The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2020Parkinson’s Disease with Mild Cognitive Impairment Treated with a Nicotinic Agonist Drug
Study Rationale:
Parkinson’s disease with mild cognitive impairment (PD-MCI) is common, has important clinical consequences, and there is currently no treatment available. The underlying pathology of... -
Research Grant, 2020Detecting Colonic Alpha-synuclein with an Antibody Specific for Disease-associated Forms as a Biomarker of Parkinson’s Disease
Study Rationale:
Despite several published studies using different anti-alpha-synuclein antibodies, to date no lab-based methods have been able to reliably identify Parkinson’s disease (PD) cases from... -
Research Grant Supplement, 2020LIMP-2 as a Scaffolding Protein to Characterize PD-Associated GCase Variants
Promising Outcomes of Original Grant:
Our original grant focused on determining the structure of the complex formed by the Parkinson’s-associated protein beta-gluccocerebrosidase (GCase) and its... -
Research Grant, 2020Targeted and Untargeted Mass Spectrometry-Based Proteome Investigation of Urine in Parkinson’s Disease
Study Rationale:
There is an urgent need for disease indicators — also known as biomarkers — in Parkinson’s disease to enable early diagnoses and treatment response monitoring. Urine is a promising... -
Research Grant, 2020Assessing Target Engagement for Terazosin
Study Rationale:
Patients with Parkinson’s disease (PD) do not produce enough of a compound called ATP. If a person does not make enough ATP, the cells in the body can die. This is very important... -
Research Grant, 2020Safety and Tolerability of NLX-112 in People with Parkinson’s
Study Rationale:
Motor symptoms of Parkinson’s disease are caused by a lack of brain neurons that carry a neurotransmitter called dopamine, and are commonly treated with levodopa. However, after...
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Our funding programs support basic, translational and clinical research from academia and industry.