The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Summer 2025 RFP: Accelerating Biological Understanding and Translational Approaches for PD Program - Biology, 2026Inhibition of Acid Ceramidase as a Therapy for GBA1-associated PD
Study Rationale:
Mutations in the GBA1 gene are the highest known risk factor for Parkinson’s disease (PD). In GBA1-associated PD (GBA1/PD), an enzyme in the lysosome of the cell...
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Spring 2025 RFA: Molecular MRI Biomarker Program, 2026Development of Next Generation Metabolic MR Imaging to Probe Molecular Mechanisms and Treatment Response in PD Patients Across Disease Stages
Study Rationale: There is a great unmet clinical need for more effective therapies to treat Parkinson Disease (PD). Successful clinical translation of new disease-modifying treatments can be...
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Spring 2025 RFA: Molecular MRI Biomarker Program, 2026MR Imaging of Immunomodulation in Parkinson’s Disease
Study Rationale:
Brain inflammation contributes to progression of Parkison’s Disease (PD), and drugs targeting inflammation are being developed as disease modifying treatments for PD...
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Research Grant, 2026Multimodal Machine Learning Models for Predicting Lewy Body Pathology Using Post-mortem Brain Data
Study Rationale:
Parkinson’s disease and Lewy body disease share many clinical and biological features, which makes it difficult to distinguish between them with current diagnostic tools. This lack of...
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T2T Validation - Endolysosomal Targets, 2026Toward an Atlas of Endolysosomal System Dysfunction with PD-associated Channels/Transporters
Study Rationale:
TMEM175 and ATP13A2 have been identified as risk genes for Parkinson’s disease. These proteins function to transport protons and polyamines through the lysosomal...
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Fall 2025 RFP: Data Advice To Action, 2026Multi-resolution Pathway-centric Biomarker Discovery for Parkinson’s Disease Diagnosis, Prognosis, Progression, and Treatment Recommendations
Study Rationale:
Parkinson’s disease (PD) is difficult to diagnose early and to distinguish from related synucleinopathies such as DLB and MSA. Although single-nucleus RNA sequencing...
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Our funding programs support basic, translational and clinical research from academia and industry.