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  • RTP801 interacts with the tRNA ligase complex and dysregulates its RNA ligase activity in Alzheimer’s disease
    2024
    OPEN
    Title: RTP801 interacts with the tRNA ligase complex and dysregulates its RNA ligase activity in Alzheimer’s disease
    Author(s): Genís Campoy‐Campos, Júlia Solana‐Balaguer, Anna Guisado-Corcoll, Almudena Chicote‐González, Pol Garcia‐Segura, Leticia Pérez‐Sisqués, Adrian Gabriel Torres, Mercè Canal, Laura Molina‐Porcel, Enrique Santamaría, Enrique Santamaría, Lluı́s Ribas de Pouplana, Albert Giralt, Eulàlia Martı́, Albert Giralt, Esther Pérez‐Navarro, Cristina Malagelada
    Journal Name: Nucleic Acids Research
    Publisher: Oxford University Press (OUP)
    Vol: 52
    Issue #: 18
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1093/nar/gkae776
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    Citation Count: 0
  • Understanding what aspects of Parkinson’s disease matter most to patients and families
    2024
    OPEN
    Title: Understanding what aspects of Parkinson’s disease matter most to patients and families
    Author(s): Jennifer R. Mammen, Mirinda Brown Tyo, Joyce Cadorette, Jamie Adams, Yuge Xiao, Diane Stephenson, C. Bale
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 14
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1038/s41598-024-71555-4
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    Citation Count: 0
  • Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer
    2024
    OPEN
    Title: Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer
    Author(s): Elena Buglakova, Måns Ekelöf, Michaela Schwaiger-Haber, Lisa Schlicker, Martijn R. Molenaar, Mohammed Shahraz, Lachlan Stuart, Andreas Eisenbarth, Volker Hilsenstein, Gary J. Patti, Almut Schulze, Marteinn T. Snaebjornsson, Theodore Alexandrov
    Journal Name: Nature Metabolism
    Publisher: Springer Science and Business Media LLC
    Vol: 6
    Issue #: 9
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s42255-024-01118-4
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    Citation Count: 0
  • SVA Regulation of Transposable Element Clustered Transcription within the Major Histocompatibility Complex Genomic Class II Region of the Parkinson’s Progression Markers Initiative
    2024
    OPEN
    Title: SVA Regulation of Transposable Element Clustered Transcription within the Major Histocompatibility Complex Genomic Class II Region of the Parkinson’s Progression Markers Initiative
    Author(s): Jerzy K. Kulski, Abigail L. Pfaff, Sulev Kõks
    Journal Name: Genes
    Publisher: MDPI AG
    Vol: 15
    Issue #: 9
    Start Page: 1185
    End Page: 1185
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3390/genes15091185
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    Citation Count: 0
  • A novel super-resolution microscopy platform for cutaneous alpha-synuclein detection in Parkinson’s disease
    2024
    OPEN
    Title: A novel super-resolution microscopy platform for cutaneous alpha-synuclein detection in Parkinson’s disease
    Author(s): Ofir Sade, Daphna Fischel, Noa Barak-Broner, Shir Halevi, Irit Gottfried, Dana Bar-On, Stefan Sachs, Anat Mirelman, Avner Thaler, Aviv Gour, Meir Kestenbaum, Mali Gana Weisz, Saar Anis, Claudio Soto, Melanie Shanie Roitman, Shimon Shahar, Kathrin Doppler, Markus Sauer, Alessio Di Fonzo, Nirit Lev, Roy N. Alcalay, Sharon Hassin‐Baer, Uri Ashery
    Journal Name: Frontiers in Molecular Neuroscience
    Publisher: Frontiers Media SA
    Vol: 17
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnmol.2024.1431549
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    Citation Count: 0
  • Relationships of B12 and Homocysteine with Outcomes in the SURE-PD, SURE-PD3, and STEADY-PDIII Trials
    2024
    OPEN
    Title: Relationships of B12 and Homocysteine with Outcomes in the SURE-PD, SURE-PD3, and STEADY-PDIII Trials
    Author(s): Chadwick W. Christine, Peggy Auinger, E. Forti, Lyvin Tat, Noemi Cannizzaro, Andres Yamil Regalado Mustafa, Jay M. Iyer, David Oakes, Ralph Green
    Journal Name: Journal of Parkinson's Disease
    Publisher: SAGE Publications
    Vol: 14
    Issue #: 6
    Start Page: 1243
    End Page: 1255
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.3233/jpd-240035
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    Citation Count: 0
  • Cohort-specific Boolean models highlight different regulatory modules during Parkinson’s disease progression
    2024
    OPEN
    Title: Cohort-specific Boolean models highlight different regulatory modules during Parkinson’s disease progression
