Funded Studies

Study Rationale: Polyamines are molecules that show neuroprotective effects, and one of the genes that is mutated in Parkinson’s disease (PD), ATP13A2, regulates cellular polyamine levels. Unpublished...

Study Rationale: A growing body of research suggests that low doses of carbon monoxide (CO) protect against neuronal cell loss in Parkinson’s disease (PD). Preclinical efficacy data in two rodent...

Study Rationale: Genetic mutations resulting in a depletion of glucosylceramidase activity is the most predisposing risk factor for developing Parkinson’s disease (PD). Activating glucosylceramidase...

Study Rationale: REM sleep behavior disorder is well recognized as a prodromal condition associated with a high risk of subsequently developing neurodegenerative disorders termed synucleinopathies...

Study Rationale: There is currently no disease-modifying treatment for Parkinson’s disease (PD) or Lewy body dementia (LBD). One possible reason is that both of these disorders are highly...

Study Rationale: In Parkinson’s disease (PD), a protein called alpha-synuclein builds up inside of brain cells. Research suggests that this protein accumulation damages the cells and eventually leads...