The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Novel PET Tracer Development Program, 2022Discovery of Novel Radiolabeled Tracers for Imaging Microglia Associated with Neuroinflammation in Parkinson’s disease
Study Rationale: Parkinson´s disease (PD) is associated with neuroinflammation and the activation of microglia, cells that belong to the brain’s immune system. A protein called Colony stimulating...
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Research Grant, 2022Longitudinal Endpoint Optimization to Provide an Assessment of Relevant Drugs in Parkinson’s Disease (LEOPARD-PD)
Study Rationale: The Parkinson’s Disease-Health Index (PD-HI) is a novel, disease specific patient-reported outcome (PRO) measure designed for use in clinical trials to track clinically meaningful...
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Research Resources Imaging Program, 2022Developing Actionable Machine Learning (AML) Methods for Diagnosing, Monitoring and Treating Parkinson’s Disease
Study Rationale: In today’s modern age of computational smart health, actionable machine learning (AML) methods automatically and progressively learn how to correctly answer queries about the state of...
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Biomarkers to Support Therapeutic Trials Program, 2022Identifying Biomarkers for a Mitochondrial Subtype of Parkinson’s Disease
Study Rationale: Increasing evidence suggests that the disorder we refer to as Parkinson’s disease (PD) might represent several diseases, each driven by different biological mechanisms. The...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2022Glucocerebrosidase Activation as a Therapeutic Strategy for Parkinson’s Disease
Study Rationale: Mutations in GBA1, the gene that encodes glucocerebrosidase (GCase), diminish GCase activity in an estimated 7 to 10% of people with Parkinson’s disease (PD). In addition, reduced...
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Research Grant, 2022Creation and Testing of a Combined Cognitive Score in Parkinson Disease
Study Rationale: Many different tests of memory and thinking are given to people with Parkinson’s disease (PD), but it is not clear how to use or combine these test scores to best detect early...
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Our funding programs support basic, translational and clinical research from academia and industry.