7051 - 7100 of 8404 Results
Title
Year
-
RESTRICTEDTitle: Bent out of shape: α‐Synuclein misfolding and the convergence of pathogenic pathways in Parkinson's diseaseJournal Name: FEBS LettersPublisher: WileyVol: 589Issue #: 24PartAStart Page: 3749End Page: 3759Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.febslet.2015.10.023Best OA location URL: https://febs.onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.febslet.2015.10.023Citation Count: 55
- Molecular heterogeneity of midbrain dopaminergic neurons – Moving toward single cell resolution2015RESTRICTEDTitle: Molecular heterogeneity of midbrain dopaminergic neurons – Moving toward single cell resolutionJournal Name: FEBS LettersPublisher: WileyVol: 589Issue #: 24PartAStart Page: 3714End Page: 3726Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.febslet.2015.10.022Best OA location URL: https://febs.onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.febslet.2015.10.022Citation Count: 69
-
OPENTitle: MRI-based brain atrophy rates in ADNI phase 2: acceleration and enrichment considerations for clinical trialsJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 37Issue #:Start Page: 26End Page: 37Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2015.09.018Best OA location URL: https://doi.org/10.1016/j.neurobiolaging.2015.09.018Citation Count: 45
-
OPENTitle: Which figure copy test is more sensitive for cognitive impairment in Parkinson's disease: Wire cube or interlocking pentagons?Journal Name: Clinical Neurology and NeurosurgeryPublisher: Elsevier BVVol: 139Issue #:Start Page: 244End Page: 246Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.clineuro.2015.10.019Best OA location URL: https://europepmc.org/articles/pmc5792072?pdf=renderCitation Count: 9
-
OPENTitle: Clinimetric Analysis of the Motor Section of the Progressive Supranuclear Palsy Rating Scale: Reliability and Factor AnalysisJournal Name: Movement Disorders Clinical PracticePublisher: WileyVol: 3Issue #: 1Start Page: 65End Page: 67Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mdc3.12243Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mdc3.12243Citation Count: 9
-
RESTRICTEDTitle: Clinical and scientific perspectives on movement disorders: Stanley Fahn's contributionsJournal Name: Movement DisordersPublisher: WileyVol: 30Issue #: 14Start Page: 1862End Page: 1869Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/mds.26445Citation Count: 6
-
OPENTitle: Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotypingJournal Name: Nature ProtocolsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 11Start Page: 1860End Page: 1896Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nprot.2015.122Best OA location URL: https://europepmc.org/articles/pmc4917295?pdf=renderCitation Count: 252
-
OPENTitle: Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1Journal Name: The EMBO JournalPublisher: Springer Science and Business Media LLCVol: 34Issue #: 22Start Page: 2840End Page: 2861Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.15252/embj.201591593Best OA location URL: https://doi.org/10.15252/embj.201591593Citation Count: 171
-
OPENTitle: Parkinson disease and incidental Lewy body diseaseJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 85Issue #: 19Start Page: 1670End Page: 1679Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0000000000002102Best OA location URL: https://europepmc.org/articles/pmc4653112?pdf=renderCitation Count: 100
-
OPENTitle: O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's diseaseJournal Name: Nature ChemistryPublisher: Springer Science and Business Media LLCVol: 7Issue #: 11Start Page: 913End Page: 920Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nchem.2361Best OA location URL: https://europepmc.org/articles/pmc4618406?pdf=renderCitation Count: 253
-
OPENTitle: Stress Granules Modulate SYK to Cause Microglial Cell Dysfunction in Alzheimer's DiseaseJournal Name: EBioMedicinePublisher: Elsevier BVVol: 2Issue #: 11Start Page: 1785End Page: 1798Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.ebiom.2015.09.053Best OA location URL: http://www.ebiomedicine.com/article/S2352396415301687/pdfCitation Count: 50
-
OPENTitle: Isolating Visual and Proprioceptive Components of Motor Sequence Learning in ASDJournal Name: Autism ResearchPublisher: WileyVol: 9Issue #: 5Start Page: 563End Page: 569Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/aur.1537Best OA location URL: https://europepmc.org/articles/pmc4941622?pdf=renderCitation Count: 34
-
OPENTitle: The NINDS Parkinson's disease biomarkers programJournal Name: Movement DisordersPublisher: WileyVol: 31Issue #: 6Start Page: 915End Page: 923Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26438Best OA location URL: https://europepmc.org/articles/pmc4824671?pdf=renderCitation Count: 99
