The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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ASAP CRN Competitive Renewal Opportunity, 2024Studying the Cortical Pathophysiology of Parkinsonism
Study Rationale: Activity changes in nerve cells in the brain’s cerebral cortex are central to Parkinson’s disease (PD). However, which specific cell types are affected, and how and when their...
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ASAP CRN Competitive Renewal Opportunity, 2024Understanding and Manipulating Cellular and Circuit-level Vulnerability to Neurodegeneration in Parkinson’s Disease
Study Rationale: Many people with Parkinson’s disease (PD) develop untreatable cognitive symptoms due to changes in the brain’s cerebral cortex. These symptoms, which include problems with attention...
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ASAP CRN Competitive Renewal Opportunity, 2024Activation of Transposable Elements as a Trigger of Neuroinflammation in Parkinson’s Disease
Study Rationale: Inflammation is a common event in neurodegenerative diseases such as Parkinson's disease (PD), although its source remains unclear. Many different factors can potentially trigger...
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ASAP CRN Competitive Renewal Opportunity, 2024Redefining the Pathophysiological Mechanisms of Parkinson’s Disease in the Context of Heterogeneous Neuronsl Subtypes in the Substantia Nigr
Study Rationale: The motor symptoms of Parkinson's disease (PD) result from the degeneration of dopamine-producing neurons in a brain area called the substantia nigra pars compacta (SNc). Recent...
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ASAP CRN Competitive Renewal Opportunity, 2024Studying Basal Ganglia Networks in Parkinson's Disease
Study Rationale: People with Parkinson's disease (PD) have long been known to display remarkable motor abilities under special circumstances, such as situations that involve strong emotions or stress...
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ASAP CRN Competitive Renewal Opportunity, 2024Mapping the LRRK2 Signaling Pathway and Uncovering Its Interplay with Other Molecular Components of Parkinson’s Disease
Study Rationale: Genetic mutations that lead to the activation of the enzyme LRRK2 are a major cause of inherited Parkinson's disease (PD). Combining the expertise of our four laboratories, we will...
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Our funding programs support basic, translational and clinical research from academia and industry.