    Author(s): Ahmed Abdelmonem Hemedan, Venkata Satagopam, Reinhard Schneider, Marek Ostaszewski
    Journal Name: iScience
    Publisher: Elsevier BV
    Vol: 27
    Issue #: 10
    Start Page: 110956
    End Page: 110956
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1016/j.isci.2024.110956
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    Citation Count: 0
  • Selection of DNA aptamers that prevent the fibrillization of α-synuclein protein in cellular and mouse models
    2024
    OPEN
    Title: Selection of DNA aptamers that prevent the fibrillization of α-synuclein protein in cellular and mouse models
    Author(s): Erin M. McConnell, Dennis Chan, Katelyn Ventura, Joshua P. Callahan, Kathryn P. Harris, Vernon Hunt, Spencer Boisjoli, Daniel Knight, Emma Monk, Matthew R. Holahan, Maria C. DeRosa
    Journal Name: Molecular Therapy - Nucleic Acids
    Publisher: Elsevier BV
    Vol: 35
    Issue #: 3
    Start Page: 102251
    End Page: 102251
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.omtn.2024.102251
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    Citation Count: 1
  • SynBot is an open-source image analysis software for automated quantification of synapses
    2024
    OPEN
    Title: SynBot is an open-source image analysis software for automated quantification of synapses
    Author(s): Christabel Xin Tan, J.J. Ramirez, W. Christopher Risher, Yizhi Wang, Dolores Irala, Çağla Eroğlu
    Journal Name: Cell Reports Methods
    Publisher: Elsevier BV
    Vol: 4
    Issue #: 9
    Start Page: 100861
    End Page: 100861
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by, cc-by
    DOI - Digital Object Identifier: 10.1016/j.crmeth.2024.100861
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    Citation Count: 0
  • Validating New Symptom Emergence as a Patient-Centric Outcome Measure for PD Clinical Trials
    2024
    RESTRICTED
    Title: Validating New Symptom Emergence as a Patient-Centric Outcome Measure for PD Clinical Trials
    Author(s): Haotian Zou, Glenn T. Stebbins, Tanya Simuni, Sheng Luo, Jesse M. Cedarbaum
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 128
    Issue #:
    Start Page: 107118
    End Page: 107118
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2024.107118
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    Citation Count: 0
  • An Inducible Luminescent System to Explore Parkinson’s Disease-Associated Genes
    2024
    OPEN
    Title: An Inducible Luminescent System to Explore Parkinson’s Disease-Associated Genes
    Author(s): Axel Gandy, Gilles Maussion, S. Al-Habyan, Michaël Nicouleau, Zhipeng You, Carol X.‐Q. Chen, Narges Abdian, Nathalia Aprahamian, Andrea I. Krahn, Louise Larocque, Thomas M. Durcan, Éric Deneault
    Journal Name: International Journal of Molecular Sciences
    Publisher: MDPI AG
    Vol: 25
    Issue #: 17
    Start Page: 9493
    End Page: 9493
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3390/ijms25179493
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    Citation Count: 0
  • Bridging the gap: Multi‐omics profiling of brain tissue in Alzheimer's disease and older controls in multi‐ethnic populations
    2024
    OPEN
    Title: Bridging the gap: Multi‐omics profiling of brain tissue in Alzheimer's disease and older controls in multi‐ethnic populations
    Author(s): Joseph S. Reddy, Laura Heath, Abby Vander Linden, Mariet Allen, Kátia de Paiva Lopes, Fatemeh Seifar, Erming Wang, Yiyi Ma, William L. Poehlman, Zachary Quicksall, Alexi Runnels, Yanling Wang, Duc M. Duong, Luming Yin, Kaiming Xu, Erica Modeste, Anantharaman Shantaraman, Eric B. Dammer, Lingyan Ping, Stephanie R. Oatman, Jo Scanlan, Charlotte C.G. Ho, Minerva M. Carrasquillo, Merve Atık, Geovanna Yepez, Adriana O. Mitchell, Thuy Nguyen, Xianfeng Chen, David X. Márquez, Hasini Reddy, Harrison Xiao, Sudha Seshadri, Richard Mayeux, Stefan Prokop, Edward B. Lee, Geidy E. Serrano, Thomas G. Beach, Andrew F. Teich, V. Haroutunian, Edward J. Fox, Marla Gearing, Aliza P. Wingo, Thomas S. Wingo, James J. Lah, Allan I. Levey, Dennis W. Dickson, Lisa L. Barnes, Philip L. De Jager, Bin Zhang, David A. Bennett, Nicholas T. Seyfried, Anna K. Greenwood, Nilüfer Ertekin‐Taner
    Journal Name: Alzheimer's & Dementia
    Publisher: Wiley
    Vol:
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/alz.14208
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    Citation Count: 1
  • Inflammation and heterogeneity in synucleinopathies
    2024
    RESTRICTED