-
OPENTitle: Peripheral Biomarkers of Parkinson’s Disease Progression and Pioglitazone EffectsJournal Name: Journal of Parkinson's DiseasePublisher: SAGE PublicationsVol: 5Issue #: 4Start Page: 731End Page: 736Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3233/jpd-150666Best OA location URL: https://europepmc.org/articles/pmc5061495?pdf=renderCitation Count: 29
- Variants in GBA , SNCA , and MAPT influence Parkinson disease risk, age at onset, and progression2015OPENTitle: Variants in GBA , SNCA , and MAPT influence Parkinson disease risk, age at onset, and progressionJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 37Issue #:Start Page: 209.e1End Page: 209.e7Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2015.09.014Best OA location URL: https://europepmc.org/articles/pmc4688052?pdf=renderCitation Count: 103
-
RESTRICTEDTitle: Mitochondrial dynamics and viral infections: A close nexusJournal Name: Biochimica et Biophysica Acta (BBA) - Molecular Cell ResearchPublisher: Elsevier BVVol: 1853Issue #: 10Start Page: 2822End Page: 2833Publication Date:Open Access(OA) Status: RESTRICTEDLicense: publisher-specific-oaDOI - Digital Object Identifier: 10.1016/j.bbamcr.2014.12.040Best OA location URL: https://doi.org/10.1016/j.bbamcr.2014.12.040Citation Count: 145
-
RESTRICTEDTitle: Regeneration through Reprogramming Adult Cell Identity in VivoJournal Name: The American Journal of PathologyPublisher: Elsevier BVVol: 185Issue #: 10Start Page: 2619End Page: 2628Publication Date:Open Access(OA) Status: RESTRICTEDLicense: publisher-specific-oaDOI - Digital Object Identifier: 10.1016/j.ajpath.2015.02.025Best OA location URL: http://ajp.amjpathol.org/article/S0002944015002588/pdfCitation Count: 15
-
OPENTitle: Deep Brain Stimulation in a Case of Mitochondrial DiseaseJournal Name: Movement Disorders Clinical PracticePublisher: WileyVol: 3Issue #: 2Start Page: 139End Page: 145Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mdc3.12241Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mdc3.12241Citation Count: 9
-
OPENTitle: Fibroblast Biomarkers of Sporadic Parkinson’s Disease and LRRK2 Kinase InhibitionJournal Name: Molecular NeurobiologyPublisher: Springer Science and Business Media LLCVol: 53Issue #: 8Start Page: 5161End Page: 5177Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1007/s12035-015-9435-4Best OA location URL: https://link.springer.com/content/pdf/10.1007/s12035-015-9435-4.pdfCitation Count: 63
-
OPENTitle: Is the MC1R variant p.R160W associated with Parkinson's?Journal Name: Annals of NeurologyPublisher: WileyVol: 79Issue #: 1Start Page: 159End Page: 161Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.24527Best OA location URL: https://europepmc.org/articles/pmc4738170?pdf=renderCitation Count: 18
-
OPENTitle: Striatal and Cortical β‐Amyloidopathy and Cognition in Parkinson's DiseaseJournal Name: Movement DisordersPublisher: WileyVol: 31Issue #: 1Start Page: 111End Page: 117Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26369Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mds.26369Citation Count: 59
-
OPENTitle: Leucine‐rich repeat kinase 2 interacts with p21‐activated kinase 6 to control neurite complexity in mammalian brainJournal Name: Journal of NeurochemistryPublisher: WileyVol: 135Issue #: 6Start Page: 1242End Page: 1256Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1111/jnc.13369Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jnc.13369Citation Count: 66
-
OPENTitle: Activation of acid-sensing ion channels by localized proton transient reveals their role in proton signalingJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 5Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep14125Best OA location URL: https://www.nature.com/articles/srep14125.pdfCitation Count: 38
-
OPENTitle: A novel synthetic activator of Nurr1 induces dopaminergic gene expression and protects against 6-hydroxydopamine neurotoxicity in vitroJournal Name: Neuroscience LettersPublisher: Elsevier BVVol: 607Issue #:Start Page: 83End Page: 89Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neulet.2015.09.015Best OA location URL: https://europepmc.org/articles/pmc4631643?pdf=renderCitation Count: 45
-
OPENTitle: Feasibility of Virtual Research Visits in Fox Trial FinderJournal Name: Journal of Parkinson's DiseasePublisher: SAGE PublicationsVol: 5Issue #: 3Start Page: 505End Page: 515Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3233/jpd-150549Best OA location URL: https://content.iospress.com:443/download/journal-of-parkinsons-disease/jpd150549?id=journal-of-parkinsons-disease%2Fjpd150549Citation Count: 60
