5101 - 5150 of 6295 Results
Title
Year
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OPENTitle: Cognitive Effects of Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease with GBA1 Pathogenic VariantsJournal Name: Movement DisordersPublisher: WileyVol: 38Issue #: 12Start Page: 2155End Page: 2162Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/mds.29647Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mds.29647Citation Count: 11
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OPENTitle: Urinary incontinence‐related effects on functional connectivity circuits in persons with Parkinson's diseaseJournal Name: Neurourology and UrodynamicsPublisher: WileyVol: 42Issue #: 8Start Page: 1694End Page: 1701Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/nau.25258Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/nau.25258Citation Count: 2
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OPENTitle: tranSMART Foundation Datathon 1.0: The cross neurodegenerative diseases challengeJournal Name: Applied & Translational GenomicsPublisher: Elsevier BVVol: 6Issue #:Start Page: 42End Page: 44Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.atg.2015.08.004Best OA location URL: https://doi.org/10.1016/j.atg.2015.08.004Citation Count: 8
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OPENTitle: White matter hyperintensities are more highly associated with preclinical Alzheimer's disease than imaging and cognitive markers of neurodegenerationJournal Name: Alzheimer's & Dementia: Diagnosis, Assessment & Disease MonitoringPublisher: WileyVol: 4Issue #: 1Start Page: 18End Page: 27Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.dadm.2016.03.001Best OA location URL: https://doi.org/10.1016/j.dadm.2016.03.001Citation Count: 88
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OPENTitle: Beyond L-DOPA: hope for Parkinson’s treatment and diagnosisJournal Name: EBioMedicinePublisher: Elsevier BVVol: 23Issue #:Start Page: 1End Page: 1Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.ebiom.2017.09.009Best OA location URL: http://www.ebiomedicine.com/article/S2352396417303626/pdfCitation Count: 0
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OPENTitle: Structural and biochemical insights into lipid transport by VPS13 proteinsJournal Name: Journal of Cell BiologyPublisher: Rockefeller University PressVol: 221Issue #: 5Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1083/jcb.202202030Best OA location URL: https://doi.org/10.1083/jcb.202202030Citation Count: 55
- Mitochondrial function-associated genes underlie cortical atrophy in prodromal synucleinopathies2023OPENTitle: Mitochondrial function-associated genes underlie cortical atrophy in prodromal synucleinopathiesJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 146Issue #: 8Start Page: 3301End Page: 3318Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1093/brain/awad044Best OA location URL: https://academic.oup.com/brain/advance-article-pdf/doi/10.1093/brain/awad044/49329244/awad044.pdfCitation Count: 22
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OPENTitle: In vivoreduction of age-dependent neuromelanin accumulation mitigates features of Parkinson’s diseaseJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 146Issue #: 3Start Page: 1040End Page: 1052Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc, cc-by-ncDOI - Digital Object Identifier: 10.1093/brain/awac445Best OA location URL: https://academic.oup.com/brain/article-pdf/146/3/1040/49356347/awac445.pdfCitation Count: 24
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OPENTitle: The non-specific lethal complex regulates genes and pathways genetically linked to Parkinson’s diseaseJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 146Issue #: 12Start Page: 4974End Page: 4987Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc, cc-by-ncDOI - Digital Object Identifier: 10.1093/brain/awad246Best OA location URL: https://academic.oup.com/brain/advance-article-pdf/doi/10.1093/brain/awad246/51010946/awad246.pdfCitation Count: 5
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OPENTitle: Patient-specific models link neurotransmitter receptor mechanisms with motor and visuospatial axes of Parkinson’s diseaseJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 14Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41467-023-41677-wBest OA location URL: https://www.nature.com/articles/s41467-023-41677-w.pdfCitation Count: 16
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OPENTitle: Predicting cognitive decline in a low-dimensional representation of brain morphologyJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 13Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-023-43063-4Best OA location URL: https://www.nature.com/articles/s41598-023-43063-4.pdfCitation Count: 2
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OPENTitle: CYP1B1-RMDN2 Alzheimer’s disease endophenotype locus identified for cerebral tau PETJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 15Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s41467-024-52298-2Best OA location URL: https://doi.org/10.1038/s41467-024-52298-2Citation Count: 4
