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7131 - 7140 of 8761 Results
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  • A novel systems biology approach to evaluate mouse models of late-onset Alzheimer’s disease
    2020
    Summary Details
    OPEN
    Title: A novel systems biology approach to evaluate mouse models of late-onset Alzheimer’s disease
    Author(s): Christoph Preuß, Ravi S. Pandey, Erin Piazza, Alexander D. Fine, Aslı Uyar, Thanneer M. Perumal, Dylan Garceau, Kevin P. Kotredes, Harriet M. Williams, Lara M. Mangravite, Bruce T. Lamb, Adrian L. Oblak, Gareth R. Howell, Michael Sasner, Benjamin A. Logsdon, Gregory W. Carter
    Journal Name: Molecular Neurodegeneration
    Publisher: Springer Science and Business Media LLC
    Vol: 15
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s13024-020-00412-5
    Best OA location URL: https://molecularneurodegeneration.biomedcentral.com/track/pdf/10.1186/s13024-020-00412-5
    Citation Count: 52
  • Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction
    2020
    Summary Details
    OPEN
    Title: Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction
    Author(s): Colin K. Deniston, John Salogiannis, Sebastian Mathea, David Snead, Indrajit Lahiri, Mariusz Matyszewski, Oscar Donosa, Reika Watanabe, Jan Böhning, Andrew K. Shiau, Stefan Knapp, Elizabeth Villa, Samara L. Reck‐Peterson, Andres E. Leschziner
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 588
    Issue #: 7837
    Start Page: 344
    End Page: 349
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41586-020-2673-2
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7726071
    Citation Count: 203
  • Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophy
    2020
    Summary Details
    OPEN
    Title: Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophy
    Author(s): Mohammad Shahnawaz, Abhisek Mukherjee, Sandra Pritzkow, Nicolás Méndez, Prakruti Rabadia, Xiangan Liu, Bo Hu, Ann M. Schmeichel, Wolfgang Singer, Gang Wu, Ah-Lim Tsai, Hamid Shirani, K. Peter R. Nilsson, Phillip A. Low, Claudio Soto
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 578
    Issue #: 7794
    Start Page: 273
    End Page: 277
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41586-020-1984-7
    Citation Count: 661
  • All that’s fit to preprint
    2020
    Summary Details
    OPEN
    Title: All that’s fit to preprint
    Author(s):
    Journal Name: Nature Biotechnology
    Publisher: Springer Science and Business Media LLC
    Vol: 38
    Issue #: 5
    Start Page: 507
    End Page: 507
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41587-020-0536-x
    Best OA location URL: https://www.nature.com/articles/s41587-020-0536-x.pdf
    Citation Count: 11
  • Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity
    2020
    Summary Details
    OPEN
    Title: Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity
    Author(s): Amberley D. Stephens, Maria Zacharopoulou, Rani Moons, Giuliana Fusco, Neeleema Seetaloo, Anass Chiki, Philippa J. Woodhams, Ioanna Mela, Hilal A. Lashuel, Jonathan J. Phillips, Alfonso De Simone, Frank Sobott, Gabriele S. Kaminski Schierle
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 11
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1038/s41467-020-16564-3
    Best OA location URL: https://www.nature.com/articles/s41467-020-16564-3.pdf
    Citation Count: 140
  • Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration
    2020
    Summary Details
    OPEN
    Title: Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration
    Author(s): Insup Choi, Yuanxi Zhang, Steven P. Seegobin, Mathilde Pruvost, Qian Wang, Kerry Purtell, Bin Zhang, Zhenyu Yue
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 11
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41467-020-15119-w
    Best OA location URL: https://www.nature.com/articles/s41467-020-15119-w.pdf
    Citation Count: 409
  • When antibodies mislead: the quest for validation
    2020
    Summary Details
    RESTRICTED
    Title: When antibodies mislead: the quest for validation
    Author(s): Monya Baker
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 585
    Issue #: 7824
    Start Page: 313
    End Page: 314
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/d41586-020-02549-1
    Citation Count: 37
  • Molecular estimation of neurodegeneration pseudotime in older brains
    2020
    Summary Details
    OPEN
    Title: Molecular estimation of neurodegeneration pseudotime in older brains
    Author(s): Sumit Mukherjee, Laura Heath, Christoph Preuß, Suman Jayadev, Gwenn A. Garden, Anna K. Greenwood, Solveig K. Sieberts, Philip L. De Jager, Nilüfer Ertekin‐Taner, Gregory W. Carter, Lara M. Mangravite, Benjamin A. Logsdon
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 11
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41467-020-19622-y
    Best OA location URL: https://www.nature.com/articles/s41467-020-19622-y.pdf
