The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2014Reduced Habitual Intrusions: An Early Marker of Parkinson's Disease?
Study Rationale:
Parkinson's disease is characterized by the loss of a neurotransmitter called dopamine in a part of the brain called the basal ganglia. Parts of this region are... -
Improved Neuromodulation Approaches, 2014Responsive, Closed-Loop Approach to Treat Freezing of Gait in Parkinson’s Disease
Study Rationale:
Levodopa-resistant posture, gait and freezing symptoms are among the most disabling and difficult to treat in people with Parkinson’s disease (PD). Recent findings... -
Target Validation, 2014Seeking Neuroprotection via a Novel Complex-1 Chaperone
Objective/Rationale:
Mitochondria are the powerplants of the cell, and decades of evidence suggest that they may be defective in the brains of people with Parkinson’s. The overall goal of... -
Therapeutic Pipeline Program, 2014Evaluation of the Oligomer Modulator anle138b in a Seeding-based Model of Parkinson’s Disease
Objective/Rationale:
Mounting evidence indicates a crucial role of pathological aggregates of the protein alpha-synuclein in Parkinson’s disease (PD). Small aggregates termed oligomers... -
Target Validation, 2014Targeting the Stress Sensor PERK for the Treatment of Parkinson´s Disease
Objective/Rationale:
Parkinson's disease (PD) is characterized by impairment of motor control as a result from extensive neuron death. The primary mechanism responsible for the progressive... -
Improved Neuromodulation Approaches, 2014Optogenetic Restoration of Basal Ganglia Function to Treat Parkinson’s Disease
Study Rationale:
Optogenetics has gained wide interest as a tool to understand the function of circuits influencing brain diseases. This approach uses proteins that respond to...
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Our funding programs support basic, translational and clinical research from academia and industry.