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MJFF Publications

3851 - 3900 of 5832 Results
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  • OPEN
    Title: Inhibition of LRRK2 or Casein Kinase 1 Results in LRRK2 Protein Destabilization
    Journal Name: Molecular Neurobiology
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1007/s12035-018-1449-2
    Citation Count: 15
  • OPEN
    Title: Neurite Collapse and Altered ER Ca2+ Control in Human Parkinson Disease Patient iPSC-Derived Neurons with LRRK2 G2019S Mutation
    Journal Name: Stem Cell Reports
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.stemcr.2018.11.021
    Citation Count: 66
  • OPEN
    Title: Ultra–Low-Dose18F-Florbetaben Amyloid PET Imaging Using Deep Learning with Multi-Contrast MRI Inputs
    Journal Name: Radiology
    Publisher: Radiological Society of North America (RSNA)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1148/radiol.2018180940
    Citation Count: 202
  • OPEN
    Title: Effects of Novel Calpain Inhibitors in Transgenic Animal Model of Parkinson’s disease/dementia with Lewy bodies
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-018-35729-1
    Citation Count: 24
  • OPEN
    Title: Tau immunoreactivity in peripheral tissues of human aging and select tauopathies
    Journal Name: Neuroscience Letters
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neulet.2018.12.031
    Citation Count: 43
  • OPEN
    Title: Large-scale validation of miRNAs by disease association, evolutionary conservation and pathway activity
    Journal Name: RNA Biology
    Publisher: Informa UK Limited
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1080/15476286.2018.1559689
    Citation Count: 7
  • OPEN
    Title: Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease
    Journal Name: Acta Neuropathologica
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1007/s00401-018-1947-3
    Citation Count: 109
  • OPEN
    Title: Effects of APOE Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease
    Journal Name: Frontiers in Molecular Neuroscience
    Publisher: Frontiers Media SA
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnmol.2018.00454
    Citation Count: 62
  • OPEN
    Title: A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41593-018-0298-7
    Citation Count: 184
  • OPEN
    Title: Entorhinal Cortex Atrophy in Early, Drug-naive Parkinson’s Disease with Mild Cognitive Impairment
    Journal Name: Aging and disease
    Publisher: Aging and Disease
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.14336/ad.2018.1116
    Citation Count: 39
  • OPEN
    Title: Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer’s disease
    Journal Name: Acta Neuropathologica
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1007/s00401-018-1948-2
    Citation Count: 137
  • OPEN
    Title: Comparative sensitivity of the MoCA and Mattis Dementia Rating Scale‐2 in Parkinson's disease
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27575
    Citation Count: 17
  • OPEN
    Title: Regional gray matter changes and age predict individual treatment response in Parkinson's disease
    Journal Name: NeuroImage: Clinical
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.nicl.2018.101636
    Citation Count: 25
  • OPEN
    Title: Non-motor predictors of freezing of gait in Parkinson’s disease
    Journal Name: Gait & Posture
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.gaitpost.2018.12.009
    Citation Count: 44
  • OPEN
    Title: Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson's disease and DLB
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1073/pnas.1813365115
    Citation Count: 73
  • OPEN
    Title: Characterizing patient compliance over six months in remote digital trials of Parkinson’s and Huntington disease
    Journal Name: BMC Medical Informatics and Decision Making
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s12911-018-0714-7
    Citation Count: 32
  • OPEN
    Title: Destabilizing Domains Enable Long-Term and Inert Regulation of GDNF Expression in the Brain
    Journal Name: Molecular Therapy - Methods & Clinical Development
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.omtm.2018.08.008
    Citation Count: 16
  • OPEN
    Title: The atypical RhoGTPase RhoE/Rnd3 is a key molecule to acquire a neuroprotective phenotype in microglia
    Journal Name: Journal of Neuroinflammation
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s12974-018-1386-z
    Citation Count: 14
  • OPEN
    Title: CoREST Complex-Selective Histone Deacetylase Inhibitors Show Prosynaptic Effects and an Improved Safety Profile To Enable Treatment of Synaptopathies
    Journal Name: ACS Chemical Neuroscience
    Publisher: American Chemical Society (ACS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License: publisher-specific-oa
    DOI - Digital Object Identifier: 10.1021/acschemneuro.8b00620
    Citation Count: 39
  • OPEN
    Title: Parkinson-Associated SNCA Enhancer Variants Revealed by Open Chromatin in Mouse Dopamine Neurons
    Journal Name: The American Journal of Human Genetics
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: publisher-specific-oa
    DOI - Digital Object Identifier: 10.1016/j.ajhg.2018.10.018
    Citation Count: 34
  • OPEN
    Title: A paradoxical relationship between family history, onset age, and genetic risk in Parkinson's disease
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27555
    Citation Count: 3
  • OPEN
    Title: Computational affinity maturation of camelid single-domain intrabodies against the nonamyloid component of alpha-synuclein
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-018-35464-7
    Citation Count: 39
  • OPEN
    Title: Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia
    Journal Name: Nature Medicine
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41591-018-0223-3
    Citation Count: 121
  • OPEN
    Title: Understanding the role of genetic variability in LRRK2 in Indian population
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27558
    Citation Count: 13
  • OPEN
    Title: Intracellular metalloprotease activity controls intraneuronal Aβ aggregation and limits secretion of Aβviaexosomes
    Journal Name: The FASEB Journal
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1096/fj.201801319r
    Citation Count: 35
  • OPEN
    Title: Information processing deficit in older adults with HIV infection: A comparison with Parkinson’s disease.
