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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Dopamine-Non-Responsive Symptoms of Parkinson's Disease, 2006
    Non-dopaminergic imaging biomarkers as tools for early PD - testing the Braak Hypothesis

    Many recent studies have suggested that we need to expand research in Parkinson's disease to study symptoms other than the typical motor symptoms of tremor, slowness of movements, stiffness, and...

  • Freezing of Gait Program, 2024
    Use of Neuromodulation to Relieve Gait Freezing in Parkinson’s Disease

    Study Rationale: Almost all individuals with Parkinson’s disease (PD) develop episodes of freezing of gait, which is a sudden inability to take a step while walking. Gait freezing can cause falls that...

  • Target Validation, 2011
    Preferential Targeting of Subpopulations of 5-HT1A Receptors

    Objective/Rationale:
    Although Parkinson's disease (PD) is primarily caused by dopamine dysfunction, function of serotonin (another neurotransmitter) is also affected. This suggests that serotonergic...

  • Developing and Validating Web-Based Clinical Assessments for, 2008
    Online Motor and Cognitive Analysis System

    Objective/Rationale:
    Despite advances in treatment approaches to Parkinson’s disease over the past 20 years, patient assessment methods have advanced little during this same period. Therefore, a...

  • Research Grant, 2021
    Bipolar Disorder and Parkinson’s Disease

    Study Rationale:
    Mood disorders are common in people with Parkinson’s disease (PD) and, in many cases, precede motor symptoms and diagnosis by years. The relationship between bipolar disorder and PD...

  • Therapeutic Pipeline Program, 2013
    Pre-clinical Evaluation of Neuroprotective Small Molecule Erythropoietin Receptor Agonists in the Treatment of Parkinson’s Disease

    Objective/Rationale:             
    Erythropoietin (EPO) receptor is present throughout the body and plays a role in both red blood cell production and tissue protection.  STATegics has discovered small...

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