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5851 - 5900 of 6230 Results
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  • Summary Details
    OPEN
    Title: An alpha‐synuclein MRM assay with diagnostic potential for Parkinson's disease and monitoring disease progression
    Journal Name: PROTEOMICS – Clinical Applications
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/prca.201700045
    Citation Count: 19
  • Summary Details
    OPEN
    Title: shRNA-Based Screen Identifies Endocytic Recycling Pathway Components That Act as Genetic Modifiers of Alpha-Synuclein Aggregation, Secretion and Toxicity
    Journal Name: PLOS Genetics
    Publisher: Public Library of Science (PLoS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pgen.1005995
    Citation Count: 80
  • Summary Details
    OPEN
    Title: Regulation of LRRK2 activity by metabolic stress and heavy metal exposure
    Journal Name: Brain Research
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1016/j.brainres.2025.149785
    Citation Count: 0
  • Summary Details
    OPEN
    Title: Activation of the DNA damage response in vivo in synucleinopathy models of Parkinson’s disease
    Journal Name: Cell Death & Disease
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41419-018-0848-7
    Citation Count: 107
  • Summary Details
    OPEN
    Title: The In Situ Structure of Parkinson’s Disease-Linked LRRK2
    Journal Name: Cell
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: other-oa
    DOI - Digital Object Identifier: 10.1016/j.cell.2020.08.004
    Citation Count: 192
  • Summary Details
    OPEN
    Title: Apoptosis signal regulating kinase 1 deletion mitigates α-synuclein pre-formed fibril propagation in mice
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2019.09.012
    Citation Count: 15
  • Summary Details
    OPEN
    Title: Urinary Dysfunction Is Associated with Nigrostriatal Dopaminergic Degeneration in Early and Untreated Patients with Parkinson’s Disease
    Journal Name: Parkinson's Disease
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1155/2020/4981647
    Citation Count: 12
  • Summary Details
    OPEN
    Title: A robotic and virtual testing platform highlighting the promise of soft wearable actuators for wrist tremor suppression
    Journal Name: Device
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1016/j.device.2025.100719
    Best OA location URL:
    Citation Count: 0
  • Summary Details
    OPEN
    Title: Detecting alpha-synuclein aggregates with small molecules on single-molecule array
    Journal Name: Chemical Science
    Publisher: Royal Society of Chemistry (RSC)
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1039/d4sc07649d
    Citation Count: 0
  • Summary Details
    OPEN
    Title: Human upper extremity motor cortex activity shows distinct oscillatory signatures for stereotyped arm and leg movements
    Journal Name: Frontiers in Human Neuroscience
    Publisher: Frontiers Media SA
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnhum.2023.1212963
    Citation Count: 3
  • Summary Details
    OPEN
    Title: Effects of Serine 129 Phosphorylation on α-Synuclein Aggregation, Membrane Association, and Internalization
    Journal Name: Journal of Biological Chemistry
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1074/jbc.m115.705095
    Citation Count: 145
  • Summary Details
    OPEN
    Title: Hippocampal aggregation signatures of pathogenic UBQLN2 in amyotrophic lateral sclerosis and frontotemporal dementia
    Journal Name: Brain
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc, cc-by-nc
    DOI - Digital Object Identifier: 10.1093/brain/awae140
    Citation Count: 5
  • Summary Details
    OPEN
    Title: The metabotropic glutamate receptor 8 agonist (S)-3,4-DCPG reverses motor deficits in prolonged but not acute models of Parkinson's disease
    Journal Name: Neuropharmacology
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neuropharm.2012.03.029
    Citation Count: 30
  • Summary Details
    OPEN
    Title: Metabolomics of sebum reveals lipid dysregulation in Parkinson’s disease
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41467-021-21669-4
    Citation Count: 166
  • Summary Details
    OPEN
    Title: Coordinated reset vibrotactile stimulation shows prolonged improvement in Parkinson's disease
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1002/mds.27223
    Citation Count: 35
  • Summary Details
    OPEN
    Title: NMDA receptor blockade ameliorates abnormalities of spike firing of subthalamic nucleus neurons in a parkinsonian nonhuman primate
    Journal Name: Journal of Neuroscience Research
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/jnr.24230
    Citation Count: 25
  • Summary Details
    OPEN
