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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Novel PET Tracer Development Program, 2022
    Screening for PET Tracers that will Bind to the P2Y12 Receptor and Allow Monitoring of Microglia Activation During Neuroinflammation

    Study Rationale: One of the hallmarks of Parkinson’s disease (PD) is neuroinflammation. During this dynamic process, the brain’s immune cells, called microglia, become activated and can either prolong...

  • Research Grant, 2023
    Mobility Matters: A Mobilise-D Extension Study

    Study Rationale: Mobility, the ability to physically move around, is vitally important and key to an individual’s independence. Although loss of mobility is a key feature in Parkinson’s disease (PD)...

  • Translational Pipeline Program, 2022
    Development of a Nurr1 Activator as a Novel Therapeutic for Parkinson’s Disease

    Study Rationale: Nurr1 is a protein that works in the nucleus of dopamine-producing nerve cells in the brain to keep these cells functioning normally. Emerging evidence suggests that impaired function...

  • Edmond J. Safra Movement Disorders Research Career Development Award, 2024
    Towards a Better Understanding of Treatment-refractory Gait Issues in Parkinson’s Disease

    Study Rationale: Freezing of gait (FOG) is a sudden arrest of gait despite the intention to continue walking, often while a person is turning, walking in a confined space or is in a situation that...

  • Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2024
    Preclinical Testing of Novel DBS Protocol for Long-Lasting Therapeutic Effects

    Study Rationale: Deep brain stimulation is an effective therapy for motor symptoms of late-stage Parkinson’s disease. It works like a pacemaker to interrupt abnormal patterns of brain activity that...

  • Therapeutic Pipeline Program, 2024
    Photoreceptor-directed Light Therapy in Parkinson’s Disease

    Study Rationale: Non-motor symptoms including sleep disturbances are common and enormously impact on the quality of life in people with Parkinson’s disease. Sleep disruption affects motor function and...

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