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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Seed Amplification Assay Innovation Program, 2025
    Quantification of Seed Competent Alpha-synuclein in Body Fluids

    Study Rationale: Seed amplification assays (SAA) are very effective in helping to diagnose Parkinson’s where the alpha-synuclein protein is involved. Using “spinal tap” fluid (CSF), SAA can tell if a...

  • Seed Amplification Assay Innovation Program, 2025
    Quantitative SAAs for Alpha-synuclein from Various Matrices

    Study Rationale: Currently existing seed amplification assays (SAAs) in which pathological protein clumps from patient samples are amplified such that they can be more easily detected for the...

  • T2T Validation - NOD2, 2025
    Using Knowledge Graphs to Predict NOD2 Directionality for Therapeutic Effect in Parkinson’s Disease

    Study Rationale: NOD2 is a key component of our immune defense system that detects invading pathogens and promotes their removal. Under healthy, ideal circumstances, NOD2 activity has a ‘Goldilocks...

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