    Journal Name: Neuropsychology
    Publisher: American Psychological Association (APA)
    Publication Date:
    Open Access(OA) Status: OPEN
    License: publisher-specific, author manuscript
    DOI - Digital Object Identifier: 10.1037/neu0000500
    Citation Count: 3
  • OPEN
    Title: Wearable sensors for Parkinson’s disease: which data are worth collecting for training symptom detection models
    Journal Name: npj Digital Medicine
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41746-018-0071-z
    Citation Count: 170
  • OPEN
    Title: Genetic analysis of neurodegenerative diseases in a pathology cohort
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2018.11.007
    Citation Count: 29
  • OPEN
    Title: Joint modeling of multivariate longitudinal data and survival data in several observational studies of Huntington’s disease
    Journal Name: BMC Medical Research Methodology
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s12874-018-0592-9
    Citation Count: 49
  • OPEN
    Title: Benefits of pallidal stimulation in dystonia are linked to cerebellar volume and cortical inhibition
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-018-34880-z
    Citation Count: 13
  • OPEN
    Title: Recruitment of patients with de novo Parkinson disease: successful strategies in a randomized exercise clinical trial
    Journal Name: Trials
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s13063-018-2958-z
    Citation Count: 11
  • OPEN
    Title: RAB7L1-Mediated Relocalization of LRRK2 to the Golgi Complex Causes Centrosomal Deficits via RAB8A
    Journal Name: Frontiers in Molecular Neuroscience
    Publisher: Frontiers Media SA
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnmol.2018.00417
    Citation Count: 42
  • OPEN
    Title: Evidence for increased completed suicide in first-degree relatives of LRRK2 G2019S mutation Parkinson’s disease
    Journal Name: Journal of Neurology, Neurosurgery & Psychiatry
    Publisher: BMJ
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1136/jnnp-2018-319364
    Citation Count: 0
  • OPEN
    Title: Magnetic resonance T1w/T2w ratio: A parsimonious marker for Parkinson disease
    Journal Name: Annals of Neurology
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/ana.25376
    Citation Count: 36
  • OPEN
    Title: Calpain-mediated tau fragmentation is altered in Alzheimer’s disease progression
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-018-35130-y
    Citation Count: 43
  • OPEN
    Title: A pathway for Parkinson’s Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain
    Journal Name: eLife
    Publisher: eLife Sciences Publications, Ltd
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.7554/elife.40202
    Citation Count: 219
  • OPEN
    Title: Synthesis and in Vivo Evaluation of a Novel PET Radiotracer for Imaging of Synaptic Vesicle Glycoprotein 2A (SV2A) in Nonhuman Primates
    Journal Name: ACS Chemical Neuroscience
    Publisher: American Chemical Society (ACS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/acschemneuro.8b00526
    Citation Count: 92
  • OPEN
    Title: Portrait of blood-derived extracellular vesicles in patients with Parkinson’s disease
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2018.11.002
    Citation Count: 42
  • OPEN
    Title: RAB7A phosphorylation by TBK1 promotes mitophagy via the PINK-PARKIN pathway
    Journal Name: Science Advances
    Publisher: American Association for the Advancement of Science (AAAS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc, cc-by-nc
    DOI - Digital Object Identifier: 10.1126/sciadv.aav0443
    Citation Count: 162
  • OPEN
    Title: Serum Insulin-Like Growth Factor-1 in Parkinson's Disease; Study of Cerebrospinal Fluid Biomarkers and White Matter Microstructure
    Journal Name: Frontiers in Endocrinology
    Publisher: Frontiers Media SA
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fendo.2018.00608
    Citation Count: 16
  • OPEN
    Title: Dissociation between urate and blood pressure in mice and in people with early Parkinson's disease
    Journal Name: EBioMedicine
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.ebiom.2018.10.039
    Citation Count: 9
  • OPEN
    Title: Phosphorylation of Parkin at serine 65 is essential for its activationin vivo
    Journal Name: Open Biology
    Publisher: The Royal Society
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1098/rsob.180108
    Citation Count: 102
  • OPEN
    Title: Predicting early cognitive decline in newly-diagnosed Parkinson's patients: A practical model
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2018.06.031
    Citation Count: 23
  • OPEN
    Title: The E3 Ubiquitin Ligases TRIM17 and TRIM41 Modulate α-Synuclein Expression by Regulating ZSCAN21
    Journal Name: Cell Reports
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.celrep.2018.11.002
    Citation Count: 32
  • OPEN
    Title: Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.aah4066
    Citation Count: 623
  • OPEN
    Title: Metabolomic Profiling of Bile Acids in an Experimental Model of Prodromal Parkinson’s Disease
    Journal Name: Metabolites
    Publisher: MDPI AG
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3390/metabo8040071
    Citation Count: 49
  • OPEN
    Title: The Parkinson's progression markers initiative (PPMI) – establishing a PD biomarker cohort
    Journal Name: Annals of Clinical and Translational Neurology
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/acn3.644
    Citation Count: 440
  • OPEN
    Title: The vermiform appendix impacts the risk of developing Parkinson’s disease
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.aar5280
    Citation Count: 232
  • OPEN
    Title: δ-Secretase-cleaved Tau stimulates Aβ production via upregulating STAT1-BACE1 signaling in Alzheimer’s disease
    Journal Name: Molecular Psychiatry
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41380-018-0286-z
    Citation Count: 66
  • OPEN
    Title: A Proposed Roadmap for Parkinson’s Disease Proof of Concept Clinical Trials Investigating Compounds Targeting Alpha-Synuclein
    Journal Name: Journal of Parkinson's Disease
    Publisher: SAGE Publications
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.3233/jpd-181471
    Citation Count: 49
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