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OPENTitle: CXCR6 orchestrates brain CD8+ T cell residency and limits mouse Alzheimer’s disease pathologyJournal Name: Nature ImmunologyPublisher: Springer Science and Business Media LLCVol: 24Issue #: 10Start Page: 1735End Page: 1747Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/s41590-023-01604-zBest OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/11102766Citation Count: 115
- Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer2024OPENTitle: Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancerJournal Name: Nature MetabolismPublisher: Springer Science and Business Media LLCVol: 6Issue #: 9Start Page: 1695End Page: 1711Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s42255-024-01118-4Best OA location URL: https://doi.org/10.1038/s42255-024-01118-4Citation Count: 17
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OPENTitle: Contributions of network structure, chemoarchitecture and diagnostic categories to transitions between cognitive topographiesJournal Name: Nature Biomedical EngineeringPublisher: Springer Science and Business Media LLCVol: 8Issue #: 9Start Page: 1142End Page: 1161Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41551-024-01242-2Best OA location URL: https://doi.org/10.1038/s41551-024-01242-2Citation Count: 13
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OPENTitle: Modelling human neuronal catecholaminergic pigmentation in rodents recapitulates age-related neurodegenerative deficitsJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 15Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41467-024-53168-7Best OA location URL: https://www.nature.com/articles/s41467-024-53168-7.pdfCitation Count: 10
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OPENTitle: An interpretable deep learning framework identifies proteomic drivers of Alzheimer’s diseaseJournal Name: Frontiers in Cell and Developmental BiologyPublisher: Frontiers Media SAVol: 12Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fcell.2024.1379984Best OA location URL: https://doi.org/10.3389/fcell.2024.1379984Citation Count: 5
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OPENTitle: APOE contributes to longitudinal impulse control disorders progression in Parkinson’s diseaseJournal Name: BMC PsychiatryPublisher: Springer Science and Business Media LLCVol: 24Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1186/s12888-024-06084-5Best OA location URL: http://doi.org/10.1186/s12888-024-06084-5Citation Count: 0
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OPENTitle: SVA Regulation of Transposable Element Clustered Transcription within the Major Histocompatibility Complex Genomic Class II Region of the Parkinson’s Progression Markers InitiativeJournal Name: GenesPublisher: MDPI AGVol: 15Issue #: 9Start Page: 1185End Page: 1185Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3390/genes15091185Best OA location URL: https://doi.org/10.3390/genes15091185Citation Count: 2
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OPENTitle: A Novel MAG Variant Causes Hereditary Spastic Paraplegia in a Consanguineous Pakistani FamilyJournal Name: GenesPublisher: MDPI AGVol: 15Issue #: 9Start Page: 1203End Page: 1203Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-by, cc-byDOI - Digital Object Identifier: 10.3390/genes15091203Best OA location URL: http://doi.org/10.3390/genes15091203Citation Count: 1
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OPENTitle: Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer’s disease, restores synapse integrity and memory in a disease mouse modelJournal Name: eLifePublisher: eLife Sciences Publications, LtdVol: 12Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.7554/elife.89453Best OA location URL: https://elifesciences.org/articles/89453.bibCitation Count: 8
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OPENTitle: Surface‐Based Morphometry Analysis of the Cerebral Cortex in Patients With Probable Idiopathic Rapid Eye Movement Sleep Behavior DisorderJournal Name: Brain and BehaviorPublisher: WileyVol: 14Issue #: 10Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/brb3.70057Best OA location URL: https://doi.org/10.1002/brb3.70057Citation Count: 1
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OPENTitle: A novel super-resolution microscopy platform for cutaneous alpha-synuclein detection in Parkinson’s diseaseJournal Name: Frontiers in Molecular NeurosciencePublisher: Frontiers Media SAVol: 17Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnmol.2024.1431549Best OA location URL: https://doi.org/10.3389/fnmol.2024.1431549Citation Count: 1
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OPENTitle: LRRK2 kinase activity is necessary for development and regeneration in Nematostella vectensisJournal Name: Neural DevelopmentPublisher: Springer Science and Business Media LLCVol: 19Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-nd, cc-by-nc-ndDOI - Digital Object Identifier: 10.1186/s13064-024-00193-3Best OA location URL: https://doi.org/10.1186/s13064-024-00193-3Citation Count: 2
- Relationship between sex biases in gene expression and sex biases in autism and Alzheimer’s disease2024OPENTitle: Relationship between sex biases in gene expression and sex biases in autism and Alzheimer’s diseaseJournal Name: Biology of Sex DifferencesPublisher: Springer Science and Business Media LLCVol: 15Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13293-024-00622-2Best OA location URL: https://doi.org/10.1186/s13293-024-00622-2Citation Count: 9
