4201 - 4250 of 8808 Results
Title
Year
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OPENTitle: Integrative Pathway-Based Approach for Genome-Wide Association Studies: Identification of New Pathways for Rheumatoid Arthritis and Type 1 DiabetesJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 8Issue #: 10Start Page: e78577End Page: e78577Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0078577Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0078577&type=printableCitation Count: 10
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OPENTitle: Permeabilization of the Blood-Brain Barrier via Mucosal Engrafting: Implications for Drug Delivery to the BrainJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 8Issue #: 4Start Page: e61694End Page: e61694Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0061694Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0061694&type=printableCitation Count: 37
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OPENTitle: Human α4β2 Nicotinic Acetylcholine Receptor as a Novel Target of Oligomeric α-SynucleinJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 8Issue #: 2Start Page: e55886End Page: e55886Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0055886Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0055886&type=printableCitation Count: 13
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OPENTitle: The PINK1 p.I368N mutation affects protein stability and ubiquitin kinase activityJournal Name: Molecular NeurodegenerationPublisher: Springer Science and Business Media LLCVol: 12Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13024-017-0174-zBest OA location URL: https://molecularneurodegeneration.biomedcentral.com/track/pdf/10.1186/s13024-017-0174-zCitation Count: 76
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OPENTitle: Identification of candidate genes for familial early-onset essential tremorJournal Name: European Journal of Human GeneticsPublisher: Springer Science and Business Media LLCVol: 24Issue #: 7Start Page: 1009End Page: 1015Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/ejhg.2015.228Best OA location URL: https://www.nature.com/articles/ejhg2015228.pdfCitation Count: 39
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OPENTitle: A novel resource for studying function and dysfunction of α-synuclein: mouse lines for modulation of endogenous Snca gene expressionJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 5Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep16615Best OA location URL: https://www.nature.com/articles/srep16615.pdfCitation Count: 25
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OPENTitle: Bid signal pathway components are identified in the temporal cortex with Parkinson diseaseJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 79Issue #: 17Start Page: 1767End Page: 1773Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0b013e3182703f76Best OA location URL: https://n.neurology.org/content/neurology/79/17/1767.full.pdfCitation Count: 17
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OPENTitle: Markers of impaired motor and cognitive volition in Parkinson's disease: Correlates of dopamine dysregulation syndrome, impulse control disorder, and dyskinesiasJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 47Issue #:Start Page: 50End Page: 56Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2017.11.338Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5803355Citation Count: 19
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OPENTitle: Biochemical Characterization of Highly Purified Leucine-Rich Repeat Kinases 1 and 2 Demonstrates Formation of HomodimersJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 7Issue #: 8Start Page: e43472End Page: e43472Publication Date:Open Access(OA) Status: OPENLicense: cc0DOI - Digital Object Identifier: 10.1371/journal.pone.0043472Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0043472&type=printableCitation Count: 102
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OPENTitle: Neuroprotective activities of regulatory T cellsJournal Name: Trends in Molecular MedicinePublisher: Elsevier BVVol: 17Issue #: 12Start Page: 687End Page: 688Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.molmed.2011.08.005Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5892451Citation Count: 51
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RESTRICTEDTitle: Dopamine Release at Individual Presynaptic Terminals Visualized with FFNsJournal Name: Journal of Visualized ExperimentsPublisher: MyJove CorporationVol:Issue #: 30Start Page:End Page:Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.3791/1562Citation Count: 10
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OPENTitle: Cross-Sectional and Longitudinal Relationships Between Cerebrospinal Fluid Biomarkers and Cognitive Function in People Without Cognitive Impairment From Across the Adult Life SpanJournal Name: JAMA NeurologyPublisher: American Medical Association (AMA)Vol: 71Issue #: 6Start Page: 742End Page: 742Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/jamaneurol.2014.445Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4051849Citation Count: 39