    Title: Inflammation and heterogeneity in synucleinopathies
    Author(s): Antoine Freuchet, Anaëlle Pinçon, A Sette, Cecilia S. Lindestam Arlehamn
    Journal Name: Frontiers in Immunology
    Publisher: Frontiers Media SA
    Vol: 15
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.3389/fimmu.2024.1432342
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    Citation Count: 0
  • Shared and distinct cortical morphometric alterations in five neuropsychiatric symptoms of Parkinson’s disease
    2024
    OPEN
    Title: Shared and distinct cortical morphometric alterations in five neuropsychiatric symptoms of Parkinson’s disease
    Author(s): Qianling Lu, Zhuang Zhu, Heng Zhang, Caiting Gan, Aidi Shan, Mengxi Gao, Huimin Sun, Xingyue Cao, Yongsheng Yuan, Joseph B. Tracy, Qirui Zhang, Kezhong Zhang
    Journal Name: Translational Psychiatry
    Publisher: Springer Science and Business Media LLC
    Vol: 14
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1038/s41398-024-03070-z
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    Citation Count: 0
  • Medication improves velocity, reaction time, and movement time but not amplitude or error during memory‐guided reaching in Parkinson's disease
    2024
    OPEN
    Title: Medication improves velocity, reaction time, and movement time but not amplitude or error during memory‐guided reaching in Parkinson's disease
    Author(s): Michael P. Trevarrow, Miranda J. Munoz, Yessenia M. Rivera, Rishabh Arora, Quentin H. Drane, Gian Pal, Leonard Verhagen Metman, Lisa C. Goelz, Daniel M. Corcos, Fabian J. David
    Journal Name: Physiological Reports
    Publisher: Wiley
    Vol: 12
    Issue #: 17
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.14814/phy2.16150
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    Citation Count: 0
  • Sensorimotor functioning changes in response to global exercise versus handwriting upper limb exercise training in Parkinson’s disease, results from a phase II randomised controlled trial
    2024
    OPEN
    Title: Sensorimotor functioning changes in response to global exercise versus handwriting upper limb exercise training in Parkinson’s disease, results from a phase II randomised controlled trial
    Author(s): Íbis Ariana Peña de Moraes, Johnny Collett, Talita Dias da Silva, Marloes Franssen, Surabhi Mitta, Paweł Zalewski, Andy Meaney, Derick T Wade, Hooshang Izadi, Charlotte Winward, Carlos Bandeira de Mello Monteiro, Helen Dawes
    Journal Name: PLOS ONE
    Publisher: Public Library of Science (PLoS)
    Vol: 19
    Issue #: 8
    Start Page: e0309217
    End Page: e0309217
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pone.0309217
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    Citation Count: 0
  • Single-Molecule Fingerprinting Reveals Different Growth Mechanisms in Seed Amplification Assays for Different Polymorphs of α-Synuclein Fibrils
    2024
    OPEN
    Title: Single-Molecule Fingerprinting Reveals Different Growth Mechanisms in Seed Amplification Assays for Different Polymorphs of α-Synuclein Fibrils
    Author(s): Derrick Lau, Yuan Tang, Vijaya B. Kenche, Thomas Copie, Daryan Kempe, Eve Jary, Noah J. Graves, Maté Biro, Colin L. Masters, Nicolas Dzamko, Yann Gambin, Emma Sierecki
    Journal Name: ACS Chemical Neuroscience
    Publisher: American Chemical Society (ACS)
    Vol: 15
    Issue #: 18
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1021/acschemneuro.4c00185
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    Citation Count: 0
  • Synthesis at the Interface of Chemistry and Biology
    2024
    RESTRICTED
    Title: Synthesis at the Interface of Chemistry and Biology
    Author(s): Peter G. Schultz
    Journal Name: Accounts of Chemical Research
    Publisher: American Chemical Society (ACS)
    Vol: 57
    Issue #: 18
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1021/acs.accounts.4c00320
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    Citation Count: 0
  • Diffusion tensor metrics, motor and non-motor symptoms in de novo Parkinson’s disease
    2024
    RESTRICTED
    Title: Diffusion tensor metrics, motor and non-motor symptoms in de novo Parkinson’s disease
    Author(s): Nayron Medeiros Soares, Pedro Henrique Rodrigues da Silva, Gabriela Magalhães Pereira, Renata Ferranti Leoni, Carlos Roberto de Mello Rieder, Thatiane Alves Pianoschi Alva
    Journal Name: Neuroradiology
    Publisher: Springer Science and Business Media LLC
    Vol: 66
    Issue #: 11
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1007/s00234-024-03452-6