    Citation Count: 50
  • Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study
    2020
    Summary Details
    OPEN
    Title: Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study
    Author(s): Eric M. Reiman, Joseph F. Arboleda‐Velásquez, Yakeel T. Quiroz, Matthew J. Huentelman, Thomas G. Beach, Richard J. Caselli, Yinghua Chen, Yi Su, Amanda Myers, John Hardy, Jean Paul Vonsattel, Steven G. Younkin, David Bennett, Philip L. De Jager, Eric B. Larson, Paul K. Crane, C. Dirk Keene, M. Ilyas Kamboh, Julia Kofler, Linda Duque, John R. Gilbert, Harry E. Gwirtsman, Joseph D. Buxbaum, Dennis W. Dickson, Matthew P. Frosch, Bernardino Ghetti, Kathryn L. Lunetta, Li-San Wang, Bradley T. Hyman, Walter A. Kukull, Tatiana M. Foroud, Jonathan L. Haines, Richard Mayeux, Margaret A. Pericak‐Vance, Julie A. Schneider, John Q. Trojanowski, Lindsay A. Farrer, Gerard D. Schellenberg, Gary W. Beecham, Thomas J. Montine, Gyungah Jun, Erin L. Abner, Perrie M. Adams, Marilyn S. Albert, Roger L. Albin, Liana G. Apostolova, Steven E. Arnold, Sanjay Asthana, Craig Atwood, Clinton T. Baldwin, Robert C. Barber, Lisa L. Barnes, Sandra Barral, James T. Becker, Duane Beekly, Eileen H. Bigio, Thomas D. Bird, Deborah Blacker, Bradley F. Boeve, James D. Bowen, Adam Boxer, James R. Burke, Jeffrey M. Burns, Nigel J. Cairns, Laura B. Cantwell, Chuanhai Cao, Chris Carlson, Cynthia M. Carlsson, Regina M. Carney, Minerva M. Carrasquillo, Helena C. Chui, David H. Cribbs, Elizabeth Crocco, Carlos Cruchaga, Charles DeCarli, Malcolm Dick, Rachelle S. Doody, Ranjan Duara, Nilüfer Ertekin‐Taner, Denis A. Evans, Kelley Faber, Thomas Fairchild, Kenneth B. Fallon, David W. Fardo, Martin R. Farlow, Steven H. Ferris, Douglas Galasko, Marla Gearing, Daniel H. Geschwind, Valentina Ghisays, Alison Goate, Neill R. Graff‐Radford, Robert C. Green, John H. Growdon, Hákon Hákonarson, Ronald L. Hamilton, Kara L. Hamilton‐Nelson, Lindy E. Harrell, Lawrence S. Honig, Ryan M. Huebinger, Christine M. Hulette, Gail P. Jarvik, Lee‐Way Jin, Anna Karydas, Mindy J. Katz, John Kauwe, Jonathan Kaye, Ronald Kim, Neil W. Kowall, Joel H. Kramer, Brian W. Kunkle, Amanda P. Kuzma, Frank M. LaFerla, James J. Lah, Yuk Yee Leung, James B. Leverenz, Allan I. Levey, Ge Li, Andrew P. Lieberman, Richard Lipton, Oscar L. López, Constantine G. Lyketsos, John Malamon, Daniel Marson, Eden R. Martin, Frank Martiniuk, Deborah C. Mash, Eliezer Masliah, Wayne C. McCormick, Susan M. McCurry, Andrew McDavid, Stefan McDonough, Ann C. McKee, Marsel Mesulam, Bruce L. Miller, Carol A. Miller, Joshua W. Miller, John C. Morris, Shubhabrata Mukherjee, Adam C. Naj, Sid E. O’Bryant, John Olichney, Joseph E. Parisi, Henry L. Paulson, Elaine R. Peskind, Ronald Petersen, Aimee Pierce, Wayne W. Poon, Huntington Potter, Liming Qu, Joseph F. Quinn, Ashok Raj, Murray A. Raskind, ‌Barry Reisberg, Joan Reisch, Christiane Reitz, John M. Ringman, Erik D. Roberson, Ekaterina Rogaeva, Howard J. Rosen, Roger N. Rosenberg, Donald R. Royall, Mark A. Sager, Mary Sano, Andrew J. Saykin, Lon S. Schneider, William W. Seeley, Amanda Smith, Joshua A. Sonnen, Salvatore Spina, Peter St George‐Hyslop, Robert A. Stern, Russell H. Swerdlow, Rudolph E. Tanzi, Juan C. Troncoso, Debby W. Tsuang, Otto Valladares, Vivianna M. Van Deerlin, Linda J. Van Eldik, Badri N. Vardarajan, Harry V. Vinters, Sandra Weıntraub, Kathleen A. Welsh‐Bohmer, Kirk C. Wilhelmsen, Jennifer Williamson, Thomas S. Wingo, Randall L. Woltjer, Clinton B. Wright, Chuang-Kuo Wu, Chang‐En Yu, Lei Yu, Yi Zhao
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 11
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41467-019-14279-8
    Best OA location URL: https://escholarship.org/uc/item/2n48k3rk
    Citation Count: 397
  • Diagnostic value of plasma phosphorylated tau181 in Alzheimer’s disease and frontotemporal lobar degeneration
    2020
    Summary Details
    OPEN
    Title: Diagnostic value of plasma phosphorylated tau181 in Alzheimer’s disease and frontotemporal lobar degeneration
    Author(s): Elisabeth H. Thijssen, Renaud La Joie, Amy Wolf, Amelia Strom, Ping Wang, Leonardo Iaccarino, Viktoriya Bourakova, Yann Cobigo, Hilary W. Heuer, Salvatore Spina, Lawren VandeVrede, Xiyun Chai, Nicholas K. Proctor, David Airey, Sergey Shcherbinin, Cynthia Evans, John R. Sims, Henrik Zetterberg, Kaj Blennow, Anna M. Karydas, Charlotte E. Teunissen, Joel H. Kramer, Lea T. Grinberg, William W. Seeley, Howie Rosen, Bradley F. Boeve, Bruce L. Miller, Gil D. Rabinovici, Jeffrey L. Dage, Julio C. Rojas, Adam L. Boxer
    Journal Name: Nature Medicine
    Publisher: Springer Science and Business Media LLC
    Vol: 26
    Issue #: 3
    Start Page: 387
    End Page: 397
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41591-020-0762-2
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7101073
    Citation Count: 657
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