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OPENTitle: Striatal Pleiotrophin Overexpression Provides Functional and Morphological Neuroprotection in the 6-Hydroxydopamine ModelJournal Name: Molecular TherapyPublisher: Elsevier BVVol: 20Issue #: 3Start Page: 544End Page: 554Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1038/mt.2011.216Best OA location URL: http://www.cell.com/article/S1525001616305111/pdfCitation Count: 31
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OPENTitle: Changes in CD200 and intercellular adhesion molecule-1 (ICAM-1) levels in brains of Lewy body disorder cases are associated with amounts of Alzheimer's pathology not α-synuclein pathologyJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 54Issue #:Start Page: 175End Page: 186Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2017.03.007Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5862548Citation Count: 31
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OPENTitle: A scan without evidence is not evidence of absence: Scans without evidence of dopaminergic deficit in a symptomatic leucine‐rich repeat kinase 2 mutation carrierJournal Name: Movement DisordersPublisher: WileyVol: 31Issue #: 3Start Page: 405End Page: 409Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26450Best OA location URL: http://doi.org/10.1002/mds.26450Citation Count: 18
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OPENTitle: Hereditary diffuse leukoencephalopathy with spheroids with phenotype of primary progressive multiple sclerosisJournal Name: European Journal of NeurologyPublisher: WileyVol: 22Issue #: 2Start Page: 328End Page: 333Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/ene.12572Best OA location URL: http://doi.org/10.1111/ene.12572Citation Count: 45
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OPENTitle: Naltrexone for impulse control disorders in Parkinson diseaseJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 83Issue #: 9Start Page: 826End Page: 833Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0000000000000729Best OA location URL: https://n.neurology.org/content/neurology/83/9/826.full.pdfCitation Count: 90
- Cognitive Profiles in Parkinson’s Disease and Their Relation to Dementia: A Data-Driven Approach2012OPENTitle: Cognitive Profiles in Parkinson’s Disease and Their Relation to Dementia: A Data-Driven ApproachJournal Name: International Journal of Alzheimer's DiseasePublisher: Hindawi LimitedVol: 2012Issue #:Start Page: 1End Page: 11Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1155/2012/910757Best OA location URL: https://downloads.hindawi.com/journals/ijad/2012/910757.pdfCitation Count: 12
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OPENTitle: Declining Quality of Life in Parkinson Disease Before and After DiagnosisJournal Name: Journal of Parkinson's DiseasePublisher: SAGE PublicationsVol: 2Issue #: 2Start Page: 153End Page: 160Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3233/jpd-2012-12083Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3744127Citation Count: 12
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OPENTitle: Coffee, ADORA2A, and CYP1A2: the caffeine connection in Parkinson’s diseaseJournal Name: European Journal of NeurologyPublisher: WileyVol: 18Issue #: 5Start Page: 756End Page: 765Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/j.1468-1331.2011.03353.xCitation Count: 112
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OPENTitle: KIF6 719Arg Carrier Status Association with Homocysteine and C-Reactive Protein in Amnestic Mild Cognitive Impairment and Alzheimer’s Disease PatientsJournal Name: International Journal of Alzheimer's DiseasePublisher: WileyVol: 2013Issue #:Start Page: 1End Page: 6Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1155/2013/242303Best OA location URL: https://downloads.hindawi.com/journals/ijad/2013/242303.pdfCitation Count: 3
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OPENTitle: Reorganization of corticostriatal circuits in healthy G2019S LRRK2 carriersJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 84Issue #: 4Start Page: 399End Page: 406Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0000000000001189Best OA location URL: https://n.neurology.org/content/neurology/84/4/399.full.pdfCitation Count: 76
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OPENTitle: Proteomic Analysis of Alzheimers Disease Cerebrospinal Fluid from Neuropathologically Diagnosed SubjectsJournal Name: Current Alzheimer ResearchPublisher: Bentham Science Publishers Ltd.Vol: 6Issue #: 4Start Page: 399End Page: 406Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.2174/156720509788929318Best OA location URL: http://www.eurekaselect.com/article/29748Citation Count: 33
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OPENTitle: Anosognosia increases caregiver burden in mild cognitive impairmentJournal Name: International Journal of Geriatric PsychiatryPublisher: WileyVol: 31Issue #: 7Start Page: 799End Page: 808Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/gps.4394Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8483618Citation Count: 48
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OPENTitle: Additional rare variant analysis in Parkinson’s disease cases with and without known pathogenic mutations: evidence for oligogenic inheritanceJournal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol:Issue #:Start Page: ddw348End Page: ddw348Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1093/hmg/ddw348Best OA location URL: https://academic.oup.com/hmg/article-pdf/25/24/5483/10408585/ddw348.pdfCitation Count: 54