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OPENTitle: Relationships of B12 and Homocysteine with Outcomes in the SURE-PD, SURE-PD3, and STEADY-PDIII TrialsJournal Name: Journal of Parkinson’s DiseasePublisher: SAGE PublicationsVol: 14Issue #: 6Start Page: 1243End Page: 1255Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.3233/jpd-240035Best OA location URL: https://doi.org/10.3233/jpd-240035Citation Count: 1
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OPENTitle: Staging of progressive supranuclear palsy-Richardson syndrome using MRI brain charts for the human lifespanJournal Name: Brain CommunicationsPublisher: Oxford University Press (OUP)Vol: 6Issue #: 2Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1093/braincomms/fcae055Best OA location URL: https://academic.oup.com/braincomms/advance-article-pdf/doi/10.1093/braincomms/fcae055/56720392/fcae055.pdfCitation Count: 6
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OPENTitle: Alzheimer Disease Biomarkers: Moving from CSF to Plasma for Reliable Detection of Amyloid and tau PathologyJournal Name: Clinical ChemistryPublisher: Oxford University Press (OUP)Vol: 69Issue #: 11Start Page: 1247End Page: 1259Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/clinchem/hvad139Best OA location URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC10895336/pdf/nihms-1962140.pdfCitation Count: 16
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OPENTitle: Assessing the relationship between monoallelic PRKN mutations and Parkinson’s riskJournal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 30Issue #: 1Start Page: 78End Page: 86Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1093/hmg/ddaa273Best OA location URL: https://doi.org/10.1093/hmg/ddaa273Citation Count: 54
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OPENTitle: Improved measurement of disease progression in people living with early Parkinson’s disease using digital health technologiesJournal Name: Communications MedicinePublisher: Springer Science and Business Media LLCVol: 4Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s43856-024-00481-3Best OA location URL: https://www.nature.com/articles/s43856-024-00481-3.pdfCitation Count: 9
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OPENTitle: Multiomics analysis identifies novel facilitators of human dopaminergic neuron differentiationJournal Name: EMBO ReportsPublisher: Springer Science and Business Media LLCVol: 25Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s44319-023-00024-2Best OA location URL: https://doi.org/10.1038/s44319-023-00024-2Citation Count: 3
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OPENTitle: CURTAIN—A unique web-based tool for exploration and sharing of MS-based proteomics dataJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 121Issue #: 7Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-by, cc-by, cc-byDOI - Digital Object Identifier: 10.1073/pnas.2312676121Best OA location URL: https://doi.org/10.1073/pnas.2312676121Citation Count: 14
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OPENTitle: Modulation of α-synuclein in vitro aggregation kinetics by its alternative splice isoformsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 121Issue #: 7Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-by, cc-byDOI - Digital Object Identifier: 10.1073/pnas.2313465121Best OA location URL: https://doi.org/10.1073/pnas.2313465121Citation Count: 10
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OPENTitle: Parkinsonism Sac domain mutation in Synaptojanin-1 affects ciliary properties in iPSC-derived dopaminergic neuronsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 121Issue #: 17Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1073/pnas.2318943121Best OA location URL: https://doi.org/10.1073/pnas.2318943121Citation Count: 5
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OPENTitle: Bootstrap-adjusted quasi-likelihood information criteria for mixed model selectionJournal Name: Journal of Applied StatisticsPublisher: Informa UK LimitedVol: 51Issue #: 4Start Page: 621End Page: 645Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1080/02664763.2022.2143484Best OA location URL: https://figshare.com/articles/journal_contribution/Bootstrap-adjusted_quasi-likelihood_information_criteria_for_mixed_model_selection/21513884Citation Count: 4
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OPENTitle: Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseasesJournal Name: Nature GeneticsPublisher: Springer Science and Business Media LLCVol: 55Issue #: 3Start Page: 377End Page: 388Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41588-023-01300-6Best OA location URL: https://www.nature.com/articles/s41588-023-01300-6.pdfCitation Count: 172
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OPENTitle: Single-cell multiplex chromatin and RNA interactions in ageing human brainJournal Name: NaturePublisher: Springer Science and Business Media LLCVol: 628Issue #: 8008Start Page: 648End Page: 656Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41586-024-07239-wBest OA location URL: https://escholarship.org/uc/item/8449h1j7Citation Count: 32