    Title: M1 Muscarinic Receptors Modulate Fear-Related Inputs to the Prefrontal Cortex: Implications for Novel Treatments of Posttraumatic Stress Disorder
    Journal Name: Biological Psychiatry
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: other-oa
    DOI - Digital Object Identifier: 10.1016/j.biopsych.2019.02.020
    Citation Count: 33
  • Summary Details
    OPEN
    Title: BRF110, an Orally Active Nurr1-RXRα-Selective Rexinoid, Enhances BDNF Expression without Elevating Triglycerides
    Journal Name: Journal of Medicinal Chemistry
    Publisher: American Chemical Society (ACS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1021/acs.jmedchem.4c03046
    Citation Count: 4
  • Summary Details
    OPEN
    Title: Development and Antiparkinsonian Activity of VU0418506, a Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor 4 Homomers without Activity at mGlu2/4 Heteromers
    Journal Name: ACS Chemical Neuroscience
    Publisher: American Chemical Society (ACS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/acschemneuro.6b00036
    Citation Count: 57
  • Summary Details
    OPEN
    Title: A lncRNA survey finds increases in neuroprotective LINC‐PINT in Parkinson’s disease substantia nigra
    Journal Name: Aging Cell
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1111/acel.13115
    Citation Count: 60
  • Summary Details
    OPEN
    Title: Post‐Mortem Studies of Neurturin Gene Therapy for Parkinson's Disease: Two Subjects with 10 Years CERE120 Delivery
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/mds.29518
    Citation Count: 13
  • Summary Details
    OPEN
    Title: Association between Subjective Cognitive Complaints and Incident Functional Impairment in Parkinson's Disease
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1002/mds.29725
    Citation Count: 7
  • Summary Details
    OPEN
    Title: RETRACTED: ESCRT-mediated Uptake and Degradation of Brain-targeted α-synuclein Single Chain Antibody Attenuates Neuronal Degeneration In Vivo
    Journal Name: Molecular Therapy
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-sa
    DOI - Digital Object Identifier: 10.1038/mt.2014.129
    Citation Count: 82
  • Summary Details
    OPEN
    Title: Genome-wide epigenetic analyses in Japanese immigrant plantation workers with Parkinson’s disease and exposure to organochlorines reveal possible involvement of glial genes and pathways involved in neurotoxicity
    Journal Name: BMC Neuroscience
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s12868-020-00582-4
    Citation Count: 28
  • Summary Details
    OPEN
    Title: Genetic variants related to urate and risk of Parkinson's disease
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: other-oa
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2018.04.031
    Citation Count: 6
  • Summary Details
    OPEN
    Title: Team Science Approaches to Unravel Monogenic Parkinson's Disease on a Global Scale
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1002/mds.29925
    Citation Count: 3
  • Summary Details
    OPEN
    Title: Increased burden of rare risk variants across gene expression networks predisposes to sporadic Parkinson’s disease
    Journal Name: Cell Reports
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.celrep.2025.115636
    Citation Count: 0
  • Summary Details
    OPEN
    Title: Aromaticity at position 39 in α‐synuclein: A modulator of amyloid fibril assembly and membrane‐bound conformations
    Journal Name: Protein Science
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1002/pro.4360
    Citation Count: 9
  • Summary Details
    OPEN
    Title: T lymphocyte senescence is attenuated in Parkinson’s disease
    Journal Name: Journal of Neuroinflammation
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1186/s12974-021-02287-9
    Citation Count: 31
  • Summary Details
    OPEN
    Title: 14-3-3 Proteins regulate mutant LRRK2 kinase activity and neurite shortening
    Journal Name: Human Molecular Genetics
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/hmg/ddv453
    Citation Count: 78
  • Summary Details
    OPEN
    Title: Toward the quantification of α-synuclein aggregates with digital seed amplification assays
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1073/pnas.2312031121
    Citation Count: 14
  • Summary Details
    OPEN
    Title: Pitx3 is required for development of substantia nigra dopaminergic neurons
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0230529100
    Citation Count: 382
  • Summary Details
    OPEN
    Title: Regulation of Physiologic Actions of LRRK2: Focus on Autophagy
    Journal Name: Neurodegenerative Diseases
    Publisher: S. Karger AG
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1159/000332599
    Citation Count: 39
  • Summary Details
    OPEN
