The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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ASAP CRN Competitive Renewal Opportunity, 2024IMPACT-PD: Implications of Polyamine and Glucosylceramide Transport in Parkinson’s Disease
Study Rationale: Mutations in the genes ATP13A2, GBA1 and ATP10B trigger Parkinson’s disease (PD) and cause dysfunction of lysosomes, the recycling compartments of the cell. These genes regulate the...
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ASAP CRN Competitive Renewal Opportunity, 2024Studying the Pathogenesis of Parkinson’s Disease Via Single-cell Analysis of Human Brain and Gut Cells: A Basis for Clinical Translation
Study Rationale: More than 100 regions of the chromosomes that we inherit from our parents show differences in DNA sequence between people with and without Parkinson’s disease (PD). Furthermore, as we...
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ASAP CRN Competitive Renewal Opportunity, 2024Examining the Mechanisms of Mitochondrial Damage Control by PINK1 and Parkin
Study Rationale: Mutations in PINK1 and Parkin genes underlie some forms of Parkinson’s disease (PD). The protein products of these genes are responsible for the maintenance and degradation of...
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ASAP CRN Competitive Renewal Opportunity, 2024Circuit Mechanisms for Dopamine Neuron Vulnerability and Resilience in Parkinson’s Disease
Study Rationale: Dopamine neurons are particularly vulnerable to death in Parkinson’s disease (PD), and their loss is one of the main causes of movement problems in people with PD. Dopamine neurons...
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ASAP CRN Competitive Renewal Opportunity, 2024Studying the Circuit Dysfunction Underlying Motor and Sleep Deficits in a Progressive Preclinical Model of Parkinson’s Disease
Study Rationale: Parkinson’s disease (PD) begins decades before it compromises an individual’s ability to move about in the world and sleep through the night. Understanding how the dysfunction of...
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ASAP CRN Competitive Renewal Opportunity, 2024Parkinson5D: Deconstructing Disease Mechanisms Across Cells, Space and Progression
Study Rationale: Although thousands of DNA variants are linked to Parkinson’s disease (PD), their exact functions are unknown. These variants are in the “dark matter” of our genome and do not lead to...
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Our funding programs support basic, translational and clinical research from academia and industry.