5341 - 5350 of 9131 Results
Title
Year
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OPENTitle: Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivoJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 110Issue #: 41Start Page: E3945End Page: 54Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1309991110Best OA location URL: https://infoscience.epfl.ch/handle/20.500.14299/94836Citation Count: 213
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OPENTitle: Abrogation of α-synuclein–mediated dopaminergic neurodegeneration in LRRK2-deficient ratsJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 111Issue #: 25Start Page: 9289End Page: 9294Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1403215111Best OA location URL: https://www.pnas.org/content/pnas/111/25/9289.full.pdfCitation Count: 224
- α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation2015OPENTitle: α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylationJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 112Issue #: 15Start Page: E1926End Page: 35Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1417883112Best OA location URL: https://www.pnas.org/content/pnas/112/15/E1926.full.pdfCitation Count: 150
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RESTRICTEDTitle: Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged miceJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 107Issue #: 21Start Page: 9879End Page: 9884Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1073/pnas.1004676107Best OA location URL: http://doi.org/10.1073/pnas.1004676107Citation Count: 510
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OPENTitle: Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3Journal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 111Issue #: 1Start Page: E34End Page: 43Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1312701111Best OA location URL: https://www.pnas.org/content/pnas/111/1/E34.full.pdfCitation Count: 127
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OPENTitle: Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutationsJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 109Issue #: 26Start Page: 10322End Page: 10327Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1203223109Best OA location URL: https://www.pnas.org/content/pnas/109/26/10322.full.pdfCitation Count: 99
- Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP12014OPENTitle: Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1Journal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 111Issue #: 18Start Page: 6804End Page: 6809Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1321845111Best OA location URL: https://infoscience.epfl.ch/handle/20.500.14299/104291Citation Count: 215
- Chromosomal amplification of leucine-rich repeat kinase-2 (LRRK2) is required for oncogenic MET signaling in papillary renal and thyroid carcinomas2011RESTRICTEDTitle: Chromosomal amplification of leucine-rich repeat kinase-2 (LRRK2) is required for oncogenic MET signaling in papillary renal and thyroid carcinomasJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 108Issue #: 4Start Page: 1439End Page: 1444Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1073/pnas.1012500108Citation Count: 95
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OPENTitle: Highly pathogenic H5N1 influenza virus can enter the central nervous system and induce neuroinflammation and neurodegenerationJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 106Issue #: 33Start Page: 14063End Page: 14068Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0900096106Best OA location URL: http://doi.org/10.1073/pnas.0900096106Citation Count: 461
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OPENTitle: In vivo demonstration that α-synuclein oligomers are toxicJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 108Issue #: 10Start Page: 4194End Page: 4199Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1100976108Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3053976Citation Count: 1494