-
RESTRICTEDTitle: Immunotherapy in Parkinson’s Disease: Micromanaging Alpha-Synuclein AggregationJournal Name: Journal of Parkinson's DiseasePublisher: IOS PressVol: 5Issue #: 3Start Page: 413End Page: 424Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-by-ncDOI - Digital Object Identifier: 10.3233/jpd-150630Best OA location URL: https://content.iospress.com:443/download/journal-of-parkinsons-disease/jpd150630?id=journal-of-parkinsons-disease%2Fjpd150630Citation Count: 72
-
OPENTitle: Precompetitive Data Sharing as a Catalyst to Address Unmet Needs in Parkinson’s Disease 1Journal Name: Journal of Parkinson's DiseasePublisher: SAGE PublicationsVol: 5Issue #: 3Start Page: 581End Page: 594Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3233/jpd-150570Best OA location URL: https://content.iospress.com:443/download/journal-of-parkinsons-disease/jpd150570?id=journal-of-parkinsons-disease%2Fjpd150570Citation Count: 29
- REM sleep behavior disorder, as assessed by questionnaire, in G2019S LRRK2 mutation PD and carriers2015OPENTitle: REM sleep behavior disorder, as assessed by questionnaire, in G2019S LRRK2 mutation PD and carriersJournal Name: Movement DisordersPublisher: WileyVol: 30Issue #: 13Start Page: 1834End Page: 1839Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26413Best OA location URL: https://europepmc.org/articles/pmc4715645?pdf=renderCitation Count: 34
-
OPENTitle: Aberrant intracellular localization of H3k4me3 demonstrates an early epigenetic phenomenon in Alzheimer's diseaseJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 36Issue #: 12Start Page: 3121End Page: 3129Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2015.08.017Best OA location URL: https://europepmc.org/articles/pmc4838454?pdf=renderCitation Count: 54
-
OPENTitle: Dopaminergic, serotonergic, and noradrenergic deficits in Parkinson diseaseJournal Name: Annals of Clinical and Translational NeurologyPublisher: WileyVol: 2Issue #: 10Start Page: 949End Page: 959Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/acn3.246Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.246Citation Count: 171
-
OPENTitle: Longitudinal study of normal cognition in Parkinson diseaseJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 85Issue #: 15Start Page: 1276End Page: 1282Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0000000000002001Best OA location URL: https://europepmc.org/articles/pmc4617168?pdf=renderCitation Count: 225
-
OPENTitle: Functional Role of the Disulfide Isomerase ERp57 in Axonal RegenerationJournal Name: PLOS ONEPublisher: Public Library of Science (PLoS)Vol: 10Issue #: 9Start Page: e0136620End Page: e0136620Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0136620Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0136620&type=printableCitation Count: 52
-
OPENTitle: Improvement of dyskinesias withl-dopa infusion in advanced Parkinson's diseaseJournal Name: Acta Neurologica ScandinavicaPublisher: WileyVol: 133Issue #: 6Start Page: 451End Page: 458Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/ane.12483Best OA location URL: https://doi.org/10.1111/ane.12483Citation Count: 26
-
OPENTitle: Sustained attention training reduces spatial bias in Parkinson’s disease: a pilot case seriesJournal Name: NeurocasePublisher: Informa UK LimitedVol: 22Issue #: 2Start Page: 179End Page: 186Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1080/13554794.2015.1088035Best OA location URL: https://europepmc.org/articles/pmc4949393?pdf=renderCitation Count: 12
-
RESTRICTEDTitle: Differential contribution of Ih to the integration of excitatory synaptic inputs in substantia nigra pars compacta and ventral tegmental area dopaminergic neuronsJournal Name: European Journal of NeurosciencePublisher: WileyVol: 42Issue #: 9Start Page: 2699End Page: 2706Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1111/ejn.13066Citation Count: 30
-
OPENTitle: Large-scale assessment of polyglutamine repeat expansions in Parkinson diseaseJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 85Issue #: 15Start Page: 1283End Page: 1292Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0000000000002016Best OA location URL: https://europepmc.org/articles/pmc4617164?pdf=renderCitation Count: 27
-
OPENTitle: Longitudinal Study of Gray Matter Changes in Parkinson DiseaseJournal Name: American Journal of NeuroradiologyPublisher: American Society of Neuroradiology (ASNR)Vol: 36Issue #: 12Start Page: 2219End Page: 2226Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3174/ajnr.a4447Best OA location URL: http://www.ajnr.org/content/ajnr/36/12/2219.full.pdfCitation Count: 63
