The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Improved Biomarkers and Clinical Outcome Measures, 2016Identification of Tear Biomarkers for Individuals with Parkinson's Disease
Study Rationale:
Prior to the appearance of classic movement abnormalities like tremor and slowness, those with Parkinson's suffer from non-motor symptoms, such as altered function of the... -
Dopamine-Non-Responsive Symptoms of Parkinson's Disease, 2006Non-dopaminergic imaging biomarkers as tools for early PD - testing the Braak Hypothesis
Many recent studies have suggested that we need to expand research in Parkinson's disease to study symptoms other than the typical motor symptoms of tremor, slowness of movements, stiffness, and...
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Target Advancement Program, 2021Use of Therapeutic Nanoparticles to Inhibit Toxic Aggregation of Alpha-Synuclein
Study Rationale:
A hallmark of Parkinson’s disease (PD) is the abnormal accumulation of clumps of alpha-synuclein in nerve cells. These improperly folded protein clumps contribute to the symptoms of... -
Research Grant, 2023Leveraging Gene Expression Data to Redefine Parkinson’s Disease and the Pathways Driving Disease in Different Individuals
Study Rationale: People with Parkinson’s disease (PD) share some common problems, such as stiffness, slowness of movement and tremors. However, these symptoms vary in severity, and individuals often...
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Freezing of Gait Program, 2024Use of Neuromodulation to Relieve Gait Freezing in Parkinson’s Disease
Study Rationale: Almost all individuals with Parkinson’s disease (PD) develop episodes of freezing of gait, which is a sudden inability to take a step while walking. Gait freezing can cause falls that...
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Target Validation, 2011Preferential Targeting of Subpopulations of 5-HT1A Receptors
Objective/Rationale:
Although Parkinson's disease (PD) is primarily caused by dopamine dysfunction, function of serotonin (another neurotransmitter) is also affected. This suggests that serotonergic...
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Our funding programs support basic, translational and clinical research from academia and industry.