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OPENTitle: Increased Alzheimer’s Disease Neuropathology is Associated with Type 2 Diabetes and ApoE ε4 Carrier StatusJournal Name: Current Alzheimer ResearchPublisher: Bentham Science Publishers Ltd.Vol: 10Issue #: 6Start Page: 654End Page: 659Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.2174/15672050113109990006Citation Count: 62
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OPENTitle: Functional Brain Activity Relates to 0–3 and 3–8 Hz Force Oscillations in Essential TremorJournal Name: Cerebral CortexPublisher: Oxford University Press (OUP)Vol: 25Issue #: 11Start Page: 4191End Page: 4202Publication Date:Open Access(OA) Status: OPENLicense: public-domainDOI - Digital Object Identifier: 10.1093/cercor/bhu142Best OA location URL: https://academic.oup.com/cercor/article-pdf/25/11/4191/7001061/bhu142.pdfCitation Count: 79
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OPENTitle: Management of Deep Brain Stimulator Battery Failure: Battery Estimators, Charge Density, and Importance of Clinical SymptomsJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 8Issue #: 3Start Page: e58665End Page: e58665Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0058665Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0058665&type=printableCitation Count: 73
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OPENTitle: Parkinson Disease Affects Peripheral Sensory Nerves in the PharynxJournal Name: Journal of Neuropathology & Experimental NeurologyPublisher: Oxford University Press (OUP)Vol: 72Issue #: 7Start Page: 614End Page: 623Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1097/nen.0b013e3182965886Best OA location URL: https://academic.oup.com/jnen/article-pdf/72/7/614/9562662/72-7-614.pdfCitation Count: 149
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OPENTitle: In vitro-differentiated neural cell cultures progress towards donor-identical brain tissueJournal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 22Issue #: 17Start Page: 3534End Page: 3546Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/hmg/ddt208Best OA location URL: http://doi.org/10.1093/hmg/ddt208Citation Count: 23
- Manual-Protocol Inspired Technique for Improving Automated MR Image Segmentation during Label Fusion2016OPENTitle: Manual-Protocol Inspired Technique for Improving Automated MR Image Segmentation during Label FusionJournal Name: Frontiers in NeurosciencePublisher: Frontiers Media SAVol: 10Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnins.2016.00325Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnins.2016.00325/pdfCitation Count: 12
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OPENTitle: High regulatability favors genetic selection in SLC18A2 , a vesicular monoamine transporter essential for lifeJournal Name: The FASEB JournalPublisher: WileyVol: 24Issue #: 7Start Page: 2191End Page: 2200Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1096/fj.09-140368Citation Count: 16
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OPENTitle: Modulation of Neuronal Survival Factor MEF2 by Kinases in Parkinson’s DiseaseJournal Name: Frontiers in PhysiologyPublisher: Frontiers Media SAVol: 3Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fphys.2012.00171Best OA location URL: https://www.frontiersin.org/articles/10.3389/fphys.2012.00171/pdfCitation Count: 23
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OPENTitle: ALS-FTD Complex Disorder due to <b><i>C9ORF72</i></b> Gene Mutation: Description of First Polish FamilyJournal Name: European NeurologyPublisher: S. Karger AGVol: 72Issue #: 1-2Start Page: 64End Page: 71Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1159/000362267Best OA location URL: https://karger.com/ene/article-pdf/72/1-2/64/2724525/000362267.pdfCitation Count: 1
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OPENTitle: GTP binding controls complex formation by the human ROCO protein MASL1Journal Name: The FEBS JournalPublisher: WileyVol: 281Issue #: 1Start Page: 261End Page: 274Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1111/febs.12593Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/febs.12593Citation Count: 13
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OPENTitle: Racial differences may influence the role of cholecystokinin polymorphisms in Parkinson's disease hallucinationsJournal Name: Movement DisordersPublisher: WileyVol: 26Issue #: 9Start Page: 1781End Page: 1783Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.23655Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3142314Citation Count: 19
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OPENTitle: Modulation of intracellular calcium signaling by microRNA-34a-5pJournal Name: Cell Death & DiseasePublisher: Springer Science and Business Media LLCVol: 9Issue #: 10Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41419-018-1050-7Best OA location URL: https://www.nature.com/articles/s41419-018-1050-7.pdfCitation Count: 28
