6931 - 6940 of 8587 Results
Title
Year
- Allosteric modulation of the GTPase activity of a bacterial LRRK2 homolog by conformation-specific Nanobodies2020OPENTitle: Allosteric modulation of the GTPase activity of a bacterial LRRK2 homolog by conformation-specific NanobodiesJournal Name: Biochemical JournalPublisher: Portland Press Ltd.Vol: 477Issue #: 7Start Page: 1203End Page: 1218Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1042/bcj20190843Citation Count: 17
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OPENTitle: Pathogenic LRRK2 requires secondary factors to induce cellular toxicityJournal Name: Bioscience ReportsPublisher: Portland Press Ltd.Vol: 40Issue #: 10Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1042/bsr20202225Best OA location URL: https://portlandpress.com/bioscirep/article-pdf/40/10/BSR20202225/894975/bsr-2020-2225.pdfCitation Count: 1
- Translation of the intrinsically disordered protein α-synuclein is inhibited by a small molecule targeting its structured mRNA2020OPENTitle: Translation of the intrinsically disordered protein α-synuclein is inhibited by a small molecule targeting its structured mRNAJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 117Issue #: 3Start Page: 1457End Page: 1467Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1073/pnas.1905057117Best OA location URL: https://www.pnas.org/content/pnas/117/3/1457.full.pdfCitation Count: 95
- Tensor decomposition of stimulated monocyte and macrophage gene expression profiles identifies neurodegenerative disease-specific trans-eQTLs2020OPENTitle: Tensor decomposition of stimulated monocyte and macrophage gene expression profiles identifies neurodegenerative disease-specific trans-eQTLsJournal Name: PLOS GeneticsPublisher: Public Library of Science (PLoS)Vol: 16Issue #: 2Start Page: e1008549End Page: e1008549Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pgen.1008549Best OA location URL: https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1008549&type=printableCitation Count: 27
- Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity2020OPENTitle: Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activityJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 117Issue #: 29Start Page: 17296End Page: 17307Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1073/pnas.1922184117Best OA location URL: https://www.pnas.org/content/pnas/117/29/17296.full.pdfCitation Count: 57
- Transcriptomic stratification of late-onset Alzheimer's cases reveals novel genetic modifiers of disease pathology2020OPENTitle: Transcriptomic stratification of late-onset Alzheimer's cases reveals novel genetic modifiers of disease pathologyJournal Name: PLOS GeneticsPublisher: Public Library of Science (PLoS)Vol: 16Issue #: 6Start Page: e1008775End Page: e1008775Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pgen.1008775Best OA location URL: https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1008775&type=printableCitation Count: 45
- Improvement of classification performance of Parkinson’s disease using shape features for machine learning on dopamine transporter single photon emission computed tomography2020OPENTitle: Improvement of classification performance of Parkinson’s disease using shape features for machine learning on dopamine transporter single photon emission computed tomographyJournal Name: PLOS ONEPublisher: Public Library of Science (PLoS)Vol: 15Issue #: 1Start Page: e0228289End Page: e0228289Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0228289Best OA location URL: https://doi.org/10.1371/journal.pone.0228289Citation Count: 34
- The turning and barrier course reveals gait parameters for detecting freezing of gait and measuring the efficacy of deep brain stimulation2020OPENTitle: The turning and barrier course reveals gait parameters for detecting freezing of gait and measuring the efficacy of deep brain stimulationJournal Name: PLOS ONEPublisher: Public Library of Science (PLoS)Vol: 15Issue #: 4Start Page: e0231984End Page: e0231984Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0231984Best OA location URL: https://doi.org/10.1371/journal.pone.0231984Citation Count: 35
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OPENTitle: Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucoseJournal Name: PLOS ONEPublisher: Public Library of Science (PLoS)Vol: 15Issue #: 5Start Page: e0230815End Page: e0230815Publication Date:Open Access(OA) Status: OPENLicense: cc0, cc0DOI - Digital Object Identifier: 10.1371/journal.pone.0230815Best OA location URL: https://escholarship.org/content/qt01585271/qt01585271.pdfCitation Count: 33
- Interpretation of health-related quality of life outcomes in Parkinson’s disease from the EARLYSTIM Study2020OPENTitle: Interpretation of health-related quality of life outcomes in Parkinson’s disease from the EARLYSTIM StudyJournal Name: PLOS ONEPublisher: Public Library of Science (PLoS)Vol: 15Issue #: 8Start Page: e0237498End Page: e0237498Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0237498Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0237498&type=printableCitation Count: 13