
Start Page:412
End Page:436
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Open Access(OA) Status:OPEN
License:cc-by, cc-by, cc-by
DOI - Digital Object Identifier:10.1038/s41588-022-01024-z
Title:Intra-striatal AAV2.retro administration leads to extensive retrograde transport in the rhesus macaque brain: implications for disease modeling and therapeutic development
Author(s):Alison R. Weiss, William A. Liguore, Jacqueline S. Domire, Dana Button, Jodi L. McBride
Journal Name:Scientific Reports
Publisher:Springer Science and Business Media LLC
Vol:10
Issue #:1
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Open Access(OA) Status:OPEN
License:cc-by, cc-by
DOI - Digital Object Identifier:10.1038/s41598-020-63559-7
Title:Structure of LRRK1 and mechanisms of autoinhibition and activation
Author(s):Janice M. Reimer, Andrea M. Dickey, Yu Xuan Lin, Robert G. Abrisch, Sebastian Mathea, Deep Chatterjee, Elizabeth J. Fay, Stefan Knapp, Matthew D. Daugherty, Samara L. Reck‐Peterson, Andrés E. Leschziner
Title:Triglycerides are an important fuel reserve for synapse function in the brain
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Journal Name:Nature Metabolism
Publisher:Springer Science and Business Media LLC
Vol:7
Issue #:7
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DOI - Digital Object Identifier:10.1038/s42255-025-01321-x
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