    Title: Pharmacological Characterization of Membrane-Expressed Human Trace Amine-Associated Receptor 1 (TAAR1) by a Bioluminescence Resonance Energy Transfer cAMP Biosensor
    Journal Name: Molecular Pharmacology
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1124/mol.108.048884
    Citation Count: 147
  • Summary Details
    OPEN
    Title: Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson’s disease models
    Journal Name: Disease Models & Mechanisms
    Publisher: The Company of Biologists
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1242/dmm.004267
    Citation Count: 178
  • Summary Details
    OPEN
    Title: The Parkinson’s disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability
    Journal Name: Cell
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd, cc-by-nc-nd, cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.cell.2022.05.008
    Citation Count: 115
  • Summary Details
    OPEN
    Title: Open science takes on Parkinson’s disease
    Journal Name: eLife
    Publisher: eLife Sciences Publications, Ltd
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.7554/elife.66546
    Citation Count: 7
  • Summary Details
    OPEN
    Title: Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021
    Journal Name: The Lancet
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by, cc-by, cc-by
    DOI - Digital Object Identifier: 10.1016/s0140-6736(24)00685-8
    Citation Count: 394
  • Summary Details
    OPEN
    Title: SAMTOR is anS-adenosylmethionine sensor for the mTORC1 pathway
    Journal Name: Science
    Publisher: American Association for the Advancement of Science (AAAS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/science.aao3265
    Citation Count: 463
  • Summary Details
    OPEN
    Title: Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau
    Journal Name: Journal of Clinical Investigation
    Publisher: American Society for Clinical Investigation
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1172/jci78421
    Best OA location URL:
    Citation Count: 194
  • Summary Details
    OPEN
    Title: Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions
    Journal Name: Neuron
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by, cc-by
    DOI - Digital Object Identifier: 10.1016/j.neuron.2024.06.002
    Citation Count: 11
  • Summary Details
    OPEN
    Title: JNK2 and JNK3 combined are essential for apoptosis in dopamine neurons of the substantia nigra, but are not required for axon degeneration
    Journal Name: Journal of Neurochemistry
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/j.1471-4159.2008.05713.x
    Citation Count: 79
  • Summary Details
    OPEN
    Title: Hsp104 antagonizes α-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease
    Journal Name: Journal of Clinical Investigation
    Publisher: American Society for Clinical Investigation
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1172/jci35781
    Citation Count: 195
  • Summary Details
    OPEN
    Title: EndoMAP.v1 charts the structural landscape of human early endosome complexes
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1038/s41586-025-09059-y
    Citation Count: 0
  • Summary Details
    OPEN
    Title: Evaluation of the PREDIGT score’s performance in identifying newly diagnosed Parkinson’s patients without motor examination
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-022-00360-5
    Citation Count: 4
  • Summary Details
    OPEN
    Title: Role for NUP62 depletion and PYK2 redistribution in dendritic retraction resulting from chronic stress
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1418896111
    Citation Count: 50
  • Summary Details
    OPEN
    Title: Functional network differences between unilateral and bilateral deep brain stimulation of the subthalamic nucleus
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1038/s41531-025-01064-2
    Citation Count: 0
  • Summary Details
    OPEN
    Title: Mapping movement, mood, motivation and mentation in the subthalamic nucleus
    Journal Name: Royal Society Open Science
    Publisher: The Royal Society
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1098/rsos.171177
    Citation Count: 34
  • Summary Details
    OPEN
    Title: Bifunctional Anti-Non-Amyloid Component α-Synuclein Nanobodies Are Protective In Situ
    Journal Name: PLOS ONE
    Publisher: Public Library of Science (PLoS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pone.0165964
    Citation Count: 63
  • Summary Details
    OPEN
    Title: The experience of off periods: Qualitative analysis of interviews with persons with Parkinson's and carepartners
    Journal Name: Clinical Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.prdoa.2019.07.008
    Citation Count: 10
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