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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2022
    Assessing the Aggregation of Alpha-synuclein in the Gastrointestinal Tract

    Study Rationale: A growing body of evidence suggests that Parkinson’s disease (PD) may begin in the stomach or elsewhere along the gastrointestinal (GI) tract before spreading to the brain. If this...

  • Research Grant, 2022
    Cognitive Assessment of Non-Human Primate Models of Parkinson's Disease

    Study Rationale: Cognitive impairments cause significant disability for people with Parkinson’s disease (PD). Problems such as reduced attention or difficulty following plans can occur very early in...

  • Biomarkers to Support Therapeutic Trials Program, 2023
    Using the Chemical Modification of Alpha-synuclein to Define Disease State and Facilitate Patient Stratification in Parkinson’s Disease

    Study Rationale: Novel disease-modifying treatments for Parkinson’s disease (PD) are urgently needed as the prevalence of the disease is increasing and no cure is available. At this point, we have...

  • Research Resources, 2022
    Neural Network Imaging Analysis in Parkinson’s Disease Associated with Parkin Mutation

    Study Rationale: Clinical imaging biomarkers are desperately needed to provide a non-invasive means of assessing therapeutic efficacy in clinical trials for Parkinson’s disease (PD). Recent studies...

  • Summer 2022 RFP: The Edmond J. Safra Movement Disorders Research Career Development Award, 2022
    Assessing Sensorimotor Integration in Monogenic Parkinson-dystonia Syndromes

    Study Rationale: Inherited Parkinson-dystonia syndromes are rare but ideal models for studying genetically complex disorders, such as Parkinson’s disease (PD), as their underlying cause — mutation in...

  • Target Advancement Program, 2022
    Mining for Protein Aberrations in Parkinson’s Disease Using Large-Scale Protein Databases

    Study Rationale: Deficient clearance of misfolded alpha-synuclein aggregates contributes to the pathology of Parkinson’s disease (PD). But broader disturbances in proteostasis—the balanced production...

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