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    Citation Count: 1
  • Acceptability of digital health technologies in early Parkinson's disease: lessons from WATCH-PD
    2024
    OPEN
    Title: Acceptability of digital health technologies in early Parkinson's disease: lessons from WATCH-PD
    Author(s): Tairmae Kangarloo, Robert D. Latzman, John Adams, Rebecca J. Dorsey, Melissa Kostrzebski, Joan Severson, David G. Anderson, Fay B. Horak, Diane Stephenson, Joshua D. Cosman
    Journal Name: Frontiers in Digital Health
    Publisher: Frontiers Media SA
    Vol: 6
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fdgth.2024.1435693
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    Citation Count: 0
  • Dynamic balance and gait impairments in Parkinson’s disease: novel cholinergic patterns
    2024
    OPEN
    Title: Dynamic balance and gait impairments in Parkinson’s disease: novel cholinergic patterns
    Author(s): Nicolaas I. Bohnen, Uroš Marušič, Stiven Roytman, Rebecca Paalanen, F. Michalakis, Theodore R. Brown, Peter J. H. Scott, Giulia Carli, Roger L. Albin, Prabesh Kanel
    Journal Name: Brain Communications
    Publisher: Oxford University Press (OUP)
    Vol: 6
    Issue #: 5
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/braincomms/fcae286
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    Citation Count: 0
  • Cell-specific expression of key mitochondrial enzymes limits OXPHOS in astrocytes of the adult human neocortex and hippocampal formation
    2024
    OPEN
    Title: Cell-specific expression of key mitochondrial enzymes limits OXPHOS in astrocytes of the adult human neocortex and hippocampal formation
    Author(s): Árpád Dobolyi, Melinda Cservenák, Attila G. Bagó, Chun Chen, Анна Степанова, Krisztina Paál, Jeonghyoun Lee, Miklós Palkovits, Gavin Hudson, Christos Chinopoulos
    Journal Name: Communications Biology
    Publisher: Springer Science and Business Media LLC
    Vol: 7
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s42003-024-06751-z
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    Citation Count: 0
  • Phosphoglycerate kinase is a central leverage point in Parkinson’s disease–driven neuronal metabolic deficits
    2024
    OPEN
    Title: Phosphoglycerate kinase is a central leverage point in Parkinson’s disease–driven neuronal metabolic deficits
    Author(s): Alexandros C. Kokotos, Aldana M. Antoniazzi, Santiago R. Unda, Myung S. Ko, Daehun Park, David Eliezer, Michael G. Kaplitt, Pietro De Camilli, Timothy A. Ryan
    Journal Name: Science Advances
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 10
    Issue #: 34
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/sciadv.adn6016
    Best OA location URL:
    Citation Count: 0
  • Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies
    2024
    OPEN
    Title: Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies
    Author(s): Paras S. Minhas, Jeffrey R. Jones, Amira Latif‐Hernandez, Yuki Sugiura, Aarooran S. Durairaj, Qian Wang, Siddhita D. Mhatre, Takeshi Uenaka, Joshua Crapser, Travis E. Conley, Hannah E. Ennerfelt, Yoo Jin Jung, Ling Liu, Praveena Prasad, Brenita C. Jenkins, Yeonglong Albert Ay, Matthew Matrongolo, Ryan Goodman, Traci Fang Newmeyer, Kelly J. Heard, Austin Kang, Edward N. Wilson, Tao Yang, Erik M. Ullian, Geidy E. Serrano, Thomas G. Beach, Marius Wernig, Joshua D. Rabinowitz, Makoto Suematsu, Frank M. Longo, Melanie R. McReynolds, Fred H. Gage, Katrin I. Andreasson
    Journal Name: Science
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 385
    Issue #: 6711
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/science.abm6131
    Best OA location URL: https://doi.org/10.1101/2024.06.23.598940
    Citation Count: 1
  • Exploring Analysis Approaches for Using the Dopamine Transporter Striatal Binding Ratio in Early‐ to Mid‐Stage Parkinson's Disease Modification Trials
    2024
    OPEN
    Title: Exploring Analysis Approaches for Using the Dopamine Transporter Striatal Binding Ratio in Early‐ to Mid‐Stage Parkinson's Disease Modification Trials
    Author(s): Nirosen Vijiaratnam, Christine Girges, Dilan Athauda, Alexa King, Grace Auld, Rachel McComish, Kashfia Chowdhury, Simon S. Skene, Kate Maclagan, К. Ray Chaudhuri, Vincenzo Libri, John Dickson, Thomas Foltynie
    Journal Name: Movement Disorders Clinical Practice
    Publisher: Wiley
    Vol: 11
    Issue #: 11
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1002/mdc3.14191
    Best OA location URL:
    Citation Count: 0
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