3671 - 3680 of 8826 Results
Title
Year
- Quinazolin-4-one Derivatives: A Novel Class of Noncompetitive NR2C/D Subunit-SelectiveN-Methyl-d-aspartate Receptor Antagonists2010OPENTitle: Quinazolin-4-one Derivatives: A Novel Class of Noncompetitive NR2C/D Subunit-SelectiveN-Methyl-d-aspartate Receptor AntagonistsJournal Name: Journal of Medicinal ChemistryPublisher: American Chemical Society (ACS)Vol: 53Issue #: 15Start Page: 5476End Page: 5490Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/jm100027pCitation Count: 84
- Discovery, Synthesis, and Structure–Activity Relationship Development of a Series of N-4-(2,5-Dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): Characterization of a Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 (mGlu4) with Oral Efficacy in an Antiparkinsonian Animal Model2011OPENTitle: Discovery, Synthesis, and Structure–Activity Relationship Development of a Series of N-4-(2,5-Dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): Characterization of a Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 (mGlu4) with Oral Efficacy in an Antiparkinsonian Animal ModelJournal Name: Journal of Medicinal ChemistryPublisher: American Chemical Society (ACS)Vol: 54Issue #: 21Start Page: 7639End Page: 7647Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/jm200956qCitation Count: 59
-
OPENTitle: Characterization of TAE684 as a potent LRRK2 kinase inhibitorJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 22Issue #: 5Start Page: 1864End Page: 1869Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2012.01.084Best OA location URL: http://hdl.handle.net/10871/35667Citation Count: 85
-
OPENTitle: Administration and Scoring Variance on the ADAS-CogJournal Name: Journal of Alzheimer's DiseasePublisher: SAGE PublicationsVol: 15Issue #: 3Start Page: 461End Page: 464Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3233/jad-2008-15312Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2727511Citation Count: 83
-
OPENTitle: Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neuronsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 104Issue #: 4Start Page: 1325End Page: 1330Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0605208103Best OA location URL: http://doi.org/10.1073/pnas.0605208103Citation Count: 578
-
OPENTitle: Balancing the basal ganglia circuitry: A possible new role for dopamine D2 receptors in health and diseaseJournal Name: Movement DisordersPublisher: WileyVol: 30Issue #: 7Start Page: 895End Page: 903Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26282Best OA location URL: http://doi.org/10.1002/mds.26282Citation Count: 47
- Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS)2010OPENTitle: Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS)Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 20Issue #: 17Start Page: 5175End Page: 5178Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2010.07.007Citation Count: 29
-
OPENTitle: Allopregnanolone Reinstates Tyrosine Hydroxylase Immunoreactive Neurons and Motor Performance in an MPTP-Lesioned Mouse Model of Parkinson's DiseaseJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 7Issue #: 11Start Page: e50040End Page: e50040Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0050040Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0050040&type=printableCitation Count: 50
-
OPENTitle: Vitamin D Status During Pregnancy and Risk of Multiple Sclerosis in Offspring of Women in the Finnish Maternity CohortJournal Name: JAMA NeurologyPublisher: American Medical Association (AMA)Vol: 73Issue #: 5Start Page: 515End Page: 515Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/jamaneurol.2015.4800Best OA location URL: https://jamanetwork.com/journals/jamaneurology/articlepdf/2499458/noi150103.pdfCitation Count: 169
-
OPENTitle: Solution-Phase Parallel Synthesis and SAR of Homopiperazinyl Analogs as Positive Allosteric Modulators of mGlu4Journal Name: ACS Combinatorial SciencePublisher: American Chemical Society (ACS)Vol: 13Issue #: 2Start Page: 159End Page: 165Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/co1000508Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3057427Citation Count: 8