-
OPENTitle: Network structure of brain atrophy in de novo Parkinson's diseaseJournal Name: eLifePublisher: eLife Sciences Publications, LtdVol: 4Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.7554/elife.08440Best OA location URL: https://doi.org/10.7554/elife.08440Citation Count: 223
-
RESTRICTEDTitle: A novel retinal biomarker for Parkinson's disease: Quantifying the foveal pit with optical coherence tomographyJournal Name: Movement DisordersPublisher: WileyVol: 30Issue #: 12Start Page: 1692End Page: 1695Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/mds.26411Citation Count: 22
-
OPENTitle: Oligomeric α‐synuclein and β‐amyloid variants as potential biomarkers for Parkinson's and Alzheimer's diseasesJournal Name: European Journal of NeurosciencePublisher: WileyVol: 43Issue #: 1Start Page: 3End Page: 16Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/ejn.13056Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ejn.13056Citation Count: 66
-
RESTRICTEDTitle: Bypassing the blood–brian barrier using established skull base reconstruction techniquesJournal Name: World Journal of Otorhinolaryngology - Head and Neck SurgeryPublisher: WileyVol: 1Issue #: 1Start Page: 11End Page: 16Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.wjorl.2015.09.001Best OA location URL: https://doi.org/10.1016/j.wjorl.2015.09.001Citation Count: 7
- CSF β-Amyloid 1-42 Predicts Progression to Cognitive Impairment in Newly Diagnosed Parkinson Disease2015OPENTitle: CSF β-Amyloid 1-42 Predicts Progression to Cognitive Impairment in Newly Diagnosed Parkinson DiseaseJournal Name: Journal of Molecular NeurosciencePublisher: Springer Science and Business Media LLCVol: 58Issue #: 1Start Page: 88End Page: 92Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s12031-015-0647-xBest OA location URL: https://europepmc.org/articles/pmc4738011?pdf=renderCitation Count: 89
-
RESTRICTEDTitle: ER stress signaling and neurodegeneration: At the intersection between Alzheimer's disease and Prion-related disordersJournal Name: Virus ResearchPublisher: Elsevier BVVol: 207Issue #:Start Page: 69End Page: 75Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.virusres.2014.12.018Citation Count: 27
-
RESTRICTEDTitle: Interactions between misfolded protein oligomers and membranes: A central topic in neurodegenerative diseases?Journal Name: Biochimica et Biophysica Acta (BBA) - BiomembranesPublisher: Elsevier BVVol: 1848Issue #: 9Start Page: 1897End Page: 1907Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.bbamem.2015.01.018Citation Count: 94
-
RESTRICTEDTitle: The D3 dopamine receptor: From structural interactions to functionJournal Name: European NeuropsychopharmacologyPublisher: Elsevier BVVol: 25Issue #: 9Start Page: 1462End Page: 1469Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.euroneuro.2014.11.021Citation Count: 38
-
OPENTitle: tranSMART Foundation Datathon 1.0: The cross neurodegenerative diseases challengeJournal Name: Applied & Translational GenomicsPublisher: Elsevier BVVol: 6Issue #:Start Page: 42End Page: 44Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.atg.2015.08.004Best OA location URL: https://doi.org/10.1016/j.atg.2015.08.004Citation Count: 8
-
RESTRICTEDTitle: Thalamic deep brain stimulation for drug-induced tremorJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 21Issue #: 11Start Page: 1369End Page: 1370Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2015.08.033Citation Count: 7
-
OPENTitle: Generation of SNCA Cell Models Using Zinc Finger Nuclease (ZFN) Technology for Efficient High-Throughput Drug ScreeningJournal Name: PLOS ONEPublisher: Public Library of Science (PLoS)Vol: 10Issue #: 8Start Page: e0136930End Page: e0136930Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0136930Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0136930&type=printableCitation Count: 21
-
OPENTitle: Non-exercise physical activity attenuates motor symptoms in Parkinson disease independent from nigrostriatal degenerationJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 21Issue #: 10Start Page: 1227End Page: 1231Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2015.08.027Best OA location URL: https://europepmc.org/articles/pmc4587298?pdf=renderCitation Count: 23
-
RESTRICTEDTitle: Transcriptional mutagenesis by 8-oxodG in α-synuclein aggregation and the pathogenesis of Parkinson’s diseaseJournal Name: Experimental & Molecular MedicinePublisher: Springer Science and Business Media LLCVol: 47Issue #: 8Start Page: e179End Page: e179Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1038/emm.2015.54Best OA location URL: https://www.nature.com/articles/emm201554.pdfCitation Count: 27