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OPENTitle: APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microgliaJournal Name: NaturePublisher: Springer Science and Business Media LLCVol: 628Issue #: 8006Start Page: 154End Page: 161Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41586-024-07185-7Best OA location URL: https://escholarship.org/uc/item/551458jjCitation Count: 227
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OPENTitle: Prasinezumab slows motor progression in rapidly progressing early-stage Parkinson’s diseaseJournal Name: Nature MedicinePublisher: Springer Science and Business Media LLCVol: 30Issue #: 4Start Page: 1096End Page: 1103Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41591-024-02886-yBest OA location URL: https://doi.org/10.1038/s41591-024-02886-yCitation Count: 65
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OPENTitle: RAB32 Ser71Arg in autosomal dominant Parkinson's disease: linkage, association, and functional analysesJournal Name: The Lancet NeurologyPublisher: Elsevier BVVol: 23Issue #: 6Start Page: 603End Page: 614Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-by, cc-by, cc-byDOI - Digital Object Identifier: 10.1016/s1474-4422(24)00121-2Best OA location URL: http://www.thelancet.com/article/S1474442224001212/pdfCitation Count: 64
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OPENTitle: Distinctive clinical and imaging trajectories in SWEDD and Parkinson’s disease patientsJournal Name: NeuroImage: ClinicalPublisher: Elsevier BVVol: 42Issue #:Start Page: 103592End Page: 103592Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1016/j.nicl.2024.103592Best OA location URL: https://doi.org/10.1016/j.nicl.2024.103592Citation Count: 2
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OPENTitle: Federated learning for multi-omics: A performance evaluation in Parkinson’s diseaseJournal Name: PatternsPublisher: Elsevier BVVol: 5Issue #: 3Start Page: 100945End Page: 100945Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1016/j.patter.2024.100945Best OA location URL: https://doi.org/10.1016/j.patter.2024.100945Citation Count: 10
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OPENTitle: Clinical prediction of GBA carrier status in Parkinson’s diseaseJournal Name: Clinical Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 10Issue #:Start Page: 100251End Page: 100251Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1016/j.prdoa.2024.100251Best OA location URL: https://doi.org/10.1016/j.prdoa.2024.100251Citation Count: 1
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OPENTitle: Baseline genetic associations in the Parkinson's Progression Markers Initiative (PPMI)Journal Name: Movement DisordersPublisher: WileyVol: 31Issue #: 1Start Page: 79End Page: 85Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26374Best OA location URL: http://doi.org/10.1002/mds.26374Citation Count: 71
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OPENTitle: The NINDS Parkinson's disease biomarkers programJournal Name: Movement DisordersPublisher: WileyVol: 31Issue #: 6Start Page: 915End Page: 923Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26438Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4824671Citation Count: 99
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OPENTitle: Reply to letter: Plasma fasting cholesterol profiles and age at onset in Parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 30Issue #: 14Start Page: 1975End Page: 1976Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26447Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4715726Citation Count: 0
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OPENTitle: Selection of Normative Group Affects Rates of Mild Cognitive Impairment in Parkinson's DiseaseJournal Name: Movement DisordersPublisher: WileyVol: 33Issue #: 5Start Page: 839End Page: 843Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.27335Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5992013Citation Count: 18
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OPENTitle: A paradoxical relationship between family history, onset age, and genetic risk in Parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 34Issue #: 2Start Page: 298End Page: 299Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.27555Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6379106Citation Count: 3
- Correlates of excessive daytime sleepiness in de novo Parkinson's disease: A case control study2015OPENTitle: Correlates of excessive daytime sleepiness in de novo Parkinson's disease: A case control studyJournal Name: Movement DisordersPublisher: WileyVol: 30Issue #: 10Start Page: 1371End Page: 1381Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26248Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4822999Citation Count: 96
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OPENTitle: Connectivity Predicts deep brain stimulation outcome in Parkinson diseaseJournal Name: Annals of NeurologyPublisher: WileyVol: 82Issue #: 1Start Page: 67End Page: 78Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.24974Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5880678Citation Count: 609