- Dentate nucleus iron deposition is a potential biomarker for tremor‐dominant Parkinson's disease2016OPENTitle: Dentate nucleus iron deposition is a potential biomarker for tremor‐dominant Parkinson's diseaseJournal Name: NMR in BiomedicinePublisher: WileyVol: 30Issue #: 4Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/nbm.3554Best OA location URL: http://doi.org/10.1002/nbm.3554Citation Count: 54
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OPENTitle: Parkinson disease in Gaucher diseaseJournal Name: Journal of Clinical Movement DisordersPublisher: Springer Science and Business Media LLCVol: 4Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s40734-017-0054-2Best OA location URL: https://doi.org/10.1186/s40734-017-0054-2Citation Count: 14
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OPENTitle: A Genome‐wide Scan in an Amish Pedigree with ParkinsonismJournal Name: Annals of Human GeneticsPublisher: WileyVol: 72Issue #: 5Start Page: 621End Page: 629Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/j.1469-1809.2008.00452.xBest OA location URL: http://doi.org/10.1111/j.1469-1809.2008.00452.xCitation Count: 12
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RESTRICTEDTitle: Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson’s diseaseJournal Name: Journal of Neuroscience ResearchPublisher: WileyVol: 97Issue #: 3Start Page: 346End Page: 361Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/jnr.24363Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/11863348Citation Count: 27
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OPENTitle: Reduced striatal tyrosine hydroxylase in incidental Lewy body diseaseJournal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 115Issue #: 4Start Page: 445End Page: 451Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s00401-007-0313-7Best OA location URL: http://doi.org/10.1007/s00401-007-0313-7Citation Count: 125
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OPENTitle: Neuronal gene expression correlates of Parkinson's disease with dementiaJournal Name: Movement DisordersPublisher: WileyVol: 23Issue #: 11Start Page: 1588End Page: 1595Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.22184Best OA location URL: http://doi.org/10.1002/mds.22184Citation Count: 48
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OPENTitle: Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian miceJournal Name: Journal of Clinical InvestigationPublisher: American Society for Clinical InvestigationVol: 118Issue #: 1Start Page: 149End Page: 160Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1172/jci32273Best OA location URL: http://doi.org/10.1172/JCI32273Citation Count: 179
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OPENTitle: Are there differences in cerebral white matter lesion burdens between Parkinson’s disease patients with or without dementia?Journal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 119Issue #: 1Start Page: 147End Page: 149Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s00401-009-0620-2Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2928051Citation Count: 46
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OPENTitle: Variation in the oxytocin receptor gene is associated with increased risk for anxiety, stress and depression in individuals with a history of exposure to early life stressJournal Name: Journal of Psychiatric ResearchPublisher: Elsevier BVVol: 59Issue #:Start Page: 93End Page: 100Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.jpsychires.2014.08.021Best OA location URL: http://doi.org/10.1016/j.jpsychires.2014.08.021Citation Count: 90
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OPENTitle: Characterization of RNA isolated from eighteen different human tissues: results from a rapid human autopsy programJournal Name: Cell and Tissue BankingPublisher: Springer Science and Business Media LLCVol: 17Issue #: 3Start Page: 361End Page: 375Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s10561-016-9555-8Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5026224Citation Count: 69
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OPENTitle: Impact of Alzheimer's Disease, Lewy Body and Vascular Co-Pathologies on Clinical Transition to Dementia in a National Autopsy CohortJournal Name: Dementia and Geriatric Cognitive DisordersPublisher: S. Karger AGVol: 42Issue #: 1-2Start Page: 106End Page: 116Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1159/000448243Best OA location URL: http://doi.org/10.1159/000448243Citation Count: 18
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OPENTitle: Evaluation of the D3 dopamine receptor selective agonist/partial agonist PG01042 on l-dopa dependent animal involuntary movements in ratsJournal Name: NeuropharmacologyPublisher: Elsevier BVVol: 60Issue #: 2-3Start Page: 284End Page: 294Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neuropharm.2010.09.011Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3820002Citation Count: 21
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OPENTitle: Droxidopa and Reduced Falls in a Trial of Parkinson Disease Patients With Neurogenic Orthostatic HypotensionJournal Name: Clinical NeuropharmacologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 39Issue #: 5Start Page: 220End Page: 226Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1097/wnf.0000000000000168Best OA location URL: https://doi.org/10.1097/wnf.0000000000000168Citation Count: 60